734
T3D0733
Zinc iodide
Zinc iodide is a iodide of zinc. It is used in x-rays and electron microscopy. Zinc is a metallic element with the atomic number 30. It is found in nature most often as the mineral sphalerite. Though excess zinc in harmful, in smaller amounts it is an essential element for life, as it is a cofactor for over 300 enzymes and is found in just as many transcription factors. (L48, L49, L69)
10139-47-6
66278
I2Zn
317.738080
White crystals.
446°C
1150°C decomposes
Inhalation (L49) ; oral (L49) ; dermal (L49)
Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unbalanced levels of copper and zinc binding to Cu,Zn-superoxide dismutase has been linked to amyotrophic lateral sclerosis (ALS). Stomach acid dissolves metallic zinc to give corrosive zinc chloride, which can cause damage to the stomach lining. Metal fume fever is thought to be an immune response to inhaled zinc. (L48, L49, A49)
Zinc can enter the body through the lungs, skin, and gastrointestinal tract. Intestinal absorption of zinc is controlled by zinc carrier protein CRIP. Zinc also binds to metallothioneins, which help prevent absorption of excess zinc. Zinc is widely distributed and found in all tissues and tissues fluids, concentrating in the liver, gastrointestinal tract, kidney, skin, lung, brain, heart, and pancreas. In the bloodstream zinc is found bound to carbonic anhydrase in erythrocytes, as well as bound to albumin, _2-macroglobulin, and amino acids in the the plasma. Albumin and amino acid bound zinc can diffuse across tissue membranes. Zinc is excreted in the urine and faeces. (L49)
No indication of carcinogenicity to humans (not listed by IARC).
Zinc iodide is used in x-rays and electron microscopy. (L69)
Intermediate Oral: 0.3 mg/kg/day (L134)
Chronic Oral: 0.3 mg/kg/day (L134)
Chronic exposure to zinc causes anemia, atazia, lethargy, and decreases the level of good cholesterol in the body. It is also believed to cause pancreatic and reproductive damage. (L49)
Ingestion of large doses of zinc causes stomach cramps, nausea, and vomiting. Acute inhalation of large amounts of zinc causes metal fume fever, which is characterized by chills, fever, headache, weakness, dryness of the nose and throat, chest pain, and coughing. Dermal contact with zinc results in skin irritation. (L49)
Zinc poisoning is treated symptomatically, often by administering fluids such as water or milk, or with gastric lavage. (L49)
2009-03-27T01:02:18Z
2014-12-24T20:22:42Z
Metallothionein-2 (P02795)
Metallothionein-1G (P13640)
Metallothionein-1H (P80294)
Metallothionein-3 (P25713)
Metallothionein-1F (P04733)
Metallothionein-1E (P04732)
Metallothionein-1X (P80297)
Metallothionein-1A (P04731)
Metallothionein-1B (P07438)
Metallothionein-1M (Q8N339)
Metallothionein-4 (P47944)
Metallothionein-1L (Q93083)
Cysteine-rich protein 1 (P50238)
Cysteine-rich protein 2 (P52943)
Cysteine-rich protein 3 (Q6Q6R5)
Serum albumin (P02768)
(L49, A49, L92)
C029770
Zinc iodide
true
Metallothionein-2 (P02795)
Metallothionein-1G (P13640)
Metallothionein-1H (P80294)
Metallothionein-3 (P25713)
Metallothionein-1F (P04733)
Metallothionein-1E (P04732)
Metallothionein-1X (P80297)
Metallothionein-1A (P04731)
Metallothionein-1B (P07438)
Metallothionein-1M (Q8N339)
Metallothionein-4 (P47944)
Metallothionein-1L (Q93083)
Cysteine-rich protein 1 (P50238)
Cysteine-rich protein 2 (P52943)
Cysteine-rich protein 3 (Q6Q6R5)
Serum albumin (P02768)
(L49, A49, L92)
I[Zn]I
I2Zn
InChI=1S/2HI.Zn/h2*1H;/q;;+2/p-2
InChIKey=UAYWVJHJZHQCIE-UHFFFAOYSA-L
319.218
317.738083418
Exogenous
Solid
59657