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Displaying toxins 26 - 50 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D0031Toxaphene
8001-35-2
C10H8Cl8
411.795 g/mol
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  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Toxaphene is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinester...more
Number of Targets: 52
T3D0032gamma-Hexachlorocyclohexane
58-89-9
C6H6Cl6
290.830 g/mol
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  • Antiscabies Agent
  • Drug
  • Insecticide
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Hexachlorocyclohexane is a neurotoxin that interferes with GABA neurotransmitter function by interacting with the GABA-A receptor-chloride channel complex at the picro...more
Number of Targets: 53
T3D0033Tetrachloroethylene
127-18-4
C2Cl4
165.833 g/mol
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  • Cigarette Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Organochloride
  • Pollutant
  • Solvent
  • Synthetic Compound
Tetrachloroethylene is believed to affect the central nervous system by altering the fatty acid pattern of brain phospholipids and amino acids, or being incorporated i...more
Number of Targets: 38
T3D0034Heptachlor
76-44-8
C10H5Cl7
373.318 g/mol
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  • Cigarette Toxin
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Heptachlor is a central nervous system stimulant. It non-competitively blocks neurotransmitter action at gamma-amino butyric acid receptors, resulting in overstimulati...more
Number of Targets: 40
T3D00351,2-Dibromoethane
106-93-4
C2H4Br2
187.861 g/mol
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  • Bromide Compound
  • Gasoline Additive/Component
  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Organobromide
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
The metabolite 2-bromoacetaldehyde produces liver damage by binding to cellular proteins. S-(2-bromoethyl)glutathione, another metabolite, exerts genotoxic and carcino...more
Number of Targets: 5
T3D0036beta-Hexachlorocyclohexane
319-85-7
C6H6Cl6
290.830 g/mol
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  • Metabolite
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Hexachlorocyclohexane is a neurotoxin that interferes with GABA neurotransmitter function by interacting with the GABA-A receptor-chloride channel complex at the picro...more
Number of Targets: 42
T3D0037Acrolein
107-02-8
C3H4O
56.063 g/mol
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  • Aldehyde
  • Food Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Lachrymator
  • Metabolite
  • Organic Compound
  • Pesticide
  • Pollutant
  • Synthetic Compound
Acrolein rapidly and irreversibly binds to lysine moieties and sulfhydryl groups found on many cellular molecules forming thiol ethers. By this mechanism acrolein can ...more
Number of Targets: 29
T3D0038Disulfoton
298-04-4
C8H19O2PS3
274.404 g/mol
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  • Ester
  • Ether
  • Household Toxin
  • Organic Compound
  • Organophosphate
  • Pesticide
  • Synthetic Compound
Disulfoton is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholineste...more
Number of Targets: 6
T3D0039Benzo[a]anthracene
56-55-3
C18H12
228.288 g/mol
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  • Aromatic Hydrocarbon
  • Cigarette Toxin
  • Food Toxin
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Pollutant
  • Polycyclic Aromatic Hydrocarbon
  • Synthetic Compound
The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more
Number of Targets: 7
T3D00403,3'-Dichlorobenzidine
91-94-1
C12H10Cl2N2
253.127 g/mol
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  • Amine
  • Aromatic Hydrocarbon
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
3,3’-Dichlorobenzidine's mechanism of toxicity derives mainly from the adduction of DNA by its metabolites. The formation of nitroso derivatives during metabolism, yie...more
Number of Targets: 50
T3D0041Endrin
72-20-8
C12H8Cl6O
380.909 g/mol
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  • Ether
  • Food Toxin
  • Metabolite
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Endrin antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of ch...more
Number of Targets: 42
T3D0042Beryllium
7440-41-7
Be
9.011 g/mol
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  • Beryllium Compound
  • Cigarette Toxin
  • Food Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Metal
  • Natural Compound
  • Pollutant
Once in the body, beryllium acts as a hapten and interacts with human leucocyte antigen (HLA) DP presenting cells in the lungs, becoming physically associated with a m...more
Number of Targets: 3
