NameDNA polymerase epsilon subunit 4
Synonyms
  • 2.7.7.7
  • DNA polymerase epsilon subunit p12
  • DNA polymerase II subunit 4
Gene NamePOLE4
OrganismHuman
Amino acid sequence
>lcl|BSEQ0017158|DNA polymerase epsilon subunit 4
MAAAAAAGSGTPREEEGPAGEAAASQPQAPTSVPGARLSRLPLARVKALVKADPDVTLAG
QEAIFILARAAELFVETIAKDAYCCAQQGKRKTLQRRDLDNAIEAVDEFAFLEGTLD
Number of residues117
Molecular Weight12208.63
Theoretical pI4.55
GO Classification
Functions
  • DNA binding
  • DNA-directed DNA polymerase activity
Processes
  • DNA biosynthetic process
  • histone H3 acetylation
Components
  • nucleus
  • epsilon DNA polymerase complex
  • Ada2/Gcn5/Ada3 transcription activator complex
General FunctionDna-directed dna polymerase activity
Specific FunctionMay play a role in allowing polymerase epsilon to carry out its replication and/or repair function.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein ID21411517
UniProtKB IDQ9NR33
UniProtKB Entry NameDPOE4_HUMAN
Cellular LocationNucleus
Gene sequence
>lcl|BSEQ0017159|DNA polymerase epsilon subunit 4 (POLE4)
ATGGCGGCGGCGGCGGCGGCAGGAAGCGGGACGCCCCGAGAGGAGGAGGGACCTGCTGGG
GAGGCAGCGGCCTCGCAGCCCCAGGCCCCAACGAGTGTGCCTGGGGCTCGTCTCTCGAGG
TTGCCTCTGGCGCGAGTGAAGGCCTTGGTGAAGGCAGATCCCGACGTGACGCTAGCGGGA
CAGGAAGCCATCTTCATTCTGGCACGAGCCGCGGAACTGTTTGTGGAGACCATTGCAAAA
GATGCCTACTGTTGCGCTCAGCAGGGAAAAAGGAAAACCCTTCAGAGGAGAGACTTGGAT
AATGCAATAGAAGCTGTGGATGAATTTGCTTTTCTGGAAGGTACTTTAGATTGA
GenBank Gene IDBC031331
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:18755
Chromosome Location2
Locus2p12
References
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