T3DB: ATPase family AAA domain-containing protein 5

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Name	ATPase family AAA domain-containing protein 5
Synonyms	C17orf41 Chromosome fragility-associated gene 1 protein FRAG1
Gene Name	ATAD5
Organism	Human
Amino acid sequence	>lcl\|BSEQ0009301\|ATPase family AAA domain-containing protein 5 MVGVLAMAAAAAPPPVKDCEIEPCKKRKKDDDTSTCKTITKYLSPLGKTRDRVFAPPKPS NILDYFRKTSPTNEKTQLGKECKIKSPESVPVDSNKDCTTPLEMFSNVEFKKKRKRVNLS HQLNNIKTENEAPIEISSDDSKEDYSLNNDFVESSTSVLRYKKQVEVLAENIQDTKSQPN TMTSLQNSKKVNPKQGTTKNDFKKLRKRKCRDVVDLSESLPLAEELNLLKKDGKDTKQME NTTSHANSRDNVTEAAQLNDSIITVSYEEFLKSHKENKVEEIPDSTMSICVPSETVDEIV KSGYISESENSEISQQVRFKTVTVLAQVHPIPPKKTGKIPRIFLKQKQFEMENSLSDPEN EQTVQKRKSNVVIQEEELELAVLEAGSSEAVKPKCTLEERQQFMKAFRQPASDALKNGVK KSSDKQKDLNEKCLYEVGRDDNSKKIMENSGIQMVSKNGNLQLHTDKGSFLKEKNKKLKK KNKKTLDTGAIPGKNREGNTQKKETTFFLKEKQYQNRMSLRQRKTEFFKSSTLFNNESLV YEDIANDDLLKVSSLCNNNKLSRKTSIPVKDIKLTQSKAESEASLLNVSTPKSTRRSGRI SSTPTTETIRGIDSDDVQDNSQLKASTQKAANLSEKHSLYTAELITVPFDSESPIRMKFT RISTPKKSKKKSNKRSEKSEATDGGFTSQIRKASNTSKNISKAKQLIEKAKALHISRSKV TEEIAIPLRRSSRHQTLPERKKLSETEDSVIIIDSSPTALKHPEKNQKKLQCLNDVLGKK LNTSTKNVPGKMKVAPLFLVRKAQKAADPVPSFDESSQDTSEKSQDCDVQCKAKRDFLMS GLPDLLKRQIAKKAAALDVYNAVSTSFQRVVHVQQKDDGCCLWHLKPPSCPLLTKFKELN TKVIDLSKCGIALGEFSTLNSKLKSGNSAAVFMRTRKEFTEEVRNLLLEEIRWSNPEFSL KKYFPLLLKKQIEHQVLSSECHSKQELEADVSHKETKRKLVEAENSKSKRKKPNEYSKNL EKTNRKSEELSKRNNSSGIKLDSSKDSGTEDMLWTEKYQPQTASELIGNELAIKKLHSWL KDWKRRAELEERQNLKGKRDEKHEDFSGGIDFKGSSDDEEESRLCNTVLITGPTGVGKTA AVYACAQELGFKIFEVNASSQRSGRQILSQLKEATQSHQVDKQGVNSQKPCFFNSYYIGK SPKKISSPKKVVTSPRKVPPPSPKSSGPKRALPPKTLANYFKVSPKPKNNEEIGMLLENN KGIKNSFEQKQITQTKSTNATNSNVKDVGAEEPSRKNATSLILFEEVDVIFDEDAGFLNA IKTFMATTKRPVILTTSDPTFSLMFDGCFEEIKFSTPSLLNVASYLQMICLTENFRTDVK DFVTLLTANTCDIRKSILYLQFWIRSGGGVLEERPLTLYRGNSRNVQLVCSEHGLDNKIY PKNTKKKRVDLPKCDSGCAETLFGLKNIFSPSEDLFSFLKHKITMKEEWHKFIQLLTEFQ MRNVDFLYSNLEFILPLPVDTIPETKNFCGPSVTVDASAATKSMNCLARKHSEREQPLKK SQKKKQKKTLVILDDSDLFDTDLDFPDQSISLSSVSSSSNAEESKTGDEESKARDKGNNP ETKKSIPCPPKTTAGKKCSALVSHCLNSLSEFMDNMSFLDALLTDVREQNKYGRNDFSWT NGKVTSGLCDEFSLESNDGWTSQSSGELKAAAEALSFTKCSSAISKALETLNSCKKLGRD PTNDLTFYVSQKRNNVYFSQSAANLDNAWKRISVIKSVFSSRSLLYVGNRQASIIEYLPT LRNICKTEKLKEQGKSKRRFLHYFEGIHLDIPKETVNTLAADFP
Number of residues	1844
Molecular Weight	207568.185
Theoretical pI	Not Available
GO Classification	Functions ATP binding Processes cellular response to DNA damage stimulus Components nucleus
General Function	Atp binding
Specific Function	Involved in DNA damage response. Involved in a RAD9A-related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages-induced apoptosis.
