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NameHistone H2A type 3
SynonymsNot Available
Gene NameHIST3H2A
OrganismHuman
Amino acid sequence
>lcl|BSEQ0013498|Histone H2A type 3
MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLT
AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKK
TESHHKAKGK
Number of residues130
Molecular Weight14121.355
Theoretical pINot Available
GO Classification
Functions
  • DNA binding
Processes
  • chromatin silencing
  • UV-damage excision repair
  • nucleosome disassembly
Components
  • extracellular exosome
  • nuclear nucleosome
General FunctionDna binding
Specific FunctionCore component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDQ7L7L0
UniProtKB Entry NameH2A3_HUMAN
Cellular LocationNucleus
Gene sequence
>lcl|BSEQ0013499|Histone H2A type 3 (HIST3H2A)
ATGTCCGGTCGTGGTAAGCAGGGTGGCAAGGCGCGCGCCAAGGCTAAGTCGCGCTCGTCG
CGCGCGGGGCTGCAGTTCCCCGTGGGCCGCGTGCACCGGTTGCTCCGCAAGGGCAACTAT
TCGGAGCGCGTGGGCGCCGGCGCCCCGGTCTATCTGGCCGCGGTGCTCGAGTACTTGACT
GCCGAGATCCTGGAGCTTGCCGGCAACGCGGCGCGCGACAACAAGAAGACGCGCATCATC
CCGCGCCACCTGCAGCTGGCCATCCGCAACGACGAGGAGCTCAACAAGCTGCTGGGCCGC
GTGACCATCGCGCAGGGTGGCGTCCTGCCCAACATCCAGGCCGTACTGCTGCCCAAGAAG
ACGGAGAGCCACCACAAGGCCAAGGGCAAGTGA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:20507
Chromosome Location1
LocusNot Available
References
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