NameMalate dehydrogenase, mitochondrial
Synonyms
  • 1.1.1.37
Gene NameMDH2
OrganismHuman
Amino acid sequence
>lcl|BSEQ0037074|Malate dehydrogenase, mitochondrial
MLSALARPASAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH
TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATI
VATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTF
VAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKA
KAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIE
KNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK
Number of residues338
Molecular Weight35502.935
Theoretical pI8.9
GO Classification
Functions
  • poly(A) RNA binding
  • L-malate dehydrogenase activity
  • malate dehydrogenase (NADP+) activity
Processes
  • gluconeogenesis
  • small molecule metabolic process
  • carbohydrate metabolic process
  • glucose metabolic process
  • cellular metabolic process
  • oxaloacetate metabolic process
  • tricarboxylic acid cycle
  • malate metabolic process
  • NADH metabolic process
  • internal protein amino acid acetylation
Components
  • plasma membrane
  • extracellular exosome
  • myelin sheath
  • nucleoplasm
  • mitochondrion
  • nucleus
  • mitochondrial inner membrane
  • mitochondrial matrix
General FunctionPoly(a) rna binding
Specific FunctionNot Available
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein ID2906146
UniProtKB IDP40926
UniProtKB Entry NameMDHM_HUMAN
Cellular LocationMitochondrion matrix
Gene sequence
>lcl|BSEQ0010551|Malate dehydrogenase, mitochondrial (MDH2)
ATGCTCTCCGCCCTCGCCCGGCCTGCCAGCGCTGCTCTCCGCCGCAGCTTCAGCACCTCG
GCCCAGAACAATGCTAAAGTAGCTGTGCTAGGGGCCTCTGGAGGCATCGGGCAGCCACTT
TCACTTCTCCTGAAGAACAGCCCCTTGGTGAGCCGCCTGACCCTCTATGATATCGCGCAC
ACACCCGGAGTGGCCGCAGATCTGAGCCACATCGAGACCAAAGCCGCTGTGAAAGGCTAC
CTCGGACCTGAACAGCTGCCTGACTGCCTGAAAGGTTGTGATGTGGTAGTTATTCCGGCT
GGAGTCCCCAGAAAGCCAGGCATGACCCGGGACGACCTGTTCAACACCAATGCCACGATT
GTGGCCACCCTGACCGCTGCCTGTGCCCAGCACTGCCCGGAAGCCATGATCTGCGTCATT
GCCAATCCGGGTTTGGATCCAGCTCGAGTCAACGTCCCTGTCATTGGTGGCCATGCTGGG
AAGACCATCATCCCCCTGATCTCTCAGTGCACCCCCAAGGTGGACTTTCCCCAGGACCAG
CTGACAGCACTCACTGGGCGGATCCAGGAGGCCGGCACGGAGGTGGTCAAGGCTAAAGCC
GGAGCAGGCTCTGCCACCCTCTCCATGGCGTATGCCGGCGCCCGCTTTGTCTTCTCCCTT
GTGGATGCAATGAATGGAAAGGAAGGTGTTGTGGAATGTTCCTTCGTTAAGTCACAGGAA
ACGGAATGTACCTACTTCTCCACACCGCTGCTGCTTGGGAAAAAGGGCATCGAGAAGAAC
CTGGGCATCGGCAAAGTCTCCTCTTTTGAGGAGAAGATGATCTCGGATGCCATCCCCGAG
CTGAAGGCCTCCATCAAGAAGGGGGAAGATTTCGTGAAGACCCTGAAGTGA
GenBank Gene IDAF047470
GeneCard IDNot Available
GenAtlas IDMDH2
HGNC IDHGNC:6971
Chromosome Location7
Locus7p12.3-q11.2
References
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