Pfam Domain Function	AAA (PF00004 )
Transmembrane Regions	Not Available
GenBank Protein ID	Not Available
UniProtKB ID	Q96QE3
UniProtKB Entry Name	ATAD5_HUMAN
Cellular Location	Nucleus
Gene sequence	>lcl\|BSEQ0013728\|ATPase family AAA domain-containing protein 5 (ATAD5) ATGGTGGGGGTCCTGGCCATGGCGGCTGCAGCTGCTCCGCCTCCCGTGAAGGACTGCGAG ATTGAGCCATGCAAAAAGCGAAAGAAAGATGATGACACATCTACCTGCAAAACAATTACA AAATATTTATCACCACTAGGGAAGACTAGAGACAGGGTTTTTGCTCCACCAAAACCTAGT AATATTCTGGATTATTTTAGAAAGACTTCACCCACAAATGAGAAGACACAATTAGGGAAA GAGTGCAAGATAAAGTCACCTGAATCAGTACCTGTTGACAGCAACAAAGACTGTACGACA CCTTTGGAAATGTTCTCAAATGTAGAGTTTAAGAAGAAAAGAAAGAGGGTTAATTTATCT CATCAACTAAATAATATTAAAACTGAAAATGAAGCTCCAATTGAAATTAGTAGCGACGAT AGCAAAGAAGACTATAGTTTAAATAATGATTTTGTGGAAAGTAGTACTTCTGTTTTACGT TACAAGAAACAAGTAGAGGTACTTGCAGAAAACATTCAAGATACAAAAAGTCAACCAAAT ACTATGACCTCCCTGCAAAATTCTAAAAAAGTAAATCCTAAACAAGGGACCACAAAAAAT GACTTCAAAAAGTTGAGAAAAAGGAAATGCAGAGATGTAGTAGATCTATCTGAAAGCTTA CCCTTGGCAGAGGAACTAAATTTGCTTAAAAAAGATGGTAAAGATACTAAACAGATGGAG AATACTACAAGCCATGCAAACTCTAGAGATAACGTAACTGAAGCAGCCCAGTTAAATGAT AGTATAATAACTGTCTCATATGAGGAATTTTTAAAAAGTCACAAGGAAAATAAAGTGGAA GAGATACCAGACTCTACAATGTCAATTTGTGTTCCTTCTGAAACTGTCGACGAAATAGTC AAAAGTGGTTATATAAGTGAATCAGAAAACTCCGAAATTTCCCAGCAGGTACGCTTTAAG ACAGTTACTGTTCTTGCACAGGTTCACCCTATTCCGCCCAAAAAGACAGGGAAAATACCC CGAATTTTCTTGAAACAAAAGCAATTTGAAATGGAAAATAGTTTATCTGATCCTGAGAAT GAACAGACAGTTCAGAAAAGAAAATCTAATGTTGTTATACAGGAGGAAGAATTAGAATTG GCTGTTTTGGAAGCTGGAAGTTCTGAAGCTGTGAAACCAAAATGCACTCTAGAAGAAAGA CAGCAATTTATGAAAGCATTTAGGCAGCCAGCATCAGATGCACTTAAAAATGGAGTTAAA AAGTCTTCTGATAAGCAGAAAGACCTTAATGAAAAATGTCTATATGAAGTAGGAAGAGAT GATAATTCTAAAAAAATCATGGAAAATTCTGGTATCCAAATGGTTTCAAAAAATGGCAAT TTACAGTTACACACTGATAAAGGAAGTTTTCTGAAGGAGAAAAATAAAAAGCTAAAGAAG AAGAATAAGAAAACATTAGATACTGGGGCTATTCCAGGCAAAAACAGAGAGGGAAACACT CAAAAGAAAGAAACAACCTTTTTCTTAAAAGAGAAACAATATCAAAATAGAATGAGTTTA AGACAAAGGAAAACAGAGTTTTTCAAAAGCAGCACTTTATTTAACAATGAAAGTCTTGTT TATGAAGATATAGCAAATGATGACCTTCTAAAGGTTTCCTCTCTGTGTAACAATAATAAA TTGTCAAGAAAAACCAGCATACCAGTTAAAGATATTAAGCTTACACAGTCTAAAGCTGAA