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NameHistone H2B type 1-N
Synonyms
  • H2B/d
  • H2BFD
  • Histone H2B.d
Gene NameHIST1H2BN
OrganismHuman
Amino acid sequence
>lcl|BSEQ0017641|Histone H2B type 1-N
MPEPSKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAM
GIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVT
KYTSSK
Number of residues126
Molecular Weight13922.035
Theoretical pINot Available
GO Classification
Functions
  • DNA binding
Processes
  • chromatin organization
  • nucleosome assembly
Components
  • cytoplasm
  • nucleus
  • extracellular exosome
  • nucleoplasm
  • nuclear nucleosome
  • nucleosome
General FunctionDna binding
Specific FunctionCore component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDQ99877
UniProtKB Entry NameH2B1N_HUMAN
Cellular LocationNucleus
Gene sequence
>lcl|BSEQ0017642|Histone H2B type 1-N (HIST1H2BN)
ATGCCCGAGCCCTCAAAGTCCGCTCCTGCCCCGAAGAAAGGCTCCAAGAAGGCAGTGACA
AAGGCCCAGAAGAAGGACGGCAAGAAGCGCAAGCGCAGCCGCAAGGAGAGCTACTCCGTG
TACGTGTACAAGGTGCTGAAGCAGGTCCACCCCGACACCGGTATCTCGTCCAAGGCCATG
GGCATCATGAACTCCTTCGTCAATGACATCTTCGAGCGCATCGCCGGCGAGGCTTCCCGC
CTGGCGCATTACAACAAGCGCTCGACCATCACCTCCAGGGAGATCCAGACGGCCGTGCGC
CTGCTGCTGCCAGGGGAGCTGGCCAAGCACGCGGTGTCGGAGGGCACCAAGGCCGTCACC
AAGTACACCAGTTCCAAGTGA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:4749
Chromosome Location6
LocusNot Available
References
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