Tmic
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Displaying toxins 26 - 50 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D0173trans-1,2-Dichloroethene
156-60-5
C2H2Cl2
96.943 g/mol
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  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pollutant
  • Solvent
  • Synthetic Compound
Trans-1,2-dichloroethene is a volatile, lipophilic molecule that easily moves through the respiratory and gastrointestinal systems. It has a high affinity for lipids a...more
Number of Targets: 4
T3D0660Cobalt(II) fluoride
10026-17-2
CoF2
96.930 g/mol
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  • Cobalt Compound
  • Fluoride Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Pollutant
  • Synthetic Compound
Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more
Number of Targets: 35
T3D0692Nickel fluoride
10028-18-9
F2Ni
96.690 g/mol
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  • Fluoride Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Nickel Compound
  • Pollutant
  • Synthetic Compound
Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more
Number of Targets: 68
T3D39822,5-Dimethylfuran
625-86-5
C6H8O
96.127 g/mol
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  • Food Toxin
  • Fuel
  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Synthetic Compound
2,5-Dimethylfuran plays a role in the mechanism for the neurotoxicity of hexane in humans. Together with hexane-2,5-dione and 4,5-dihydroxy-2-hexanone, it is one of th...more
Number of Targets: 0
T3D3562Hydroxylammonium nitrate
13465-08-2
H4N2O4
96.043 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Nitrate
  • Nitrite
  • Non-Metal
  • Synthetic Compound
Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more
Number of Targets: 9
T3D20452,2',3,3',4,4',5,5',6,6'-Decabromobiphenyl Ether
1163-19-5
C12Br10O
959.168 g/mol
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  • Aromatic Hydrocarbon
  • Bromide Compound
  • Ether
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
Like other halogenated aromatic hydrocarbons, polybrominated diphenyl ethers bind to the cellular aryl hydrocarbon receptor (AhR), which regulates the synthesis of a v...more
Number of Targets: 6
T3D3613Microcystin-LL
154037-67-9
C49H73N7O12
952.144 g/mol
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  • Amide
  • Amine
  • Bacterial Toxin
  • Ether
  • Microcystin
  • Natural Compound
  • Organic Compound
The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more
Number of Targets: 23
T3D3957Molybdenum
7439-98-7
Mo
95.940 g/mol
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  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Metal
  • Natural Compound
High levels of molybdenum can interfere with the body's uptake of copper, producing copper deficiency. Molybdenum prevents plasma proteins from binding to copper, and ...more
Number of Targets: 1
T3D1198Copper(II) sulfide
1317-40-4
CuS
95.611 g/mol
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  • Copper Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Natural Compound
Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more
Number of Targets: 6
T3D0749Dimethylzinc
544-97-8
C2H6Zn
95.478 g/mol
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  • Industrial/Workplace Toxin
  • Organic Compound
  • Organometallic
  • Synthetic Compound
  • Zinc Compound
Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more
Number of Targets: 1
T3D1654Trifluoromethyl isocyanide
105879-13-8
C2F3N
95.023 g/mol
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  • Cyanide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organofluoride
  • Pollutant
  • Synthetic Compound
Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more
Number of Targets: 39
T3D19402,2',3,3',4,4',5,5',6,6'-Decabromobiphenyl
13654-09-6
C12Br10
943.168 g/mol
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  • Aromatic Hydrocarbon
  • Bromide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more
Number of Targets: 1
T3D1787Bromomethane
74-83-9
CH3Br
94.939 g/mol
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  • Bromide Compound
  • Food Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Organobromide
  • Pesticide
  • Pollutant
  • Synthetic Compound
Organobromide compounds such as bromomethane are strong alkylating agents. Consequently they can readily modify free thiols (cysteines) and methionine residues of the...more
Number of Targets: 3
T3D25534-Aminopyridine
504-24-5
C5H6N2
94.115 g/mol
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  • Amine
  • Drug
  • Industrial Precursor/Intermediate
  • Organic Compound
  • Potassium Channel Blocker
  • Synthetic Compound
4-Aminopyridine blocks potassium channels and thereby increases acetylcholine, and possibly noradrenaline, release at nerve terminals (A316). In MS, axons are progress...more
Number of Targets: 17
T3D1703Glutaronitrile
544-13-8
C5H6N2
94.115 g/mol
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  • Cyanide Compound
  • Industrial/Workplace Toxin
  • Nitrile
  • Organic Compound
  • Synthetic Compound
Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more
Number of Targets: 39
T3D0182Phenol
108-95-2
C6H6O
94.111 g/mol
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  • Anti-Infective Agent, Local
  • Antipsoriatic Agent
  • Antiseptic Agent
  • Aromatic Hydrocarbon
  • Disinfectant
  • Drug
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Pollutant
  • Sclerosing Solution
Phenol is irritating and corrosive at high concentrations. Phenol impairs the stratum corneum and produces coagulation necrosis by denaturing and precipitating protein...more
Number of Targets: 13
T3D3570Methylammonium nitrate
22113-87-7
CH6N2O3
94.070 g/mol
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  • Amine
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Nitrate
  • Organic Compound
  • Synthetic Compound
Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more
Number of Targets: 9
T3D4984Aniline
62-53-3
C6H7N
93.127 g/mol
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  • Carcinogen
  • Dye
  • Industrial/Workplace Toxin
  • Metabolite
  • Synthetic Compound
Aniline induces lipid peroxidation and protein oxidation in the spleen and that oxidative stress plays a role in the splenic toxicity of aniline. The hematopoietic sys...more
Number of Targets: 2
T3D2847Nystatin
1400-61-9
C47H75NO17
926.095 g/mol
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  • Amine
  • Anti-Bacterial Agent
  • Antifungal Agent
  • Drug
  • Ester
  • Ionophore
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Nystatin interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary for the conversion of lanosterol to ergosterol. This results in inhibition of ergosterol ...more
Number of Targets: 0
T3D0662Cobalt(II) hydroxide
21041-93-0
CoH2O2
92.948 g/mol
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  • Cobalt Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Pollutant
  • Synthetic Compound
Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more
Number of Targets: 35
T3D1146Manganese fluoride
7782-64-1
F2Mn
92.935 g/mol
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  • Fluoride Compound
  • Food Toxin
  • Inorganic Compound
  • Manganese Compound
  • Pollutant
  • Synthetic Compound
Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particu...more
Number of Targets: 5
T3D0693Nickel hydroxide
12054-48-7
H2NiO2
92.708 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Natural Compound
  • Nickel Compound
  • Pollutant
Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more
Number of Targets: 68
T3D4662Chloracetone
78-95-5
C3H5ClO
92.524 g/mol
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  • Insecticide
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Not Available
Number of Targets: 1
T3D0071Toluene
108-88-3
C7H8
92.138 g/mol
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  • Aromatic Hydrocarbon
  • Cosmetic Toxin
  • Food Toxin
  • Household Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Pollutant
  • Solvent
Toluene is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinesteras...more
Number of Targets: 39
T3D0759Calcium cyanide
592-01-8
C2CaN2
92.113 g/mol
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  • Cyanide Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Nitrile
  • Organic Compound
  • Pollutant
  • Synthetic Compound
Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more
Number of Targets: 42
Displaying toxins 26 - 50 of 3678 in total