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NameAspartyl aminopeptidase
Synonyms
  • 3.4.11.21
  • ASPEP
  • DAP
Gene NameDNPEP
OrganismHuman
Amino acid sequence
>lcl|BSEQ0004470|Aspartyl aminopeptidase
MQVAMNGKARKEAVQTAAKELLKFVNRSPSPFHAVAECRNRLLQAGFSELKETEKWNIKP
ESKYFMTRNSSTIIAFAVGGQYVPGNGFSLIGAHTDSPCLRVKRRSRRSQVGFQQVGVET
YGGGIWSTWFDRDLTLAGRVIVKCPTSGRLEQQLVHVERPILRIPHLAIHLQRNINENFG
PNTEMHLVPILATAIQEELEKGTPEPGPLNAVDERHHSVLMSLLCAHLGLSPKDIVEMEL
CLADTQPAVLGGAYDEFIFAPRLDNLHSCFCALQALIDSCAGPGSLATEPHVRMVTLYDN
EEVGSESAQGAQSLLTELVLRRISASCQHPTAFEEAIPKSFMISADMAHAVHPNYLDKHE
ENHRPLFHKGPVIKVNSKQRYASNAVSEALIREVANKVKVPLQDLMVRNDTPCGTTIGPI
LASRLGLRVLDLGSPQLAMHSIREMACTTGVLQTLTLFKGFFELFPSLSHNLLVD
Number of residues475
Molecular Weight52427.87
Theoretical pI7.44
GO Classification
Functions
  • zinc ion binding
  • metallopeptidase activity
  • aminopeptidase activity
Processes
  • peptide metabolic process
Components
  • cytoplasm
  • nucleus
  • nucleoplasm
  • blood microparticle
General FunctionZinc ion binding
Specific FunctionAminopeptidase with specificity towards an acidic amino acid at the N-terminus. Likely to play an important role in intracellular protein and peptide metabolism.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein ID5902181
UniProtKB IDQ9ULA0
UniProtKB Entry NameDNPEP_HUMAN
Cellular LocationCytoplasm
Gene sequence
>lcl|BSEQ0019259|Aspartyl aminopeptidase (DNPEP)
ATGAGCGGACACAGCCCCACGCGCGGGGCCATGCAGGTGGCCATGAACGGTAAGGCCCGC
AAAGAGGCGGTGCAGACTGCGGCTAAGGAACTCCTCAAGTTCGTGAACCGGAGTCCCTCT
CCTTTCCATGCTGTGGCTGAATGCCGCAACCGCCTTCTCCAGGCTGGCTTCAGTGAACTC
AAGGAGACTGAGAAATGGAATATTAAGCCCGAGAGCAAGTACTTCATGACCAGGAACTCC
TCCACCATCATAGCTTTTGCTGTAGGGGGCCAGTACGTTCCTGGCAATGGCTTCAGCCTC
ATCGGGGCCCACACGGACAGCCCCTGCCTCCGGGTGAAACGTCGGTCTCGCCGCAGCCAG
GTGGGCTTCCAGCAAGTCGGTGTGGAGACCTATGGTGGTGGGATCTGGAGCACCTGGTTT
GACCGTGACCTGACTCTGGCTGGACGCGTCATTGTCAAGTGCCCTACCTCAGGTCGGCTG
GAGCAGCAGCTGGTGCACGTGGAGCGGCCCATTCTTCGCATCCCACACCTGGCCATCCAT
CTGCAGCGAAATATCAACGAGAACTTTGGGCCCAACACAGAGATGCATCTAGTCCCCATT
CTTGCCACAGCCATCCAGGAGGAGCTGGAGAAGGGGACTCCTGAGCCAGGGCCTCTCAAT
GCTGTGGATGAGCGGCACCATTCGGTCCTCATGTCCCTGCTCTGTGCCCATCTGGGGCTG
AGCCCCAAGGACATAGTGGAGATGGAGCTCTGCCTTGCAGACACCCAGCCTGCGGTCTTG
GGTGGTGCCTATGATGAGTTCATCTTTGCTCCTCGGCTGGACAATCTGCACAGCTGCTTC
TGTGCCCTGCAGGCCTTGATAGATTCCTGTGCAGGCCCTGGCTCCCTGGCCACAGAGCCT
CACGTGCGCATGGTCACACTCTATGACAACGAAGAGGTGGGGTCTGAGAGTGCACAGGGA
GCACAGTCACTGCTGACAGAGCTGGTGCTGCGGCGGATCTCAGCCTCGTGCCAGCACCCG
ACAGCCTTCGAGGAAGCCATACCCAAGTCCTTCATGATCAGCGCAGACATGGCCCATGCT
GTGCATCCCAACTACCTGGACAAGCATGAGGAGAACCACCGGCCTTTATTCCACAAGGGC
CCCGTGATCAAGGTGAACAGCAAGCAACGCTATGCTTCAAACGCGGTGTCAGAGGCCCTG
ATCCGAGAGGTGGCCAACAAAGTCAAGGTCCCCCTGCAGGATCTCATGGTCCGGAATGAC
ACCCCCTGTGGAACCACCATTGGACCTATCTTGGCTTCTCGGCTGGGGCTGCGGGTGCTG
GATTTAGGCAGCCCCCAACTGGCCATGCACTCTATCCGGGAGATGGCCTGCACCACAGGA
GTCCTCCAGACCCTCACCCTCTTCAAGGGCTTCTTTGAGCTGTTCCCTTCTCTAAGCCAT
AATCTCTTAGTGGATTGA
GenBank Gene IDAF005050
GeneCard IDNot Available
GenAtlas IDDNPEP
HGNC IDHGNC:2981
Chromosome Location2
Locus2q35
References
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