Record Information
Version2.0 (beta)
Creation Date2009-03-06 11:58:06 -0700
Update Date2014-08-30 00:54:12 -0600
Accession NumberT3D0116
Identification
Common Name1,2,3-Trichlorobenzene
ClassSmall Molecule
Description1,2,3-Trichlorobenzene is an organochloride aromatic compound and one of the three isomeric forms of trichlorobenzene. Trichlorobenzene is used as a solvent. (7)
Compound Type
  • Organic Compound
  • Organochloride
  • Aromatic Hydrocarbon
  • Solvent
Chemical Structure
Thumb
Synonyms
  1. 1,2, 3-Trichlorobenzene
  2. 1,2,3-Trichlorbenzol
  3. 1,2,3-Trichlorobenzene
  4. 1,2,6-Trichlorobenzene
  5. Trichlorbenzene
  6. Trichlorobencenos [spanish]
  7. Trichlorobenzene
  8. Trichlorobenzenes
  9. Vic-trichlorobenzene
Chemical FormulaC6H3Cl3
Average Molecular Weight181.447 g/mol
CAS Registry Number87-61-6
Monoisotopic Mass179.930033217 g/mol
IUPAC Name1,2,3-trichlorobenzene
Traditional IUPAC Name1,2,3-trichlorobenzene
SMILESClC1=CC=CC(Cl)=C1Cl
InChI IdentifierInChI=1S/C6H3Cl3/c7-4-2-1-3-5(8)6(4)9/h1-3H
InChI KeyInChIKey=RELMFMZEBKVZJC-UHFFFAOYSA-N
Chemical Taxonomy
KingdomOrganic Compounds
Super ClassBenzenoids
ClassBenzene and Substituted Derivatives
Sub ClassHalobenzenes
Direct ParentChlorobenzenes
Alternative Parents
  • Aryl Chlorides
  • Heterocyclic Compounds
  • Organochlorides
Substituents
  • chlorobenzene
  • aryl chloride
  • organochloride
  • Heterocycle
  • Aromatic Homomonocyclic Compound
  • Aryl Halide
  • Organohalogen Compound
External DescriptorsNot Available
Biological Properties
StatusDetected but not Quantified
OriginNot Available
Cellular Locations
  • Membrane Fraction
Biofluid LocationsNot Available
Tissue LocationsNot Available
PathwaysNot Available
Physical Properties
StateNot Available
AppearanceWhite crystals.
Experimental Properties
PropertyValue
Melting Point53.5 C
Boiling PointNot Available
Solubility0.018 mg/mL at 25 °C [CHIOU,CT et al. (1986)]
LogPNot Available
Predicted Properties
PropertyValueSource
water solubility3.10e-02 g/lALOGPS
logP4.07ALOGPS
logP3.79ChemAxon
logS-3.8ALOGPS
physiological charge0ChemAxon
hydrogen acceptor count0ChemAxon
hydrogen donor count0ChemAxon
polar surface area0ChemAxon
rotatable bond count0ChemAxon
refractivity40.47ChemAxon
polarizability15.27ChemAxon
Spectra
SpectraNot Available
Toxicity Profile
Route of ExposureOral (5) ; inhalation (5) ; dermal (5)
Mechanism of ToxicityTrichlorobenzene may uncouple mitochondrial oxidative phosphorylation, inducing potassium ion release and inhibiting respiratory control. It's metabolites may covalently bind to cellular proteins and alkylate DNA. (2, 3)
MetabolismTrichlorobenzene is absorbed via oral, inhalation, and dermal routes. It is believed to be metabolized via cytochrome p-450 enzymes into metabolites that include phenols, mercapturic acid, and catechols.(5)
Toxicity ValuesLD50: 756 mg/kg (Oral, Rat) (4)
Lethal DoseNot Available
Carcinogenicity (IARC Classification)Not Available
Uses/SourcesTrichlorobenzene is used as a solvent in chemical manufacturing, as well as in dyes, dielectric fluid, synthetic transformer oils, lubricants, heat-transfer medium, and insecticides. (6)
Minimum Risk LevelNot Available
Health EffectsHigh levels of trichlorobenzene may damage the liver, kidney, and thyroid. (1)
SymptomsTrichlorobenzene irritates the eyes and respiratory tract. (4)
TreatmentNot Available
Concentrations
Not Available
DrugBank IDNot Available
HMDB IDNot Available
PubChem Compound ID6895
ChEMBL IDCHEMBL46557
ChemSpider ID13864445
KEGG IDC14408
UniProt IDNot Available
OMIM IDNot Available
ChEBI ID35289
BioCyc IDCPD-1125
CTD IDNot Available
Stitch ID1,2,3-Trichlorobenzene
PDB IDNot Available
ACToR ID3345
Wikipedia LinkNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General References
  1. Cote M, Chu I, Villeneuve DC, Secours VE, Valli VE: Trichlorobenzenes: results of a thirteen week feeding study in the rat. Drug Chem Toxicol. 1988;11(1):11-28. [3378508 ]
  2. Ogata M, Hasegawa T, Mori T, Meguro T: Effects of chlorinated mono aromatic hydrocarbons on mitochondrial oxidative phosphorylation in rats liver. Ind Health. 1981;19(1):31-6. [7216839 ]
  3. den Besten C, Smink MC, de Vries EJ, van Bladeren PJ: Metabolic activation of 1,2,4-trichlorobenzene and pentachlorobenzene by rat liver microsomes: a major role for quinone metabolites. Toxicol Appl Pharmacol. 1991 Apr;108(2):223-33. [2017752 ]
  4. American Conference of Governmental Industrial Hygienists, Inc. (1991). Documentation of the Threshold Limit Values and Biological Exposure Indices. 6th ed. Volumes I, II, III. Cincinnati, OH: American Conference of Governmental Industrial Hygienists.
  5. USEPA (1980). Ambient Water Quality Criteria Doc: Chlorinated Benzenes. EPA 440/5-80-028.
  6. Lewis RJ Sr. (ed) (1993). Hawley's Condensed Chemical Dictionary. 12th ed. New York, NY: Van Nostrand Rheinhold Co.
  7. Wikipedia. Trichlorobenzene. Last Updated 30 August 2007. [Link]
Gene Regulation
Up-Regulated GenesNot Available
Down-Regulated GenesNot Available

