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Displaying toxin 26 - 50 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D2566Heparin
9005-49-6
C26H41NO34S4
1039.850 g/mol
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  • Animal Toxin
  • Anticoagulant
  • Drug
  • Ester
  • Fibrinolytic Agent
  • Food Toxin
  • Heparin
  • Metabolite
  • Natural Compound
  • Organic Compound
Heparin-induced thrombocytopenia (HIT) is caused by the formation of abnormal antibodies that activate platelets. Heparin occurs naturally in the human body, but the d...more
Number of Targets: 14
T3D3609Microcystin-RR
111755-37-4
C49H75N13O12
1038.200 g/mol
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  • Amide
  • Amine
  • Bacterial Toxin
  • Ether
  • Microcystin
  • Natural Compound
  • Organic Compound
The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more
Number of Targets: 23
T3D3614Microcystin-LW
157622-02-1
C54H72N8O12
1025.196 g/mol
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  • Amide
  • Amine
  • Bacterial Toxin
  • Ether
  • Microcystin
  • Natural Compound
  • Organic Compound
The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more
Number of Targets: 23
T3D1219Copper(II) acetoarsenite
12002-03-8
C4H6As6Cu4O16
1013.794 g/mol
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  • Arsenic Compound
  • Copper Compound
  • Organic Compound
  • Organometallic
  • Pesticide
  • Synthetic Compound
Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more
Number of Targets: 49
T3D3831Emamectin benzoate
155569-91-8
C56H81NO15
1008.240 g/mol
Thumb
  • Insecticide
  • Pesticide
  • Synthetic Compound
Not Available
Number of Targets: 40
T3D3615Microcystin-LY
123304-10-9
C52H71N7O13
1002.159 g/mol
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  • Amide
  • Amine
  • Bacterial Toxin
  • Ether
  • Microcystin
  • Natural Compound
  • Organic Compound
The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more
Number of Targets: 23
T3D3602Microcystin-LR
101043-37-2
Not Available
Not Available
T3d3602
  • Amide
  • Amine
  • Bacterial Toxin
  • Ether
  • Microcystin
  • Natural Compound
  • Organic Compound
  • Protein
The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more
Number of Targets: 24
T3D3611Microcystin-LF
154037-70-4
C52H71N7O12
986.160 g/mol
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  • Amide
  • Amine
  • Bacterial Toxin
  • Ether
  • Microcystin
  • Natural Compound
  • Organic Compound
The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more
Number of Targets: 23
T3D4760Alpha-Cyclodextrin (Cyclohexa-Amylose)
10016-20-3
C36H60O30
972.844 g/mol
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  • Food Toxin
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Not Available
Number of Targets: 2
T3D20452,2',3,3',4,4',5,5',6,6'-Decabromobiphenyl Ether
1163-19-5
C12Br10O
959.168 g/mol
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  • Aromatic Hydrocarbon
  • Bromide Compound
  • Ether
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
Like other halogenated aromatic hydrocarbons, polybrominated diphenyl ethers bind to the cellular aryl hydrocarbon receptor (AhR), which regulates the synthesis of a v...more
Number of Targets: 6
T3D3613Microcystin-LL
154037-67-9
C49H73N7O12
952.144 g/mol
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  • Amide
  • Amine
  • Bacterial Toxin
  • Ether
  • Microcystin
  • Natural Compound
  • Organic Compound
The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more
Number of Targets: 23
T3D19402,2',3,3',4,4',5,5',6,6'-Decabromobiphenyl
13654-09-6
C12Br10
943.168 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Bromide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more
Number of Targets: 1
T3D2847Nystatin
1400-61-9
C47H75NO17
926.095 g/mol
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  • Amine
  • Anti-Bacterial Agent
  • Antifungal Agent
  • Drug
  • Ester
  • Ionophore
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Nystatin interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary for the conversion of lanosterol to ergosterol. This results in inhibition of ergosterol ...more
