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Displaying toxins 76 - 100 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D00872,4-Dinitrophenol
51-28-5
C6H4N2O5
184.106 g/mol
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  • Aromatic Hydrocarbon
  • Food Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Nitrite
  • Organic Compound
  • Pesticide
  • Pollutant
  • Synthetic Compound
Acute 2,4-dinitrophenol poisoning (from ingestion) involves uncoupling of oxidative phosphorylation, which presumably reduces body's reservoirs of high-energy phosphat...more
Number of Targets: 1
T3D0088Bis(2-chloroethyl) ether
111-44-4
C4H8Cl2O
143.012 g/mol
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  • Ether
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
BCEE is extremely meabolized, with thiodiglycolic acid (TDGA) being the principal endproduct. The pathway leading to TDGA formation is uncertain, but probably involves...more
Number of Targets: 38
T3D0089Thiocyanate
302-04-5
CNS
58.083 g/mol
Thumb
  • Cyanide Compound
  • Food Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Nitrile
  • Organic Compound
  • Plant Toxin
  • Pollutant
Thiocyanate (sulphocyanate or SCN) is believed to be a goitrogenic compound. It is a competitive inhibitor of the human thyroid sodium/iodide symporter NIS. Thus, the ...more
Number of Targets: 8
T3D0091Chloride ion
22537-115-1
Cl
35.454 g/mol
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  • Halogen
  • Inorganic Compound
  • Natural Compound
Chloride imbalances can lead to electrolyte and pH imbalances. Excessive chloride in the blood is known as hyperchloremia. Often hyperchloremia is associated with ex...more
Number of Targets: 16
T3D0092Cyclotrimethylenetrinitramine
121-82-4
C3H6N6O6
222.116 g/mol
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  • Amine
  • Explosive Agent
  • Industrial/Workplace Toxin
  • Nitrite
  • Organic Compound
  • Synthetic Compound
RDX can get into the lungs after breathing in the fumes of burning RDX or breathing in the dust from powdered RDX. It can also enter the body after ingestion of contam...more
Number of Targets: 0
T3D0093Hexachlorobenzene
118-74-1
C6Cl6
284.782 g/mol
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  • Aromatic Hydrocarbon
  • Food Toxin
  • Metabolite
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Hexachlorobenzene causes porphyria by modifying sulfhydryl groups in the catalytic or substrate-binding sites of uroporphyrinogen decarboxylase. This inhibits uroporph...more
Number of Targets: 43
T3D00942,4-Dinitrotoluene
121-14-2
C7H6N2O4
182.134 g/mol
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  • Aromatic Hydrocarbon
  • Explosive Agent
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Nitrite
  • Organic Compound
  • Plasticizer
  • Pollutant
  • Synthetic Compound
2,4-DNT may cause conversion of oxyhemoglobin to methemoglobin via oxidation of iron(II) to iron(III) by its metabolites. High levels of methemoglobin are removed by c...more
Number of Targets: 11
T3D0096Ethion
563-12-2
C9H22O4P2S4
384.476 g/mol
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  • Ester
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organophosphate
  • Pesticide
  • Synthetic Compound
Ethion is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinesterase...more
Number of Targets: 10
T3D00971,1,1-Trichloroethane
71-55-6
C2H3Cl3
133.404 g/mol
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  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Organochloride
  • Pollutant
  • Solvent
  • Synthetic Compound
1,1,1-Trichloroethane is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acety...more
Number of Targets: 41
T3D0099Ethylbenzene
100-41-4
C8H10
106.165 g/mol
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  • Aromatic Hydrocarbon
  • Cigarette Toxin
  • Food Toxin
  • Household Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Pollutant
  • Synthetic Compound
Changes in the integrity of the cell membrane after partitioning of ethylbenzene into the lipid bilayer may subsequently affect the function of membrane, particularly ...more
Number of Targets: 17
T3D0100Radium-226
13982-63-3
Ra
226.025 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Natural Compound
  • Pollutant
  • Radioactive
  • Radioactive Isotope
  • Radium Compound
Ionizing radiation produced by radium damages the DNA, resulting in gene mutations and chromosomal aberrations. This can both initiate and promote carcinogenesis, and ...more
Number of Targets: 1
T3D0101Thorium
7440-29-1
Th
232.038 g/mol
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  • Food Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Metal
  • Natural Compound
  • Pollutant
  • Radioactive
  • Radioactive Isotope
  • Thorium Compound
The ionizing radiation produced by thorium causes cellular damage that includes DNA breakage, accurate or inaccurate repair, apoptosis, gene mutations, chromosomal cha...more
