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Browsing Toxins By Category
Displaying toxin 351 - 375 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4569 | Cloxazolam 24166-13-0 | C17H14Cl2N2O2 349.211 g/mol |  |
| Cloxazolam is a long acting benzodiazepine. It acts as a prodrug, with pharmacologically active metabolites, which bind to to the GABAa receptor, which other benzodiaz...more Number of Targets: 18 |
| T3D4568 | Ethyl loflazepate 29177-84-2 | C18H14ClFN2O3 360.767 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 18 |
| T3D4567 | Delorazepam 2894-67-9 | C15H10Cl2N2O 305.159 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 18 |
| T3D4566 | Camazepam 36104-80-0 | C19H18ClN3O3 371.818 g/mol |  |
| Camazepam has been shown to bind competitively to benzodiazepine receptors in the brain with a relatively low affinity in animal models. This binding of benzodiazepine...more Number of Targets: 18 |
| T3D4565 | Haloxazolam 59128-97-1 | C17H14BrFN2O2 377.208 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 18 |
| T3D4564 | Clobazam 22316-47-8 | C16H13ClN2O2 300.740 g/mol |  |
| Clobazam binds at distinct binding sites associated with the chloride ionopore at the post-synaptic GABA receptor. These GABA receptors are in various locations in the...more Number of Targets: 18 |
| T3D4563 | Dexmethylphenidate 40431-64-9 | C14H19NO2 233.306 g/mol |  |
| Methylphenidate blocks dopamine uptake in central adrenergic neurons by blocking dopamine transport or carrier proteins. Methylphenidate acts at the brain stem arousal...more Number of Targets: 3 |
| T3D4562 | Heroin 561-27-3 | C21H23NO5 369.411 g/mol |  |
| Heroin is a mu-opioid agonist. It acts on endogenous mu-opioid receptors that are spread in discrete packets throughout the brain, spinal cord and gut in almost all ma...more Number of Targets: 4 |
| T3D4561 | Amobarbital 57-43-2 | C11H18N2O3 226.272 g/mol |  |
| Amobarbital (like all barbiturates) works by binding to the GABAA receptor at either the alpha or the beta sub unit. These are binding sites that are distinct from GA...more Number of Targets: 10 |
| T3D4560 | Promethazine 60-87-7 | C17H20N2S 284.419 g/mol |  |
| Like other H1-antagonists, promethazine competes with free histamine for binding at H1-receptor sites in the GI tract, uterus, large blood vessels, and bronchial muscl...more Number of Targets: 13 |
| T3D4558 | Azelastine 58581-89-8 | C22H24ClN3O 381.898 g/mol |  |
| Azelastine competes with histamine for the H1-receptor sites on effector cells and acts as an antagonist by inhibiting the release of histamine and other mediators inv...more Number of Targets: 7 |
| T3D4557 | Desloratadine 100643-71-8 | C19H19ClN2 310.821 g/mol |  |
| Like other H1-blockers, Desloratadine competes with free histamine for binding at H1-receptors in the GI tract, uterus, large blood vessels, and bronchial smooth muscl...more Number of Targets: 3 |
| T3D4556 | Guaifenesin 93-14-1 | C10H14O4 198.216 g/mol |  |
| Guaifenesin may act as an irritant to gastric vagal receptors, and recruit efferent parasympathetic reflexes that cause glandular exocytosis of a less viscous mucus mi...more Number of Targets: 0 |
| T3D4555 | Pseudoephedrine 90-82-4 | C10H15NO 165.232 g/mol |  |
| Pseudoephedrine acts directly on both alpha- and, to a lesser degree, beta-adrenergic receptors. Through direct action on alpha-adrenergic receptors in the mucosa of t...more Number of Targets: 12 |
| T3D4554 | Brompheniramine 86-22-6 | C16H19BrN2 319.239 g/mol |  |
| Brompheniramine works by acting as an antagonist of the H1 histamine receptors. It also functions as a moderately effective anticholingeric agent, likely an antimuscar...more Number of Targets: 6 |
| T3D4553 | Carbinoxamine 486-16-8 | C16H19ClN2O 290.788 g/mol |  |
| Carbinoxamine competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the n...more Number of Targets: 1 |
| T3D4552 | Eszopiclone 138729-47-2 | C17H17ClN6O3 388.808 g/mol |  |
| The mechanism of action of Eszopiclone is not completely understood. It is thought that Eszopiclone acts on the benzodiazepine receptors as an agonist and interacts wi...more Number of Targets: 8 |
| T3D4551 | Doxylamine 469-21-6 | C17H22N2O 270.369 g/mol |  |
| Like other antihistamines, doxylamine acts by competitively inhibiting histamine at H1 receptors. It also has substantial sedative and anticholinergic effects. Number of Targets: 3 |
| T3D4550 | Zoxamide 156052-68-5 | C14H16Cl3NO2 336.641 g/mol |  |
| Not Available Number of Targets: 29 |
| T3D4549 | Triticonazole 131983-72-7 | C17H20ClN3O 317.813 g/mol |  |
| Not Available Number of Targets: 16 |
| T3D4548 | Trifluralin 1582-09-8 | C13H16F3N3O4 335.279 g/mol |  |
| Not Available Number of Targets: 10 |
| T3D4547 | Triflumizole 68694-11-1 and 99387-89-0 | C15H15ClF3N3O 345.747 g/mol |  |
| Not Available Number of Targets: 35 |
| T3D4546 | Trifloxystrobin 141517-21-7 | C20H19F3N2O4 408.371 g/mol |  |
| Not Available Number of Targets: 27 |
| T3D4545 | Triclopyr 55335-06-3 | C7H4Cl3NO3 256.471 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4544 | Triadimenol 55219-65-3 | C14H18ClN3O2 295.765 g/mol |  |
| Not Available Number of Targets: 24 |