NameProtein phosphatase 1 regulatory subunit 7
Synonyms
  • Protein phosphatase 1 regulatory subunit 22
  • SDS22
Gene NamePPP1R7
OrganismHuman
Amino acid sequence
>lcl|BSEQ0009134|Protein phosphatase 1 regulatory subunit 7
MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKHSSGIVADLSEQSLKDGEERGEEDPE
EEHELPVDMETINLDRDAEDVDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLEELQ
SLRELDLYDNQIKKIENLEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIE
NLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN
RLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQE
FWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALPSVRQIDATFVRF
Number of residues360
Molecular Weight41563.805
Theoretical pINot Available
GO Classification
Functions
  • enzyme regulator activity
  • protein phosphatase type 1 regulator activity
Processes
  • positive regulation of protein dephosphorylation
  • chromosome segregation
  • regulation of catalytic activity
Components
  • cytoplasm
  • nucleus
  • chromosome
  • extracellular exosome
General FunctionProtein phosphatase type 1 regulator activity
Specific FunctionRegulatory subunit of protein phosphatase 1.
Pfam Domain FunctionNot Available
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDQ15435
UniProtKB Entry NamePP1R7_HUMAN
Cellular LocationNucleus
Gene sequence
>lcl|BSEQ0017698|Protein phosphatase 1 regulatory subunit 7 (PPP1R7)
ATGGCGGCGGAACGCGGCGCGGGGCAGCAACAGTCGCAGGAGATGATGGAGGAAGAACAT
GAGCTGCCTGTGGACATGGAAACCATCAACCTGGACAGAGATGCAGAGGATGTTGATTTG
AATCACTATCGCATAGGGAAGATTGAAGGATTTGAGGTACTGAAGAAAGTGAAGACTCTC
TGCCTCCGCCAAAATTTAATTAAATGCATTGAGAATCTGGAGGAGCTACAGAGTCTTCGA
GAGCTGGATCTTTACGACAACCAGATCAAGAAGATTGAGAATCTGGAGGCGCTAACAGAG
CTGGAGATTCTAGATATTTCTTTTAATCTGCTGAGAAACATCGAAGGGGTTGACAAGTTG
ACACGACTGAAAAAACTCTTCTTGGTCAACAATAAAATCAGTAAAATTGAGAACTTAAGC
AACTTACATCAACTACAGATGCTAGAGCTGGGATCTAACCGCATCCGGGCAATCGAAAAT
ATCGACACCTTAACCAACCTGGAGAGTTTGTTTTTGGGGAAAAACAAAATTACTAAACTT
CAGAACCTGGATGCGCTCACCAACCTGACAGTCCTCAGTATGCAGAGCAACCGGCTGACC
AAGATCGAGGGTCTGCAGAACCTGGTGAACCTGCGGGAGCTGTACCTTAGCCACAATGGC
ATCGAGGTCATCGAGGGCCTGGAGAACAATAACAAACTCACGATGTTGGACATTGCATCA
AATAGAATCAAAAAGATTGAAAATATCAGCCATCTAACAGAGCTGCAAGAGTTCTGGATG
AACGACAATCTCCTTGAGAGCTGGAGCGACCTCGACGAGCTGAAGGGAGCCAGGAGCCTG
GAGACAGTGTACCTGGAGCGGAACCCCTTGCAGAAGGACCCCCAGTACCGGCGGAAGGTC
ATGCTCGCCCTCCCCTCCGTGCGGCAGATCGATGCCACGTTCGTCAGGTTCTGA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:9295
Chromosome Location2
LocusNot Available
References
  1. Renouf S, Beullens M, Wera S, Van Eynde A, Sikela J, Stalmans W, Bollen M: Molecular cloning of a human polypeptide related to yeast sds22, a regulator of protein phosphatase-1. FEBS Lett. 1995 Nov 13;375(1-2):75-8. 7498485
  2. Ceulemans H, Van Eynde A, Perez-Callejon E, Beullens M, Stalmans W, Bollen M: Structure and splice products of the human gene encoding sds22, a putative mitotic regulator of protein phosphatase-1. Eur J Biochem. 1999 May;262(1):36-42. 10231361
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