TCTGAAGCCAGCTTGCTAAATGTTTCCACGCCCAAGTCAACTAGAAGATCTGGAAGAATT AGCAGCACACCTACTACAGAAACCATTAGAGGTATTGATTCTGACGATGTACAAGATAAT AGTCAACTAAAGGCTTCCACTCAAAAAGCAGCCAACTTATCGGAAAAGCACAGCTTATAT ACAGCAGAATTAATAACAGTACCCTTTGATTCAGAGAGCCCTATTAGAATGAAATTCACC AGAATTAGTACTCCCAAAAAATCTAAGAAAAAATCTAACAAAAGATCTGAGAAATCTGAA GCAACTGATGGAGGTTTTACTTCTCAGATTAGAAAGGCAAGCAATACTTCAAAAAACATA TCAAAAGCAAAACAATTGATTGAAAAAGCAAAAGCTTTACACATCAGTAGGTCAAAGGTG ACTGAAGAAATAGCGATACCCTTAAGGCGCTCCTCTAGACATCAGACACTTCCTGAAAGG AAGAAATTGTCAGAAACAGAAGATTCTGTTATAATAATAGATTCAAGTCCTACTGCTTTA AAGCATCCAGAGAAAAATCAGAAGAAACTTCAGTGTTTGAATGATGTGCTAGGAAAAAAA CTTAACACATCCACTAAAAATGTACCTGGAAAAATGAAAGTCGCTCCTTTATTTCTTGTC AGAAAAGCACAAAAAGCAGCTGATCCTGTCCCTAGTTTTGATGAAAGCAGTCAAGATACA TCTGAAAAATCTCAGGATTGTGATGTTCAATGTAAAGCAAAGCGTGACTTCCTAATGAGT GGTTTGCCAGATTTGTTGAAACGGCAAATTGCAAAGAAAGCTGCTGCGCTGGATGTGTAC AATGCAGTGAGTACCAGTTTCCAGAGAGTCGTACATGTGCAACAAAAGGATGATGGGTGT TGTTTGTGGCATTTGAAACCACCCTCTTGTCCTCTCTTAACTAAATTTAAAGAACTGAAC ACTAAAGTAATAGATCTCTCAAAATGTGGTATTGCTCTTGGTGAATTTTCAACATTGAAT TCAAAGTTGAAAAGCGGTAACTCTGCTGCTGTGTTCATGAGGACAAGGAAGGAATTTACT GAAGAAGTAAGAAATCTTTTGCTTGAGGAAATTAGGTGGTCAAATCCTGAATTTTCATTG AAAAAATATTTTCCCTTACTCCTAAAAAAACAAATTGAGCACCAAGTACTTTCTTCCGAG TGTCATAGTAAACAAGAACTGGAGGCTGATGTCAGCCATAAAGAAACCAAAAGGAAACTC GTAGAAGCAGAAAATTCTAAGTCAAAAAGAAAGAAACCAAATGAGTATTCAAAAAATCTG GAGAAGACCAATAGGAAGTCAGAAGAACTTAGCAAAAGAAACAACTCTTCTGGGATAAAG CTAGATTCTTCCAAAGATTCTGGAACTGAAGACATGCTTTGGACAGAAAAGTATCAACCT CAGACTGCCAGTGAACTTATAGGAAATGAGTTAGCTATAAAAAAGTTACATAGTTGGTTG AAAGACTGGAAAAGAAGAGCTGAATTGGAAGAAAGGCAGAATCTGAAGGGAAAAAGAGAT GAGAAACATGAAGATTTCTCGGGTGGCATAGACTTTAAAGGCAGTTCAGATGATGAAGAA GAGAGTCGTCTTTGCAATACTGTCCTTATAACAGGGCCAACAGGAGTGGGAAAAACTGCT GCAGTGTATGCTTGTGCCCAGGAGCTTGGATTTAAGATATTTGAAGTGAATGCCTCTTCC CAGCGCAGTGGTAGACAAATTCTATCTCAGTTGAAGGAAGCTACTCAGTCCCATCAAGTA GACAAACAAGGTGTAAACTCACAAAAACCCTGTTTTTTTAATAGCTACTACATAGGCAAG TCACCAAAAAAAATAAGCTCCCCTAAGAAAGTTGTTACATCACCAAGAAAAGTTCCTCCA CCATCACCAAAAAGTAGTGGACCAAAGCGAGCACTTCCTCCCAAAACCTTGGCAAATTAT