Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2042 | Heptabromobiphenyl Ether 68928-80-3 | C12H3Br7O 722.480 g/mol |  |
| Like other halogenated aromatic hydrocarbons, polybrominated diphenyl ethers bind to the cellular aryl hydrocarbon receptor (AhR), which regulates the synthesis of a v...more Number of Targets: 6 |
| T3D3603 | Fumonisin B1 116355-83-0 | C34H59NO15 721.830 g/mol |  |
| Fumonisins are similar in structure to the long-chain base backbones of sphingolipids, allowing it to inhibit of the biosynthesis of sphingosine and more complex sphin...more Number of Targets: 16 |
| T3D2143 | 1,2,3,4,7,8,9-Heptabromodibenzofuran 161880-51-9 | C12HBr7O 720.464 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2134 | 1,2,3,4,6,7,8-Heptabromodibenzofuran 107555-95-3 | C12HBr7O 720.464 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2358 | 1,2,3,4,6,7-Hexabromo-8,9-dichlorodibenzofuran 107207-36-3 | C12Br6Cl2O 710.458 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2017 | 2,3,3',4,4',5,5'-Heptabromobiphenyl 88700-06-5 | C12H3Br7 706.480 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D2015 | 2,2',3,3',4,5,6'-Heptabromobiphenyl 88700-04-3 | C12H3Br7 706.480 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D2013 | 2,2',3,4',5,5',6-Heptabromobiphenyl 84303-49-1 | C12H3Br7 706.480 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D2008 | 2,2',3,3',4,5,5'-Heptabromobiphenyl 82865-92-7 | C12H3Br7 706.480 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1999 | 2,3,3',4,4',5,6-Heptabromobiphenyl 79682-25-0 | C12H3Br7 706.480 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1990 | 2,2',3,3',4,4',5-Heptabromobiphenyl 69278-60-0 | C12H3Br7 706.480 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1983 | 2,2',3,4,4',5,5'-Heptabromobiphenyl 67733-52-2 | C12H3Br7 706.480 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1949 | Heptabromobiphenyl 35194-78-6 | C12H3Br7 706.480 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1931 | 2,2',3,4',5,6,6'-Heptabromobiphenyl 119264-58-3 | C12H3Br7 706.480 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1930 | 2,2',3,4,5,6,6'-Heptabromobiphenyl 119264-57-2 | C12H3Br7 706.480 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1929 | 2,2',3,4,4',6,6'-Heptabromobiphenyl 119264-56-1 | C12H3Br7 706.480 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1928 | 2,2',3,4,4',5,6'-Heptabromobiphenyl 119264-55-0 | C12H3Br7 706.480 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1927 | 2,2',3,3',5,5',6-Heptabromobiphenyl 119264-54-9 | C12H3Br7 706.480 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D3697 | Fumonisin B2 116355-84-1 | C34H59NO14 705.831 g/mol |  |
| Fumonisins are similar in structure to the long-chain base backbones of sphingolipids, allowing it to inhibit of the biosynthesis of sphingosine and more complex sphin...more Number of Targets: 1 |
| T3D3516 | Itraconazole 84625-61-6 | C35H38Cl2N8O4 705.633 g/mol |  |
| Itraconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the f...more Number of Targets: 6 |
| T3D1587 | trans-Dichlorobis-(triphenylphosphine) palladium(II) 965-03-2 | C36H32Cl2P2Pd 703.910 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D1563 | Trihexadecylaluminum 1726-65-4 | C48H99Al 703.281 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D3035 | Posaconazole 171228-49-2 | C37H42F2N8O4 700.777 g/mol |  |
| As a triazole antifungal agent, posaconazole exerts its antifungal activity through blockage of the cytochrome P-450 dependent enzyme, sterol 14α-demethylase, in fungi...more Number of Targets: 0 |
| T3D3767 | Lolitrem B 81771-19-9 | C42H55NO7 685.889 g/mol |  |
| The neurological effects of Lolitrem B are a result of its ability to inhibit large conductance calcium-activated potassium channels (BK channels). Lolitrem B binds to...more Number of Targets: 1 |
| T3D3099 | Toxiferine 6888-23-9 | C40H46Cl2N4O2 685.725 g/mol |  |
| Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotinic acetylcholine receptors. (L1256) Number of Targets: 16 |