Tmic
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Displaying toxins 1 - 25 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D3602Microcystin-LR
101043-37-2
Not Available
Not Available
T3d3602
  • Amide
  • Amine
  • Bacterial Toxin
  • Ether
  • Microcystin
  • Natural Compound
  • Organic Compound
  • Protein
The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more
Number of Targets: 24
T3D0065Chromium(VI) oxide
1333-82-0
CrO3
99.994 g/mol
Thumb
  • Chromium Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Pollutant
  • Synthetic Compound
Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more
Number of Targets: 5
T3D2413Sodium phosphide
12058-85-4
Na3P
99.943 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Phosphide
  • Synthetic Compound
Phosphine inhibits cytochrome c oxidase, preventing mitochondrial oxidative phosphorylation. This non-competitive inhibition prevents cellular respiration and leads to...more
Number of Targets: 20
T3D0731Zinc hydroxide
20427-58-1
H2O2Zn
99.424 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Synthetic Compound
  • Zinc Compound
Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more
Number of Targets: 1
T3D0737Zinc peroxide
1314-22-3
H2O2Zn
99.424 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Lachrymator
  • Synthetic Compound
  • Zinc Compound
Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more
Number of Targets: 2
T3D0769Trimethylsilyl cyanide
7677-24-9
C4H9NSi
99.207 g/mol
Thumb
  • Cyanide Compound
  • Industrial/Workplace Toxin
  • Nitrile
  • Organic Compound
  • Organometallic
  • Pollutant
  • Synthetic Compound
Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more
Number of Targets: 39
T3D0778Allyl isothiocyanate
57-06-7
C4H5NS
99.154 g/mol
Thumb
  • Cyanide Compound
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Pesticide
  • Pollutant
  • Synthetic Compound
Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more
Number of Targets: 41
T3D1666n-Butyl isocyanate
111-36-4
C5H9NO
99.131 g/mol
Thumb
  • Cyanide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Pollutant
  • Synthetic Compound
Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more
Number of Targets: 39
T3D49461-Methyl-2-pyrrolidone
872-50-4
C5H9NO
99.131 g/mol
Thumb
  • Amide
  • Amine
  • Household Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Solvent
  • Synthetic Compound
Not Available
Number of Targets: 1
T3D3611Microcystin-LF
154037-70-4
C52H71N7O12
986.160 g/mol
Thumb
  • Amide
  • Amine
  • Bacterial Toxin
  • Ether
  • Microcystin
  • Natural Compound
  • Organic Compound
The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more
Number of Targets: 23
T3D1201Copper(I) chloride
7758-89-6
ClCu
98.999 g/mol
Thumb
  • Copper Compound
  • Inorganic Compound
  • Natural Compound
  • Pesticide
Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more
Number of Targets: 6
T3D00851,2-Dichloroethane
107-06-2
C2H4Cl2
98.959 g/mol
Thumb
  • Food Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Organochloride
  • Pollutant
  • Solvent
  • Synthetic Compound
1,2-Dichloroethane is metabolized to 2-chloroacetaldehyde, S-(2-chloroethyl)glutathione by conjugation with glutathione, and to other putative reactive intermediates c...more
Number of Targets: 39
T3D01601,1-Dichloroethane
75-34-3
C2H4Cl2
98.959 g/mol
Thumb
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Solvent
  • Synthetic Compound
The limited information available about 1,1-dichloroethane suggests that it may be nephrotoxic, fetotoxic, and possibly carcinogenic. 1,1-Dichloroethane has been obser...more
Number of Targets: 40
T3D48944-Methyl-3-penten-2-one, 9CI
141-79-7
C6H10O
98.143 g/mol
Thumb
  • Ester
  • Flavouring Agent
  • Food Toxin
  • Household Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Not Available
Number of Targets: 2
T3D41892-Hexenal
505-57-7
C6H10O
98.143 g/mol
Thumb
  • Aldehyde
  • Ester
  • Flavouring Agent
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Uremic Toxin
Uremic toxins such as 2-Hexenal are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimula...more
Number of Targets: 4
T3D5000Sulfuric acid
7664-93-9
H2O4S
98.078 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Natural Compound
  • Non-Metal
Many strong acids cause tissue burns through the denaturation of proteins and partial hydrolysis of proteins. Most proteins denature at pH values of less than 3-4. T...more
Number of Targets: 0
T3D3770Moniliformin
71376-34-6
C4H2O3
98.057 g/mol
Thumb
  • Carbamate
  • Food Toxin
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Moniliformin reversibly inhibits the enzymes pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase by competing for the binding site of pyruvate. This interfere...more
Number of Targets: 7
T3D4760Alpha-Cyclodextrin (Cyclohexa-Amylose)
10016-20-3
C36H60O30
972.844 g/mol
Thumb
  • Food Toxin
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Not Available
Number of Targets: 2
T3D4896Phosphoric acid
7664-38-2
H3O4P
97.995 g/mol
Thumb
  • Food Additive
  • Food Toxin
  • Household Toxin
  • Inorganic Compound
  • Metabolite
  • Non-Metal
  • Synthetic Compound
Not Available
Number of Targets: 1
T3D1721Ammonium bromide
12124-97-9
BrH4N
97.942 g/mol
Thumb
  • Bromide Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Non-Metal
  • Synthetic Compound
Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more
Number of Targets: 6
T3D0678Lithium cobalt oxide
12190-79-3
CoLiO2
97.873 g/mol
Thumb
  • Amide
  • Amine
  • Cobalt Compound
  • Ether
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more
Number of Targets: 35
T3D1211Copper(II) hydroxide
20427-59-2
CuH2O2
97.561 g/mol
Thumb
  • Copper Compound
  • Inorganic Compound
  • Natural Compound
  • Pesticide
Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more
Number of Targets: 6
T3D0745Zinc sulfide
1314-98-3
SZn
97.474 g/mol
Thumb
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Natural Compound
  • Zinc Compound
Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more
Number of Targets: 1
T3D3557Chlorine nitrate
14545-72-3
ClNO3
97.458 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Nitrate
  • Nitrite
  • Non-Metal
  • Synthetic Compound
Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more
Number of Targets: 9
T3D00791,1-Dichloroethene
75-35-4
C2H2Cl2
96.943 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
1,1-Dichloroethene toxicity is caused by its reactive metabolites, which include epoxides, acyl chlorides, and halogenated aldehydes generated via oxidation by cytochr...more
Number of Targets: 39
Displaying toxins 1 - 25 of 3678 in total