Histone H1oo
| Name | Histone H1oo |
|---|---|
| Synonyms |
|
| Gene Name | H1FOO |
| Organism | Human |
| Amino acid sequence | >lcl|BSEQ0008902|Histone H1oo MAPGSVTSDISPSSTSTAGSSRSPESEKPGPSHGGVPPGGPSHSSLPVGRRHPPVLRMVL EALQAGEQRRGTSVAAIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLARPLNSKARG ATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRP AKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKA KGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAA APAKGSGSKVVPAHLSRKTEAPKGPRKAGLPIKASSSKVSSQRAEA |
| Number of residues | 346 |
| Molecular Weight | 35813.185 |
| Theoretical pI | Not Available |
| GO Classification | Functions
Processes
Components
|
| General Function | Nucleosomal dna binding |
| Specific Function | May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling (By similarity). |
| Pfam Domain Function |
|
| Transmembrane Regions | Not Available |
| GenBank Protein ID | Not Available |
| UniProtKB ID | Q8IZA3 |
| UniProtKB Entry Name | H1FOO_HUMAN |
| Cellular Location | Cytoplasm |
| Gene sequence | >lcl|BSEQ0013487|Histone H1oo (H1FOO) ATGGCCCCCGCGACGGCTCCCAGGAGAGCGGGTGAGGCCAAGGGGAAGGGCCCCAAGAAA CCAAGTGAGGCCAAGGAGGACCCTCCCAACGTGGGCAAGGTGAAAAAGGCAGCCAAGAGG CCAGCAAAGGTGCAGAAGCCTCCTCCCAAGCCAGGCGCAGCCACAGAGAAGGCTCGCAAG CAAGGCGGCGCGGCCAAGGACACCAGGGCACAGTCGGGAGAGGCTAGGAAGGTGCCCCCC AAGCCAGACAAGGCCATGCGGGCACCTTCCAGTGCTGGTGGGCTCAGCAGGAAGGCAAAG GCCAAAGGCAGCAGGAGCAGCCAAGGAGATGCTGAGGCCTACAGGAAAACCAAAGCTGAG AGTAAGAGTTCAAAACCCACGGCCAGCAAGGTCAAGAATGGTGCTGCTTCCCCGACCAAA AAGAAGGTGGTGGCCAAGGCCAAGGCCCCTAAAGCTGGGCAGGGGCCAAACACCAAGGCT GCTGCTCCTGCTAAGGGCAGTGGGTCCAAGGTGGTACCTGCACATTTGTCCAGGAAGACA GAGGCCCCCAAGGGCCCTAGAAAGGCTGGGCTGCCCATCAAGGCCTCATCATCCAAAGTG TCCAGCCAGAGGGCTGAAGCTTAG |
| GenBank Gene ID | Not Available |
| GeneCard ID | Not Available |
| GenAtlas ID | Not Available |
| HGNC ID | HGNC:18463 |
| Chromosome Location | 3 |
| Locus | Not Available |
| References |
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