Targets

General function:
Involved in transcription factor activity
Specific function:
Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues
Gene Name:
ESR1
Uniprot ID:
P03372
Molecular weight:
66217.0

Constants

TypeValueAssay TypeAssay Source
AC502.37 uMACEA_T47D_80hr_PositiveACEA Biosciences
References
  1. Taccone-Gallucci M, Manca-di-Villahermosa S, Battistini L, Stuffler RG, Tedesco M, Maccarrone M: N-3 PUFAs reduce oxidative stress in ESRD patients on maintenance HD by inhibiting 5-lipoxygenase activity. Kidney Int. 2006 Apr;69(8):1450-4. [16531984 ]
  2. Luft S, Milki E, Glustrom E, Ampiah-Bonney R, O'Hara P. Binding of Organochloride and Pyrethroid Pesticides To Estrogen Receptors α and β: A Fluorescence Polarization Assay. Biophysical Journal 2009;96(3):444a.
  3. ToxCastDB (EPA, United States Environmental Protection Agency) [Link]
General function:
Involved in transcription factor activity
Specific function:
Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA- binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual
Gene Name:
ESR2
Uniprot ID:
Q92731
Molecular weight:
59217.0
References
  1. Taccone-Gallucci M, Manca-di-Villahermosa S, Battistini L, Stuffler RG, Tedesco M, Maccarrone M: N-3 PUFAs reduce oxidative stress in ESRD patients on maintenance HD by inhibiting 5-lipoxygenase activity. Kidney Int. 2006 Apr;69(8):1450-4. [16531984 ]
  2. Luft S, Milki E, Glustrom E, Ampiah-Bonney R, O'Hara P. Binding of Organochloride and Pyrethroid Pesticides To Estrogen Receptors α and β: A Fluorescence Polarization Assay. Biophysical Journal 2009;96(3):444a.
General function:
Inorganic ion transport and metabolism
Specific function:
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium
Gene Name:
ATP2C1
Uniprot ID:
P98194
Molecular weight:
100579.0
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Not Available
Specific function:
Not Available
Gene Name:
Not Available
Uniprot ID:
O75185
Molecular weight:
Not Available
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Involved in GABA-A receptor activity
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
Gene Name:
GABRA1
Uniprot ID:
P14867
Molecular weight:
51802.0
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Involved in GABA-A receptor activity
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
Gene Name:
GABRA2
Uniprot ID:
P47869
Molecular weight:
51340.0
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Involved in GABA-A receptor activity
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
Gene Name:
GABRA3
Uniprot ID:
P34903
Molecular weight:
55165.0
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Involved in GABA-A receptor activity
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
Gene Name:
GABRA4
Uniprot ID:
P48169
Molecular weight:
61641.0
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Involved in GABA-A receptor activity
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
Gene Name:
GABRA5
Uniprot ID:
P31644
Molecular weight:
52147.0
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Involved in GABA-A receptor activity
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
Gene Name:
GABRA6
Uniprot ID:
Q16445
Molecular weight:
51035.0
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Not Available
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
Gene Name:
GABRB1
Uniprot ID:
P18505
Molecular weight:
54235.0
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Not Available
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
Gene Name:
GABRB2
Uniprot ID:
P47870
Molecular weight:
54607.0
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Not Available
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
Gene Name:
GABRB3
Uniprot ID:
P28472
Molecular weight:
54116.0
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Involved in chloride channel activity
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
Gene Name:
GABRD
Uniprot ID:
O14764
Molecular weight:
50707.8
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Involved in chloride channel activity
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
Gene Name:
GABRE
Uniprot ID:
P78334
Molecular weight:
57971.2
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Involved in chloride channel activity
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
Gene Name:
GABRG1
Uniprot ID:
Q8N1C3
Molecular weight:
53594.5
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Involved in benzodiazepine receptor activity
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
Gene Name:
GABRG2
Uniprot ID:
P18507
Molecular weight:
54161.8
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Involved in chloride channel activity
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
Gene Name:
GABRG3
Uniprot ID:
Q99928
Molecular weight:
54288.2
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Involved in chloride channel activity
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. In the uterus, the function of the receptor appears to be related to tissue contractility. The binding of this pI subunit with other GABA(A) receptor subunits alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone
Gene Name:
GABRP
Uniprot ID:
O00591
Molecular weight:
50639.7
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Involved in GABA-A receptor activity
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission
Gene Name:
GABRR1
Uniprot ID:
P24046
Molecular weight:
55258.0
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Involved in chloride channel activity
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-2 GABA receptor could play a role in retinal neurotransmission
Gene Name:
GABRR2
Uniprot ID:
P28476
Molecular weight:
54150.4
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Involved in chloride channel activity
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel (By similarity)
Gene Name:
GABRR3
Uniprot ID:
A8MPY1
Molecular weight:
54271.1
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Involved in chloride channel activity
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
Gene Name:
GABRQ
Uniprot ID:
Q9UN88
Molecular weight:
72020.9
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Not Available
Specific function:
Not Available
Gene Name:
Not Available
Uniprot ID:
P20020
Molecular weight:
Not Available
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Not Available
Specific function:
Not Available
Gene Name:
Not Available
Uniprot ID:
Q01814
Molecular weight:
Not Available
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Not Available
Specific function:
Not Available
Gene Name:
Not Available
Uniprot ID:
Q16720
Molecular weight:
Not Available
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Not Available
Specific function:
Not Available
Gene Name:
Not Available
Uniprot ID:
P23634
Molecular weight:
Not Available
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Inorganic ion transport and metabolism
Specific function:
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction
Gene Name:
ATP2A1
Uniprot ID:
O14983
Molecular weight:
110251.4
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Inorganic ion transport and metabolism
Specific function:
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Isoform SERCA2A is involved in the regulation of the contraction/relaxation cycle
Gene Name:
ATP2A2
Uniprot ID:
P16615
Molecular weight:
114755.8
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Not Available
Specific function:
Not Available
Gene Name:
Not Available
Uniprot ID:
Q93084
Molecular weight:
Not Available
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Inorganic ion transport and metabolism
Specific function:
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients
Gene Name:
ATP1A1
Uniprot ID:
P05023
Molecular weight:
112897.0
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Not Available
Specific function:
Not Available
Gene Name:
Not Available
Uniprot ID:
P50993
Molecular weight:
Not Available
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Not Available
Specific function:
Not Available
Gene Name:
Not Available
Uniprot ID:
P13637
Molecular weight:
Not Available
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Not Available
Specific function:
Not Available
Gene Name:
Not Available
Uniprot ID:
Q13733
Molecular weight:
Not Available
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Not Available
Specific function:
Not Available
Gene Name:
Not Available
Uniprot ID:
P05026
Molecular weight:
Not Available
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Not Available
Specific function:
Not Available
Gene Name:
Not Available
Uniprot ID:
P14415
Molecular weight:
Not Available
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Not Available
Specific function:
Not Available
Gene Name:
Not Available
Uniprot ID:
P54709
Molecular weight:
Not Available
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Involved in ion channel activity
Specific function:
May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase
Gene Name:
FXYD2
Uniprot ID:
P54710
Molecular weight:
7283.0
References
  1. Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
General function:
Not Available
Specific function:
Not Available
Gene Name:
Not Available
Uniprot ID:
P22932
Molecular weight:
Not Available

Constants

TypeValueAssay TypeAssay Source
AC501.02 uMATG_RARg_TRANSAttagene
References
  1. ToxCastDB (EPA, United States Environmental Protection Agency) [Link]
General function:
Not Available
Specific function:
Not Available
Gene Name:
Not Available
Uniprot ID:
P60484
Molecular weight:
Not Available

Constants

TypeValueAssay TypeAssay Source
AC501.06 uMNVS_ENZ_hPTENNovascreen
References
  1. ToxCastDB (EPA, United States Environmental Protection Agency) [Link]
General function:
Involved in tissue proteolysis activity
Specific function:
In addition to gelatin and collagens, it cleaves KiSS1 at a Gly-|-Leu bond
Gene Name:
MMP2
Uniprot ID:
P08253
Molecular weight:
73883.0

Constants

TypeValueAssay TypeAssay Source
AC507.70 uMNVS_ENZ_hMMP2Novascreen
References
  1. ToxCastDB (EPA, United States Environmental Protection Agency) [Link]