T3D0043delta-Hexachlorocyclohexane
319-86-8
C6H6Cl6
290.830 g/mol
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  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Hexachlorocyclohexane is a neurotoxin that interferes with GABA neurotransmitter function by interacting with the GABA-A receptor-chloride channel complex at the picro...more
Number of Targets: 42
T3D00441,2-Dibromo-3-chloropropane
96-12-8
C3H5Br2Cl
236.333 g/mol
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  • Bromide Compound
  • Organic Compound
  • Organobromide
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
The initial metabolism of 1,2-dibromo-3-chloropropane to reactive epoxide metabolites that bind to DNA and other macromolecules may be responsible for its hepatotoxici...more
Number of Targets: 54
T3D0045Pentachlorophenol
87-86-5
C6HCl5O
266.337 g/mol
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  • Aromatic Hydrocarbon
  • Industrial/Workplace Toxin
  • Lachrymator
  • Metabolite
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Pentachlorophenol is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcho...more
Number of Targets: 63
T3D0046Heptachlor epoxide
1024-57-3
C10H5Cl7O
389.317 g/mol
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  • Ether
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Heptachlor epoxide is a central nervous system stimulant. It non-competitively blocks neurotransmitter action at gamma-amino butyric acid receptors, resulting in overs...more
Number of Targets: 41
T3D0047Carbon tetrachloride
56-23-5
CCl4
153.823 g/mol
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  • Food Toxin
  • Household Toxin
  • Indicator and Reagent
  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Solvent
  • Synthetic Compound
Unmetabolized carbon tetrachloride, depresses the central nervous system. All other toxic effects of carbon tetrachloride are related to its biotransformation via cyto...more
Number of Targets: 40
T3D0048Aroclor 1221
11104-28-2
C12H9Cl
188.653 g/mol
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  • Aromatic Hydrocarbon
  • Coolant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Plasticizer
  • Pollutant
  • Polychlorinated Biphenyl
  • Synthetic Compound
The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more
Number of Targets: 7
T3D0049Cobalt
7440-48-4
Co
58.932 g/mol
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  • Cigarette Toxin
  • Cobalt Compound
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Metal
  • Natural Compound
  • Pollutant
Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more
Number of Targets: 38
T3D0050O,P'-DDT
789-02-6
C14H9Cl5
354.486 g/mol
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  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
DDT toxicity occurs via at least four mechanisms, possibly all functioning simultaneously. DDT reduces potassium transport across the membrane. DDT inhibits inactivati...more
Number of Targets: 60
T3D0051Aroclor 1016
12674-11-2
C12H7Cl3
257.543 g/mol
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  • Aromatic Hydrocarbon
  • Coolant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Plasticizer
  • Pollutant
  • Polychlorinated Biphenyl
  • Synthetic Compound
The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more
Number of Targets: 7
T3D0052Dibutyl phthalate
84-74-2
C16H22O4
278.344 g/mol
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  • Aromatic Hydrocarbon
  • Cosmetic Toxin
  • Ester
  • Ether
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Phthalate
  • Plasticizer
  • Pollutant
The most characteristic effect of di-n-butyl phthalate is testicular atrophy. Di-n-butyl phthalate exposure causes both the release of iron from hemoglobin and/or tran...more
Number of Targets: 25
T3D0053Nickel
7440-02-0
Ni
58.692 g/mol
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  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Metal
  • Natural Compound
  • Nickel Compound
  • Pollutant
Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more
Number of Targets: 73
T3D0055Endosulfan sulfate
1031-07-8
C9H6Cl6O4S
422.925 g/mol
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  • Ester
  • Food Toxin
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Endosulfan sulfate antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced ...more
Number of Targets: 42
T3D0056Diazinon
333-41-5
C12H21N2O3PS
304.346 g/mol
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  • Food Toxin
  • Household Toxin
  • Insecticide
  • Metabolite
  • Organic Compound
  • Organophosphate
  • Pesticide
  • Synthetic Compound
Diazinon is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more
Number of Targets: 12
Displaying toxins 26 - 50 of 3678 in total