TTTAAAGTATCTCCCAAACCTAAAAATAATGAAGAAATAGGAATGCTTCTGGAAAATAAT AAAGGAATAAAAAATTCTTTTGAACAGAAACAAATTACTCAGACTAAATCTACAAATGCA ACTAATTCAAATGTCAAAGACGTTGGAGCTGAAGAACCCAGCAGAAAAAATGCAACATCT CTTATTCTTTTTGAGGAGGTTGATGTAATTTTTGATGAAGATGCTGGGTTTTTGAATGCA ATCAAAACATTCATGGCAACAACTAAACGACCTGTAATCCTTACTACAAGTGACCCAACA TTTAGTTTAATGTTTGATGGCTGCTTTGAAGAAATCAAGTTCAGTACTCCTTCCCTGCTA AATGTTGCCAGCTACCTACAAATGATTTGCTTAACTGAGAATTTTAGAACTGATGTAAAA GACTTTGTAACCTTGTTAACTGCAAATACTTGTGATATCAGAAAAAGTATCCTTTACTTA CAATTCTGGATTAGAAGTGGAGGTGGAGTTTTAGAAGAACGACCATTAACCCTTTATCGT GGAAATAGCAGAAATGTACAACTAGTTTGCTCTGAACATGGCCTTGATAACAAAATTTAC CCTAAAAATACTAAAAAGAAACGTGTAGACCTTCCAAAATGTGACAGTGGCTGTGCTGAG ACCTTGTTTGGCCTTAAGAACATTTTTTCCCCATCTGAAGACTTATTTTCATTTTTAAAG CACAAAATCACAATGAAGGAAGAATGGCATAAATTCATCCAGCTTCTTACAGAATTCCAA ATGCGGAATGTAGATTTTTTATATAGTAATCTTGAGTTTATTCTACCATTACCAGTTGAT ACCATTCCAGAAACTAAAAACTTTTGTGGCCCATCAGTAACTGTGGATGCCAGTGCAGCA ACAAAAAGTATGAATTGTCTTGCTAGGAAACACTCTGAAAGAGAACAGCCATTGAAAAAG TCCCAGAAAAAGAAACAAAAGAAAACATTGGTAATATTAGATGATAGTGATCTATTTGAC ACTGACTTGGACTTTCCTGATCAATCTATTAGCCTGTCCTCTGTATCATCTTCCTCAAAT GCAGAAGAAAGCAAAACCGGAGACGAAGAAAGCAAAGCCAGAGACAAAGGAAACAATCCA GAGACAAAGAAATCTATTCCTTGTCCTCCTAAAACAACTGCAGGAAAAAAATGTTCTGCC CTTGTTTCTCATTGTTTAAATTCTCTCTCTGAGTTCATGGATAACATGTCCTTCTTAGAT GCACTTTTAACTGATGTAAGGGAACAAAACAAATACGGTAGAAATGACTTTAGTTGGACA AATGGAAAGGTTACAAGTGGACTTTGTGATGAGTTTAGTCTTGAGAGTAATGATGGATGG ACTTCTCAAAGCTCTGGAGAATTAAAGGCAGCTGCAGAAGCTCTCAGCTTTACTAAATGT TCTTCTGCTATTTCAAAAGCATTGGAAACCTTGAATTCTTGCAAGAAATTAGGAAGAGAT CCAACCAACGATCTTACTTTTTATGTTTCACAAAAGCGCAATAATGTATACTTTAGTCAG TCAGCAGCTAATTTAGACAATGCTTGGAAGAGGATATCAGTCATTAAAAGTGTATTTTCG AGTCGATCTCTTCTCTATGTGGGTAATAGACAAGCTAGTATAATTGAATACCTGCCAACC CTTCGAAACATCTGTAAGACTGAGAAGCTAAAAGAACAAGGAAAAAGTAAAAGAAGATTC CTGCACTATTTTGAAGGAATTCATCTTGACATTCCAAAAGAGACTGTGAATACTTTGGCA GCTGACTTCCCTTAA
GenBank Gene ID	Not Available
GeneCard ID	Not Available
GenAtlas ID	Not Available
HGNC ID	HGNC:25752
Chromosome Location	17
Locus	Not Available
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