Number of Targets: 0
T3D3585beta-Amanitin
21150-22-1
Not Available
3445.915 g/mol
T3d3585
  • Amide
  • Amine
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
  • Protein
The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in the synthesis of messenger RNA (mRNA), microRNA, and small nuclear RNA...more
Number of Targets: 14
T3D2450alpha-Amanitin
23109-05-9
C39H54N10O14S
918.970 g/mol
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  • Amide
  • Amine
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
  • Protein
Amanitin has an unusually strong and specific attraction to the enzyme RNA polymerase II. Upon ingestion, it binds to the RNA polymerase II enzyme, preventing mRNA syn...more
Number of Targets: 14
T3D2921Sirolimus
53123-88-9
C51H79NO13
914.172 g/mol
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  • Amide
  • Amine
  • Anti-Bacterial Agent
  • Antibiotic, Antineoplastic
  • Antifungal Agent
  • Drug
  • Ester
  • Ether
  • Immunosuppressive Agent
  • Macrolide
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Sirolimus inhibits T lymphocyte activation and proliferation that occurs in response to antigenic and cytokine (Interleukin IL-2, IL-4, and IL-15) stimulation by a mec...more
Number of Targets: 4
T3D3610Cyanoginosin-LA
96180-79-9
C46H67N7O12
910.064 g/mol
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  • Amide
  • Amine
  • Bacterial Toxin
  • Ether
  • Microcystin
  • Natural Compound
  • Organic Compound
The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more
Number of Targets: 23
T3D3591Amanin
21150-21-0
C39H53N9O14S
903.955 g/mol
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  • Amide
  • Amine
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in the synthesis of messenger RNA (mRNA), microRNA, and small nuclear RNA...more
Number of Targets: 14
T3D3587epsilon-Amanitin
21705-02-2
C39H53N9O14S
903.955 g/mol
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  • Amide
  • Amine
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in the synthesis of messenger RNA (mRNA), microRNA, and small nuclear RNA...more
Number of Targets: 14
T3D3590Amaninamide
58311-65-2
C39H54N10O13S
902.970 g/mol
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  • Amide
  • Amine
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in the synthesis of messenger RNA (mRNA), microRNA, and small nuclear RNA...more
Number of Targets: 14
T3D3586gamma-Amanitin
21150-23-2
Not Available
3706.230 g/mol
T3d3586
  • Amide
  • Amine
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
  • Protein
The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in the synthesis of messenger RNA (mRNA), microRNA, and small nuclear RNA...more
Number of Targets: 14
T3D4128Brevetoxin B
79580-28-2
C50H70O14
895.082 g/mol
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  • Aldehyde
  • Animal Toxin
  • Ester
  • Ether
  • Marine Toxin
  • Natural Compound
  • Organic Compound
Brevetoxins are neurotoxins that bind to voltage-gated sodium channels in nerve cells, leading to disruption of normal neurological processes and causing the illness c...more
Number of Targets: 1
T3D2538beta-Bungarotoxin
12778-32-4
Not Available
9571.020 g/mol
T3d2538
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
beta-Bungarotoxin acts at the presynaptic terminal, where it causes release of acetylcholine and subsequent exhaustion of acetylcholine stores in the nerve terminal by...more
Number of Targets: 23
T3D2537alpha-Bungarotoxin
11032-79-4
Not Available
10285.030 g/mol
T3d2537
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
alpha-Bungarotoxin binds irreversibly and competitively to muscular and neuronal nicotinic acetylcholine receptors. This produces peripheral paralysis by blocking neur...more
Number of Targets: 8
T3D3589Amanullinic acid
54532-45-5
C39H53N9O13S
887.956 g/mol
Thumb
  • Amide
  • Amine
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in the synthesis of messenger RNA (mRNA), microRNA, and small nuclear RNA...more
Number of Targets: 14
Displaying toxin 26 - 50 of 3678 in total