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NameTubulin gamma-2 chain
Synonyms
  • Gamma-2-tubulin
Gene NameTUBG2
OrganismHuman
Amino acid sequence
>lcl|BSEQ0013417|Tubulin gamma-2 chain
MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHY
IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFD
IIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPYQDEMSD
VVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAST
TTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQP
KNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVAL
SRKSPYLPSAHRVSGLMMANHTSISSLFESSCQQFDKLRKRDAFLEQFRKEDMFKDNFDE
MDRSREVVQELIDEYHAATQPDYISWGTQEQ
Number of residues451
Molecular Weight51091.32
Theoretical pINot Available
GO Classification
Functions
  • GTPase activity
  • structural molecule activity
  • GTP binding
Processes
  • G2/M transition of mitotic cell cycle
  • mitotic cell cycle
  • cytoplasmic microtubule organization
  • microtubule nucleation
Components
  • microtubule cytoskeleton
  • microtubule
  • cytosol
  • cytoplasmic microtubule
  • spindle microtubule
  • gamma-tubulin complex
  • pericentriolar material
General FunctionStructural molecule activity
Specific FunctionTubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation (By similarity).
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDQ9NRH3
UniProtKB Entry NameTBG2_HUMAN
Cellular LocationCytoplasm
Gene sequence
>lcl|BSEQ0013418|Tubulin gamma-2 chain (TUBG2)
ATGCCCCGGGAGATCATCACCCTGCAGCTGGGCCAGTGCGGCAACCAGATTGGGTTCGAG
TTCTGGAAACAGCTGTGCGCCGAGCATGGTATCAGCCCCGAGGGCATCGTGGAGGAATTC
GCCACCGAGGGCACTGACCGCAAGGACGTCTTTTTCTACCAGGCAGACGATGAGCACTAC
ATCCCCCGGGCCGTGCTGCTGGACTTGGAACCCCGGGTGATCCACTCCATCCTCAACTCC
CCCTATGCCAAGCTCTACAACCCAGAGAACATCTACCTGTCGGAACATGGAGGAGGAGCT
GGCAACAACTGGGCCAGCGGATTCTCCCAGGGTGAGAAAATTCATGAAGACATCTTTGAC
ATCATAGACCGAGAAGCAGATGGAAGTGACAGTTTGGAGGGCTTCGTGCTGTGTCACTCC
ATCGCTGGGGGTACGGGTTCTGGCCTGGGCTCCTACCTCCTGGAGCGACTGAATGACAGG
TACCCCAAGAAGCTAGTGCAGACTTATTCAGTGTTTCCCTACCAGGACGAGATGAGCGAC
GTAGTGGTTCAGCCCTACAATTCACTCCTGACACTCAAGAGGCTGACGCAGAACGCAGAT
TGTGTGGTGGTGCTGGACAACACAGCCCTGAACCGGATTGCCACAGACCGCCTGCACATC
CAGAACCCGTCCTTCTCCCAGATCAACCAGCTGGTGTCCACCATCATGTCGGCCAGCACC
ACCACCCTGCGCTACCCCGGCTACATGAACAATGACCTCATCGGCCTCATCGCCTCGCTC
ATTCCCACCCCACGGCTCCACTTCCTCATGACCGGCTACACCCCGCTCACTACAGACCAG
TCAGTGGCCAGCGTGAGGAAGACCACGGTCCTGGATGTCATGAGGCGGCTGCTGCAGCCC
AAGAACGTGATGGTGTCCACAGGCCGAGACCGCCAGACCAACCACTGCTACATCGCCATC
CTCAACATCATCCAGGGAGAGGTGGACCCCACCCAGGTCCACAAGAGCCTGCAGAGGATC
CGGGAACGGAAGTTGGCCAACTTCATCCCGTGGGGCCCCGCCAGCATCCAGGTGGCCCTG
TCGAGGAAGTCTCCCTACCTGCCCTCGGCCCACCGGGTCAGCGGGCTCATGATGGCCAAC
CACACCAGCATCTCCTCGCTCTTTGAAAGTTCCTGCCAGCAGTTTGACAAGCTGCGGAAG
CGGGATGCCTTCCTCGAGCAGTTCCGTAAGGAGGACATGTTCAAGGACAACTTTGATGAG
ATGGACAGGTCTAGGGAGGTTGTTCAGGAGCTCATTGATGAGTACCATGCGGCCACCCAG
CCAGACTACATTTCCTGGGGCACCCAGGAGCAGTGA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:12419
Chromosome Location17
LocusNot Available
References
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