Fatty acid-binding protein, heart

NameFatty acid-binding protein, heart
Synonyms
  • FABP11
  • Fatty acid-binding protein 3
  • H-FABP
  • Heart-type fatty acid-binding protein
  • M-FABP
  • Mammary-derived growth inhibitor
  • MDGI
  • Muscle fatty acid-binding protein
Gene NameFABP3
OrganismHuman
Amino acid sequence
>lcl|BSEQ0010836|Fatty acid-binding protein, heart
MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKN
TEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTH
GTAVCTRTYEKEA
Number of residues133
Molecular Weight14857.93
Theoretical pI6.8
GO Classification
Functions
  • cytoskeletal protein binding
  • icosatetraenoic acid binding
  • long-chain fatty acid binding
  • long-chain fatty acid transporter activity
  • oleic acid binding
Processes
  • positive regulation of phospholipid biosynthetic process
  • regulation of fatty acid oxidation
  • small molecule metabolic process
  • triglyceride catabolic process
  • negative regulation of cell proliferation
  • cholesterol homeostasis
  • phospholipid homeostasis
  • response to insulin
  • response to fatty acid
  • fatty acid metabolic process
  • long-chain fatty acid import
  • response to drug
Components
  • cytosol
  • extracellular exosome
  • sarcoplasm
  • extracellular space
General FunctionOleic acid binding
Specific FunctionFABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein ID31293
UniProtKB IDP05413
UniProtKB Entry NameFABPH_HUMAN
Cellular LocationCytoplasm
Gene sequence
>lcl|BSEQ0010837|Fatty acid-binding protein, heart (FABP3)
ATGGTGGACGCTTTCCTGGGCACCTGGAAGCTAGTGGACAGCAAGAATTTCGATGACTAC
ATGAAGTCACTCGGTGTGGGTTTTGCTACCAGGCAGGTGGCCAGCATGACCAAGCCTACC
ACAATCATCGAAAAGAATGGGGACATTCTCACCCTAAAAACACACAGCACCTTCAAGAAC
ACAGAGATCAGCTTTAAGTTGGGGGTGGAGTTCGATGAGACAACAGCAGATGACAGGAAG
GTCAAGTCCATTGTGACACTGGATGGAGGGAAACTTGTTCACCTGCAGAAATGGGACGGG
CAAGAGACCACACTTGTGCGGGAGCTAATTGATGGAAAACTCATCCTGACACTCACCCAC
GGCACTGCAGTTTGCACTCGCACTTATGAGAAAGAGGCATGA
GenBank Gene IDX56549
GeneCard IDNot Available
GenAtlas IDFABP3
HGNC IDHGNC:3557
Chromosome Location1
Locus1p33-p32
References
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