Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4409 | Xanthine 69-89-6 | C5H4N4O2 152.111 g/mol |  |
| Xanthine is a poorly soluble compound. As a result high concentrations of serum xanthine can lead to the formation of kidney stones (xanthine kidney stones) which can...more Number of Targets: 0 |
| T3D2643 | Vipoxin Not Available | Not Available 13827.665 g/mol |  |
| Vipoxin inhibits the binding of ligands to biogenic amine receptors including dopamine,
serotonin and alpha1/alpha2 adrenergic receptors. Vipoxin also exhibits hemoly...more Number of Targets: 28 |
| T3D2642 | Viperotoxin Not Available | Not Available 15554.775 g/mol |  |
| Viperotoxin is a presynaptic neurotoxin. (T170) Number of Targets: 0 |
| T3D2496 | Versutoxin 114264-83-4 | Not Available 4855.645 g/mol |  |
| Versutoxin inhibits both insect and mammalian voltage-gated sodium channels. It binds to site 3 in tetrodotoxin-sensitive sodium channels, which slows their inactivati...more Number of Targets: 14 |
| T3D4322 | Uroporphyrin III 18273-06-8 | C40H38N4O16 830.747 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4324 | Uroporphyrin I 607-14-7 | C40H38N4O16 830.747 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4435 | Tyramine 51-67-2 | C8H11NO 137.179 g/mol |  |
| Tyramine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 4 |
| T3D4604 | Tridecanoic acid 638-53-9 | C13H26O2 214.344 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D2526 | Tityustoxin (Tityus serrulatus ) 39465-37-7 | Not Available 6997.935 g/mol |  |
| Tityustoxin binds to voltage-dependent sodium and potassium channels. alpha-Type tityustoxin inhibits the inactivation of the activated sodium channels by binding to s...more Number of Targets: 14 |
| T3D2484 | Tetrodotoxin 4368-28-9 | C11H17N3O8 319.268 g/mol |  |
| Tetrodotoxin binds to what is known as site 1 of the fast voltage-gated sodium channel. Site 1 is located at the extracellular pore opening of the ion channel. The bin...more Number of Targets: 14 |
| T3D4283 | Testosterone 58-22-0 | C19H28O2 288.424 g/mol |  |
| Testosterone is considered an anabolic steroid. It plays a key role in the development of male reproductive tissues such as the testis and prostate as well as promotin...more Number of Targets: 10 |
| T3D2525 | Tamapin 508220-81-3 | Not Available 3465.100 g/mol |  |
| Tamapin is a selective, potent, and reversible blocker of small conductance calcium-dependent potassium channels. It inhibits SK2 with the highest affinity, SK3 with a...more Number of Targets: 3 |
| T3D2585 | Taipoxin 52019-39-3 | Not Available 13828.660 g/mol |  |
| Taipoxin causes a gradual reduction to complete stop of evoked and spontaneous release of acetylcholine from motor nerve terminals. (L1106) Number of Targets: 0 |
| T3D2547 | Taicatoxin 112154-17-3 | Not Available 9711.255 g/mol |  |
| Taicatoxin blocks the voltage-dependent L-type calcium channels from the heart and on the small conductance calcium-activated potassium channels in the brain. (L1105) Number of Targets: 11 |
| T3D4466 | Sulfite 14265-45-3 | O3S 80.064 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4471 | Succinylacetone 51568-18-4 | C7H10O4 158.152 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4999 | Succinyl acetoacetate 65115-74-4 | C8H10O6 202.161 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4453 | Succinic acid 110-15-6 | C4H6O4 118.088 g/mol |  |
| Succinate can inhibit the activities of α-KG–dependent oxygenases (KDMs) and the TET family of 5-methlycytosine (5mC) hydroxylases. Succinate also mediates allosteric ...more Number of Targets: 41 |
| T3D2502 | Stromatoxin 1262235-00-6 | Not Available 3798.295 g/mol | |
| Stromatoxin blocks the delayed-rectifier type potassium channels Kv2.1, Kv2.2, Kv2.1/9.3 and the A-type potassium channel Kv4.2, with affinity (IC50) of 12.7 nM, 21.4 ...more Number of Targets: 4 |
| T3D2647 | Stonustoxin Not Available | Not Available 79523.640 g/mol | |
| Stonustoxin induces hemolytic activities due to its ability to form pores in the cell membrane. It is also myotoxic and interferes irreversibly with neuromuscular func...more Number of Targets: 0 |
| T3D2552 | Sticholysin 269658-04-0; 183449-91-4 | Not Available 19390.885 g/mol |  |
| Sticholysin is a cardiac stimulatory and hemolytic pore-forming protein. Pore formation likely proceeds by membrane binding via a surface rich in aromatic residues, fo...more Number of Targets: 0 |
| T3D4755 | Stearic acid 57-11-4 | C18H36O2 284.477 g/mol |  |
| Not Available Number of Targets: 7 |
| T3D2630 | Sphingomyelinase D (Loxosceles intermedia) 9031-54-3 | Not Available 34158.125 g/mol |  |
| Sphingomyelinase D catalyzes the hydrolysis of sphingomyelin, inducing complement-dependent haemolysis, dermonecrosis, blood vessel permeability and platelet aggregati...more Number of Targets: 0 |
| T3D2524 | Slotoxin 144026-79-9 | Not Available 4091.850 g/mol |  |
| Slotoxin reversibly blocks the high conductance calcium-activated potassium channels composed of only alpha-subunits and irreversibly blocks the high conductance calci...more Number of Targets: 3 |
| T3D4883 | Sebacic acid 111-20-6 | C10H18O4 202.248 g/mol |  |
| Not Available Number of Targets: 1 |