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Browsing Toxins By Category
T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
---|---|---|---|---|---|
T3D2643 | Vipoxin Not Available | Not Available 13827.665 g/mol |
| Vipoxin inhibits the binding of ligands to biogenic amine receptors including dopamine,
serotonin and alpha1/alpha2 adrenergic receptors. Vipoxin also exhibits hemoly...more Number of Targets: 28 | |
T3D2645 | Brevetoxin 98112-41-5 | C49H68O14 881.056 g/mol |
| Brevetoxins are neurotoxins that bind to voltage-gated sodium channels in nerve cells, leading to disruption of normal neurological processes. (L1112) Number of Targets: 14 | |
T3D2646 | Hydralysin (Chlorohydra viridissima) Not Available | Not Available 26212.075 g/mol |
| Hydralysin is a cytolytic toxin. It binds to erythrocyte membranes and has weak hemolytic activity, probably mediated by oligomerization and pore formation. (T170) Number of Targets: 0 | |
T3D2647 | Stonustoxin Not Available | Not Available 79523.640 g/mol |
| Stonustoxin induces hemolytic activities due to its ability to form pores in the cell membrane. It is also myotoxic and interferes irreversibly with neuromuscular func...more Number of Targets: 0 | |
T3D2648 | Neoverrucotoxin Not Available | Not Available 79669.850 g/mol |
| Neoverrucotoxin has hemolytic activities. (T170) Number of Targets: 0 | |
T3D2649 | Box jellyfish toxin (Chironex fleckeri) Not Available | Not Available 51389.865 g/mol |
| Box jellyfish toxin has potent hemolytic activity and may act as a pore-forming toxin, disrupting normal transmembrane ion concentration gradients in susceptible cells...more Number of Targets: 0 | |
T3D2656 | omega-Conotoxin (Conus striatus) Not Available | Not Available 7628.040 g/mol |
| omega-Conotoxins act at presynaptic membranes, where they bind inhibit N-type voltage-dependent calcium channels. (L1107) Number of Targets: 1 | |
T3D2657 | alpha-Conotoxin (Conus geographus) Not Available | Not Available 1627.830 g/mol |
| alpha-Conotoxins act on postsynaptic membranes, where they inhibit nicotinic acetylcholine receptors in nerves and muscles. (L1107) Number of Targets: 15 | |
T3D2658 | delta-Conotoxin (Conus striatus) Not Available | Not Available 9216.755 g/mol |
| delta-Conotoxins inhibit the inactivation of voltage-dependent sodium channels. (L1107) Number of Targets: 14 | |
T3D2659 | kappa-Conotoxin (Conus purpurascens) Not Available | Not Available 8316.795 g/mol |
| kappa-Conotoxins inhibit potassium channels. (L1107) Number of Targets: 23 | |
T3D2660 | mu-Conotoxin (Conus purpurascens) Not Available | Not Available 8333.700 g/mol |
| mu-Conotoxins inhibit voltage-dependent sodium channels in muscles. (L1107) Number of Targets: 14 | |
T3D2661 | Contryphan (Conus ventricosus) Not Available | Not Available 1091.260 g/mol |
| Contryphan affects both voltage-gated and calcium-dependent potassium channels. (L1108) Number of Targets: 32 | |
T3D2671 | Rituximab 174722-31-7 | Not Available 36105.695 g/mol |
| Binds to the CD20 antigen which is found on mature B lymphocytes. The Fc domain recruits immune effector functions to mediate B-cell lysis. The antibody appears to ind...more Number of Targets: 12 | |
T3D2672 | Azaspiracid 214899-21-5 | C47H71NO12 842.066 g/mol |
| Azaspiracid-4 dose-dependent inhibits the increase in cytosolic Ca2+ levels induced by thapsigargin (Tg) (A330). Azaspiracid-2 and Azaspiracid-3 clearly increase cytos...more Number of Targets: 1 | |
T3D2690 | Biotin 58-85-5 | C10H16N2O3S 244.311 g/mol |
| Biotin is necessary for the proper functioning of enzymes that transport carboxyl units and fix carbon dioxide, and is required for various metabolic functions, includ...more Number of Targets: 10 | |
T3D2702 | (R)-lipoic acid 62-46-4 | C8H14O2S2 206.326 g/mol |
| (R)-lipoic acid is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholi...more Number of Targets: 6 | |
T3D2972 | Melatonin 73-31-4 | C13H16N2O2 232.278 g/mol |
| Melatonin is a derivative of tryptophan. It binds to melatonin receptor type 1A, which then acts on adenylate cylcase and the inhibition of a cAMP signal transduction ...more Number of Targets: 18 | |
T3D3233 | CE(10:0) 1183-04-6 | C37H64O2 540.903 g/mol |
| Not Available Number of Targets: 2 | |
T3D3241 | Diacetyl 431-03-8 | C4H6O2 86.089 g/mol |
| Diacetyl is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 4 | |
T3D3514 | Infliximab 170277-31-3 | Not Available 36105.695 g/mol |
| Infliximab neutralizes the biological activity of TNFa by binding with high affinity to the soluble and transmembrane forms of TNFa and inhibits binding of TNFa with i...more Number of Targets: 3 | |
T3D3956 | Cotinine 486-56-6 | C10H12N2O 176.215 g/mol |
| Not Available Number of Targets: 1 | |
T3D3958 | Diethylthiophosphate 5871-17-0 | C4H11O3PS 170.167 g/mol |
| Diethylthiophosphate (DETP) induces DNA damage only in the hepatic cell lines, and this effect could be related to a secondary non-diffusible metabolite generated by t...more Number of Targets: 1 | |
T3D3960 | Monoisobutyl phthalic acid 30833-53-5 | C12H14O4 222.237 g/mol |
| Phthalates are synthetic industrial compounds capable of disrupting the endocrine system. The phthalates have been the most common chemical compounds with the ability ...more Number of Targets: 4 | |
T3D3961 | Monoethyl phthalate 2306-33-4 | C10H10O4 194.184 g/mol |
| Not Available Number of Targets: 3 | |
T3D3962 | Equol 531-95-3 | C15H14O3 242.270 g/mol |
| Not Available Number of Targets: 2 |