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Displaying toxin 676 - 700 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D0794Actinolite Asbestos
77536-66-4
(Na, K)0-1Ca2(Mg, Fe)5Si8O22(OH)2
Not Available
T3d0794
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Mineral
  • Natural Compound
  • Pollutant
When asbestos fibers are inhaled, many are deposited on the epithelial surface of the respiratory tree. Fibers that are retained in the lung or mesothelium for long pe...more
Number of Targets: 1
T3D0795Anthophyllite Asbestos
77536-67-5
(Na, K)0-1Mg2(Mg, Fe)5Si8O22(OH)2, Mg/(Mg + Fe) > 0.6
Not Available
T3d0795
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Mineral
  • Natural Compound
  • Pollutant
When asbestos fibers are inhaled, many are deposited on the epithelial surface of the respiratory tree. Fibers that are retained in the lung or mesothelium for long pe...more
Number of Targets: 1
T3D0796Tin
7440-31-5
Sn
118.710 g/mol
Thumb
  • Food Toxin
  • Household Toxin
  • Inorganic Compound
  • Metabolite
  • Metal
  • Natural Compound
  • Pesticide
  • Tin Compound
Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more
Number of Targets: 15
T3D0797Imidacloprid
105827-78-9
C9H10ClN5O2
255.661 g/mol
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  • Amide
  • Amine
  • Aromatic Hydrocarbon
  • Food Toxin
  • Household Toxin
  • Insecticide
  • Metabolite
  • Neonicotinoid
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Imidacloprid acts on the nicotinic acetylcholine receptor; the chlorination inhibits degradation by acetylcholine-esterase (L1130).
Number of Targets: 12
T3D0798Fipronil
120068-37-3
C12H4Cl2F6N4OS
437.148 g/mol
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  • Amine
  • Aromatic Hydrocarbon
  • Household Toxin
  • Nitrile
  • Organic Compound
  • Organochloride
  • Organofluoride
  • Pesticide
  • Synthetic Compound
Fipronil blocks the passage of chloride ions through the GABA-regulated chloride channel, disrupting CNS activity. (T10) Organic nitriles decompose into cyanide ions b...more
Number of Targets: 29
T3D0799Nicotine
54-11-5
C10H14N2
162.232 g/mol
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  • Amine
  • Anti-Craving Agent
  • Appetite Depressant
  • Autonomic Agent
  • Central Nervous System Agent
  • Drug
  • Food Toxin
  • Ganglionic Stimulant
  • Household Toxin
  • Insecticide
  • Metabolite
  • Natural Compound
  • Nicotinic Agonist
  • Organic Compound
  • Pesticide
Nicotine is a stimulant drug that acts as an agonist at nicotinic acetylcholine receptors. These are ionotropic receptors composed up of five homomeric or heteromeric ...more
Number of Targets: 22
T3D0800Rotenone
83-79-4
C20H18O6
354.353 g/mol
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  • Aromatic Hydrocarbon
  • Ester
  • Ether
  • Food Toxin
  • Household Toxin
  • Lachrymator
  • Metabolite
  • Organic Compound
  • Pesticide
  • Synthetic Compound
Rotenone works by interfering with the electron transport chain in mitochondria. Specifically, it inhibits the transfer of electrons from iron-sulfur centers in comple...more
Number of Targets: 47
T3D0801Dichlorprop
120-36-5
C9H8Cl2O3
235.064 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Ether
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more
Number of Targets: 6
T3D08022,4-Dichlorophenoxybutyric acid
94-82-6
C10H10Cl2O3
249.091 g/mol
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  • Aromatic Hydrocarbon
  • Ether
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Some of the endocrine effects of 2,4-DB may be mediated by the 2,4-D mediated displacement of sex hormones from the sex hormone binding globulin or the 2,4-D mediated ...more
Number of Targets: 9
T3D08032,4,5-Trichlorophenoxyacetic acid
93-76-5
C8H5Cl3O3
255.483 g/mol
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  • Aromatic Hydrocarbon
  • Ether
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more
Number of Targets: 3
T3D08042-Methyl-4-chlorophenoxyacetic acid
94-74-6
C9H9ClO3
200.619 g/mol
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  • Aromatic Hydrocarbon
  • Ether
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more
Number of Targets: 6
T3D08054-(4-Chloro-2-methylphenoxy)butanoic acid
94-81-5
C11H13ClO3
228.672 g/mol
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  • Aromatic Hydrocarbon
  • Ether
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Not Available
Number of Targets: 3
T3D0806Methylchlorophenoxypropionic acid
93-65-2
C10H11ClO3
214.646 g/mol
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  • Aromatic Hydrocarbon
  • Ether
  • Household Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more
Number of Targets: 3
T3D0807Dicamba
1918-00-9
C8H6Cl2O3
221.037 g/mol
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  • Amine
  • Aromatic Hydrocarbon
