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Displaying toxin 26 - 50 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D0235(±)-Naled
300-76-5
C4H7Br2Cl2O4P
380.784 g/mol
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  • Bromide Compound
  • Ester
  • Food Toxin
  • Metabolite
  • Organic Compound
  • Organobromide
  • Organochloride
  • Organophosphate
  • Pesticide
  • Synthetic Compound
(±)-Naled is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinester...more
Number of Targets: 11
T3D16871,1'-Azobis(cyclohexanecarbonitrile)
2094-98-6
C14H20N4
244.335 g/mol
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  • Cyanide Compound
  • Industrial/Workplace Toxin
  • Nitrile
  • Organic Compound
  • Synthetic Compound
Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more
Number of Targets: 39
T3D00971,1,1-Trichloroethane
71-55-6
C2H3Cl3
133.404 g/mol
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  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Organochloride
  • Pollutant
  • Solvent
  • Synthetic Compound
1,1,1-Trichloroethane is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acety...more
Number of Targets: 41
T3D18041,1,2,2-Tetrabromoethane
79-27-6
C2H2Br4
345.653 g/mol
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  • Bromide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Synthetic Compound
Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more
Number of Targets: 0
T3D01461,1,2,2-Tetrachloroethane
79-34-5
C2H2Cl4
167.849 g/mol
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  • Food Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Refrigerant
  • Solvent
  • Synthetic Compound
The presence of the functional group consisting of a terminal dichloromethyl moiety in a molecule is known to confer toxicity. Moreover, the metabolism of 1,1,2,2-tetr...more
Number of Targets: 39
T3D01631,1,2-Trichloroethane
79-00-5
C2H3Cl3
133.404 g/mol
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  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pollutant
  • Solvent
  • Synthetic Compound
Acyl chlorides and free radicals formed during the metabolism of 1,1,2-trichloroethane are reactive metabolites that can bind to proteins and nucleic acids (DNA, RNA),...more
Number of Targets: 5
T3D17931,1-Dibromoethane
557-91-5
C2H4Br2
187.861 g/mol
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  • Bromide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Synthetic Compound
Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more
Number of Targets: 0
T3D01601,1-Dichloroethane
75-34-3
C2H4Cl2
98.959 g/mol
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  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Solvent
  • Synthetic Compound
The limited information available about 1,1-dichloroethane suggests that it may be nephrotoxic, fetotoxic, and possibly carcinogenic. 1,1-Dichloroethane has been obser...more
Number of Targets: 40
T3D00791,1-Dichloroethene
75-35-4
C2H2Cl2
96.943 g/mol
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  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
1,1-Dichloroethene toxicity is caused by its reactive metabolites, which include epoxides, acyl chlorides, and halogenated aldehydes generated via oxidation by cytochr...more
Number of Targets: 39
T3D19081,1-Dichloropropene
563-58-6
C3H4Cl2
110.970 g/mol
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  • Chloropropene
  • Food Toxin
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
The primary toxic effects of 1,1-dichloropropene are portal-of-entry effects resulting from the chemical reactivity of the compound and its physicochemical properties....more
Number of Targets: 3
T3D35221,1-Dimethylbiguanide
657-24-9
C4H11N5
129.164 g/mol
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  • Amide
  • Amine
  • Antidiabetic Agent
  • Drug
  • Food Toxin
  • Hypoglycemic Agent
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Metformin's mechanisms of action differ from other classes of oral antihyperglycemic agents. Metformin decreases blood glucose levels by decreasing hepatic glucose pro...more
Number of Targets: 4
T3D48151,10-Phenanthroline
66-71-7
C12H8N2
180.205 g/mol
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  • Industrial/Workplace Toxin
  • Organic Compound
  • Synthetic Compound
Not Available
Number of Targets: 6
T3D21321,2,3,4,6,7,8,9,10,10,11,11-Dodecachloro-1,4,4a,5a,6,9,9a,9b-octahydro-1,4:6,9- dimethanodibenzofuran
31107-44-5
C14H5Cl11O
579.172 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D01621,2,3,4,6,7,8,9-Octachlorodibenzofuran
39001-02-0
C12Cl8O
443.752 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D21341,2,3,4,6,7,8-Heptabromodibenzofuran
107555-95-3
C12HBr7O
720.464 g/mol
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  • Aromatic Hydrocarbon
  • Bromide Compound
  • Brominated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organobromide
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D21161,2,3,4,6,7,8-Heptachlorodibenzo-p-dioxin
35822-46-9
C12HCl7O2
425.306 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzo-p-dioxin
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the transcription of certain genes. The affinity for the Ah recept...more
Number of Targets: 3
T3D01661,2,3,4,6,7,8-Heptachlorodibenzofuran
38998-75-3
C12HCl7O
409.307 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D21171,2,3,4,6,7,9-Heptachlorodibenzo-p-dioxin
58200-70-7
C12HCl7O2
425.306 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzo-p-dioxin
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the transcription of certain genes. The affinity for the Ah recept...more
Number of Targets: 3
T3D21361,2,3,4,6,7,9-Heptachlorodibenzofuran
70648-25-8
C12HCl7O
409.307 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D23581,2,3,4,6,7-Hexabromo-8,9-dichlorodibenzofuran
107207-36-3
C12Br6Cl2O
710.458 g/mol
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  • Aromatic Hydrocarbon
  • Bromide Compound
  • Brominated Dibenzofuran
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organobromide
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D21371,2,3,4,6,7-Hexabromodibenzofuran
124388-78-9
C12H2Br6O
641.568 g/mol
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  • Aromatic Hydrocarbon
  • Bromide Compound
  • Brominated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organobromide
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D21101,2,3,4,6,7-Hexachlorodibenzo-p-dioxin
58200-66-1
C12H2Cl6O2
390.861 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzo-p-dioxin
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the transcription of certain genes. The affinity for the Ah recept...more
Number of Targets: 3
T3D21381,2,3,4,6,7-Hexachlorodibenzofuran
79060-60-9
C12H2Cl6O
374.862 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D21391,2,3,4,6,8,9-Heptachlorodibenzofuran
69698-58-4
C12HCl7O
409.307 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D21151,2,3,4,6,8-Hexachlorodibenzo-p-dioxin
58200-67-2
C12H2Cl6O2
390.861 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Chlorinated Dibenzo-p-dioxin
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the transcription of certain genes. The affinity for the Ah recept...more
Number of Targets: 3
Displaying toxin 26 - 50 of 3678 in total