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Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2500 | alpha-Latrotoxin 65988-34-3 | Not Available 156855.500 g/mol |  |
| alpha-Latrotoxin acts presynaptically to release neurotransmitters from sensory and motor neurons, as well as on endocrine cells. alpha-Latrotoxin tetramers can form i...more Number of Targets: 10 |
| T3D2501 | Phrixotoxin 880886-00-0 or 221872-97-5 | Not Available 3555.310 g/mol |  |
| Phrixotoxin blocks A-type potassium channels by altering the gating properties of these channels. (T170) Number of Targets: 2 |
| T3D2502 | Stromatoxin 1262235-00-6 | Not Available 3798.295 g/mol |  |
| Stromatoxin blocks the delayed-rectifier type potassium channels Kv2.1, Kv2.2, Kv2.1/9.3 and the A-type potassium channel Kv4.2, with affinity (IC50) of 12.7 nM, 21.4 ...more Number of Targets: 4 |
| T3D2503 | Phoneutriatoxin Not Available | Not Available 12677.715 g/mol | |
| Phoneutriatoxin acts as an antagonist at certain calcium channels. (T170) Number of Targets: 3 |
| T3D2505 | Heteropodatoxin 189120-72-7 | Not Available 3917.380 g/mol |  |
| Heteropodatoxin blocks A-type, transient voltage-gated potassium channels by acting as a gating modifier. As a result, a larger depolarization is needed to open the ch...more Number of Targets: 3 |
| T3D2506 | Agitoxin 155646-21-2 | Not Available 4020.835 g/mol |  |
| Agitoxin binds to and blocks the Shaker potassium channel in Drosophila as well as to its mammalian homologue. (A157) Number of Targets: 8 |
| T3D2507 | Charybdotoxin 95751-30-7 | Not Available 6673.890 g/mol |  |
| Charybdotoxin is a neurotoxin that blocks calcium-activated and voltage gated potassium channels by binding to one of four independent, overlapping binding sites. This...more Number of Targets: 10 |
| T3D2508 | Chlorotoxin 163515-35-3 | Not Available 4004.725 g/mol |  |
| Chlorotoxin blocks small conductance chloride channels. (L1043) Number of Targets: 15 |
| T3D2509 | Cobatoxin 211688-17-4 | Not Available 7131.365 g/mol |  |
| Cobatoxin blocks calcium-activated and voltage-gated potassium channels. (L1045) Number of Targets: 7 |
| T3D2510 | alpha-Cobratoxin 769933-79-1 | Not Available 7830.960 g/mol |  |
| alpha-Cobratoxin is a muscle-type nicotinic acetylcholine receptor (nAChR) antagonist. It causes paralysis by preventing the binding of acetylcholine to the nAChR, as ...more Number of Targets: 6 |
| T3D2511 | kappa-Hefutoxin 478621-50-0 | Not Available 2659.865 g/mol |  |
| kappa-Hefutoxin blocks voltage-gated potassium channels and also slows down their activation kinetics. (L1048) Number of Targets: 2 |
| T3D2512 | Iberiotoxin 129203-60-7 | Not Available 4253.920 g/mol |  |
| Iberiotoxin binds to the outer face of the large-conductance calcium-activated potassium channels with high affinity. It selectively inhibits the current by decreasin...more Number of Targets: 5 |
| T3D2513 | Imperatoxin-A 172451-37-5 | Not Available 3764.370 g/mol |  |
| Imperatoxin-A is an activator which enhances the influx of Ca2+ from the sarcoplasmatic reticulum into the cell. Imperatoxin-A acts on the Ryanodine receptors (RyR), w...more Number of Targets: 3 |
| T3D2514 | Imperatoxin-1 Not Available | Not Available 18663.670 g/mol | |
| Imperatoxin-I is an inhibitor which decreases the influx of Ca2+ from the sarcoplasmatic reticulum into the cell. Imperatoxin-I acts on the Ryanodine receptors (RyR), ...more Number of Targets: 3 |
| T3D2515 | Kaliotoxin 145199-73-1 | Not Available 6461.905 g/mol |  |
| Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. It binds to the extracellular surface and blocks the channel, affectin...more Number of Targets: 6 |
| T3D2516 | Kaliotoxin-1 150769-72-5 | Not Available 4155.975 g/mol |  |
| Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. It binds to the extracellular surface and blocks the channel, affectin...more Number of Targets: 6 |
| T3D2517 | Kaliotoxin-2 159605-22-8 | Not Available 6392.840 g/mol | |
| Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. It binds to the extracellular surface and blocks the channel, affectin...more Number of Targets: 6 |
| T3D2518 | Kaliotoxin-3 223246-26-2 | Not Available 4027.840 g/mol | |
| Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. It binds to the extracellular surface and blocks the channel, affectin...more Number of Targets: 6 |
| T3D2519 | Kurtoxin 820959-57-7 | Not Available 7394.400 g/mol |  |
| Kurtoxin affects the gating of voltage-gated sodium channels and calcium channels. In calcium channels Kurtoxin binds close to the channel voltage sensor and thereby p...more Number of Targets: 14 |
| T3D2520 | Margatoxin 145808-47-5 | Not Available 4184.990 g/mol |  |
| Margatoxin blocks potassium channels, resulting in a loss of outward current and affecting neurotransmitter release. (L1057) Number of Targets: 1 |
| T3D2521 | Maurotoxin 188240-41-7 | Not Available 3621.205 g/mol |  |
| Maurotoxin acts by blocking several types of voltage-gated potassium channel. (L1059) Number of Targets: 7 |
| T3D2522 | Noxiustoxin 85205-49-8 | Not Available 4201.920 g/mol |  |
| Noxiustoxin blocks voltage-gated non-inactivating potassium channels and unblocks inactivating potassium channels blocked by alpha-dendrotoxin in synaptosomes. It also...more Number of Targets: 23 |
| T3D2523 | Scyllatoxin 142948-19-4 | Not Available 3430.130 g/mol |  |
| Scyllatoxin blocks small conductance calcium-activated potassium channels. This inhibits the slow after-hyperpolarisation that follows an action potential in some nerv...more Number of Targets: 3 |
| T3D2524 | Slotoxin 144026-79-9 | Not Available 4091.850 g/mol |  |
| Slotoxin reversibly blocks the high conductance calcium-activated potassium channels composed of only alpha-subunits and irreversibly blocks the high conductance calci...more Number of Targets: 3 |
| T3D2525 | Tamapin 508220-81-3 | Not Available 3465.100 g/mol |  |
| Tamapin is a selective, potent, and reversible blocker of small conductance calcium-dependent potassium channels. It inhibits SK2 with the highest affinity, SK3 with a...more Number of Targets: 3 |