  • Herbicide
  • Household Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Not Available
Number of Targets: 5
T3D0808Paraquat dichloride
1910-42-5
C12H14Cl2N2
257.159 g/mol
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  • Aromatic Hydrocarbon
  • Food Toxin
  • Herbicide
  • Lachrymator
  • Metabolite
  • Organic Compound
  • Pesticide
  • Synthetic Compound
The mechanisms of the toxic effects of paraquat are largely the result of a metabolically catalyzed single electron oxidation reduction reaction, resulting in depletio...more
Number of Targets: 4
T3D0810Alachlor
15972-60-8
C14H20ClNO2
269.767 g/mol
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  • Amide
  • Amine
  • Aromatic Hydrocarbon
  • Chloroacetanilide
  • Ether
  • Food Toxin
  • Herbicide
  • Household Toxin
  • Metabolite
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Its mode of action is elongase inhibition, and inhibition of geranylgeranyl pyrophosphate (GGPP) cyclisation enzymes. It is also know to inhibit biosynthesis of fatty...more
Number of Targets: 26
T3D0811Acetochlor
34256-82-1
C14H20ClNO2
269.767 g/mol
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  • Amide
  • Amine
  • Aromatic Hydrocarbon
  • Chloroacetanilide
  • Ether
  • Herbicide
  • Household Toxin
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Its mode of action is elongase inhibition, and inhibition of geranylgeranyl pyrophosphate (GGPP) cyclisation enzymes (L920).
Number of Targets: 23
T3D0812Glufosinate
51276-47-2
C5H12NO4P
181.127 g/mol
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  • Amine
  • Herbicide
  • Organic Compound
  • Pesticide
  • Synthetic Compound
Glufosinate irreversibly inhibits the enzyme glutamine synthetase, which decreases ammonia detoxification. Increased ammonia levels lead to impairment of photorespirat...more
Number of Targets: 1
T3D0813Amygdalin
29883-15-6
C20H27NO11
457.429 g/mol
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  • Cyanide Compound
  • Cyanogenic Glycoside
  • Ether
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Nitrile
  • Organic Compound
  • Plant Toxin
Amygdalin can be metabolized into hydrogen cyanide in the stomach causing discomfort or illness. (L402) Organic nitriles decompose into cyanide ions both in vivo and i...more
Number of Targets: 0
T3D0815Angelicin
523-50-2
C11H6O3
186.164 g/mol
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  • Aromatic Hydrocarbon
  • Ester
  • Food Toxin
  • Furocoumarin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
The mechanism of action many furocoumarins is based on their ability to form photoadducts with DNA and other cellular components such as RNA, proteins, and several pro...more
Number of Targets: 4
T3D0816Isobergapten
482-48-4
C12H8O4
216.190 g/mol
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  • Aromatic Hydrocarbon
  • Ester
  • Ether
  • Food Toxin
  • Furocoumarin
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Inhibits insect cytochrome P450 (L579). The mechanism of action many furocoumarins is based on their ability to form photoadducts with DNA and other cellular component...more
Number of Targets: 3
T3D0819Sphondin
483-66-9
C12H8O4
216.190 g/mol
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  • Aromatic Hydrocarbon
  • Ester
  • Ether
  • Food Toxin
  • Furocoumarin
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Sphondin possesses an inhibitory effect on IL-1b-induced COX-2 protein expression and PGE2 release in human pulmonary epithelial cell line (A549). The mechanism of act...more
Number of Targets: 3
T3D0821Heratomin
61265-06-3
C16H14O4
270.280 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Ester
  • Ether
  • Food Toxin
  • Furocoumarin
  • Natural Compound
  • Organic Compound
  • Plant Toxin
The mechanism of action many furocoumarins is based on their ability to form photoadducts with DNA and other cellular components such as RNA, proteins, and several pro...more
Number of Targets: 3
T3D0822Pimpinellin
131-12-4
C13H10O5
246.216 g/mol
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  • Aromatic Hydrocarbon
  • Ester
  • Ether
  • Food Toxin
  • Furocoumarin
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Pimpinellin acts as antagonist of proteins with GABA receptor activity (L579). The mechanism of action many furocoumarins is based on their ability to form photoadduct...more
Number of Targets: 3
T3D0825Psoralen
66-97-7
C11H6O3
186.164 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Ester
  • Food Toxin
  • Furocoumarin
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
The mechanism of action many furocoumarins is based on their ability to form photoadducts with DNA and other cellular components such as RNA, proteins, and several pro...more
Number of Targets: 4
Displaying toxin 676 - 700 of 3678 in total