Number of Targets: 1
T3D01024,6-Dinitro-o-cresol
534-52-1
C7H6N2O5
198.133 g/mol
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  • Aromatic Hydrocarbon
  • Nitrite
  • Organic Compound
  • Pesticide
  • Pollutant
  • Synthetic Compound
4,6-Dinitro-o-cresol is an uncoupler of oxidative phosphorylation. It is believed to cause an acceleration of metabolic processes that are part of the tricarboxylic ac...more
Number of Targets: 4
T3D01031,3,5-Trinitrobenzene
99-35-4
C6H3N3O6
213.105 g/mol
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  • Aromatic Hydrocarbon
  • Explosive Agent
  • Industrial/Workplace Toxin
  • Nitrite
  • Organic Compound
  • Synthetic Compound
In the red blood cell, 1,3,5-TNB induces formation of methemoglobin, leading to cyanosis. Reduction of the nitrogroup(s) of 1,3,5-TNB produces reactive nitroaromatic r...more
Number of Targets: 0
T3D0104Chlorobenzene
108-90-7
C6H5Cl
112.557 g/mol
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  • Aromatic Hydrocarbon
  • Household Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Solvent
  • Synthetic Compound
The reactive metabolites of chlorobenzene are believed to bind both liver and kidney proteins, causing direct damage. Chlorobenzene also activates nuclear factor-kappa...more
Number of Targets: 38
T3D0105Radon
10043-92-2
Rn
222.000 g/mol
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  • Cigarette Toxin
  • Inorganic Compound
  • Natural Compound
  • Nobel Gas
  • Non-Metal
  • Pollutant
  • Radioactive
  • Radioactive Isotope
The ionizing radiation produced by radon causes cellular damage that includes DNA breakage, accurate or inaccurate repair, apoptosis, gene mutations, chromosomal chang...more
Number of Targets: 1
T3D0106Radium-228
15262-20-1
Ra
228.031 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Natural Compound
  • Pollutant
  • Radioactive
  • Radioactive Isotope
  • Radium Compound
Ionizing radiation produced by radium damages the DNA, resulting in gene mutations and chromosomal aberrations. This can both initiate and promote carcinogenesis, and ...more
Number of Targets: 1
T3D0107Thorium-230
14269-63-7
Th
230.033 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Natural Compound
  • Pollutant
  • Radioactive
  • Radioactive Isotope
  • Thorium Compound
The ionizing radiation produced by thorium causes cellular damage that includes DNA breakage, accurate or inaccurate repair, apoptosis, gene mutations, chromosomal cha...more
Number of Targets: 1
T3D0108Uranium-235
15117-96-1
U
235.044 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Natural Compound
  • Pollutant
  • Radioactive
  • Radioactive Isotope
  • Uranium Compound
Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and prot...more
Number of Targets: 1
T3D0109Barium
7440-39-3
Ba
137.326 g/mol
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  • Barium Compound
  • Food Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Metal
  • Natural Compound
Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to...more
Number of Targets: 22
T3D0110Fluoranthene
206-44-0
C16H10
202.251 g/mol
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  • Aromatic Hydrocarbon
  • Food Toxin
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Natural Compound
  • Organic Compound
  • Pollutant
  • Polycyclic Aromatic Hydrocarbon
The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more
Number of Targets: 6
T3D0111Uranium-234
13966-29-5
U
234.041 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Natural Compound
  • Pollutant
  • Radioactive
  • Radioactive Isotope
  • Uranium Compound
Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and prot...more
Number of Targets: 1
T3D0112n-Nitrosodi-n-propylamine
621-64-7
C6H14N2O
130.188 g/mol
Thumb
  • Amine
  • Cigarette Toxin
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Nitrite
  • Organic Compound
  • Pollutant
  • Synthetic Compound
Reactive metabolites of n-nitrosodi-n-propylamine are believed to form adducts with DNA, resulting in carcinogenic effects. (L216)
Number of Targets: 1
T3D0113Thorium-228
14274-82-9
Th
228.029 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Natural Compound
  • Pollutant
  • Radioactive
  • Radioactive Isotope
  • Thorium Compound
The ionizing radiation produced by thorium causes cellular damage that includes DNA breakage, accurate or inaccurate repair, apoptosis, gene mutations, chromosomal cha...more
Number of Targets: 1
T3D0114Radon-222
14859-67-7
Rn
222.018 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Natural Compound
  • Non-Metal
  • Pollutant
  • Radioactive
  • Radioactive Isotope
  • Radium Compound
The ionizing radiation produced by radon causes cellular damage that includes DNA breakage, accurate or inaccurate repair, apoptosis, gene mutations, chromosomal chang...more
Number of Targets: 1
Displaying toxins 76 - 100 of 3678 in total