2686
T3D2645
Brevetoxin
Brevetoxins are cyclic polyether compounds produced naturally by a species of dinoflagellates (Karenia brevis). They are neurotoxins that bind to voltage-gated sodium channels in nerve cells, leading to disruption of normal neurological processes and causing the illness clinically described as neurotoxic shellfish poisoning. (L1112)
98112-41-5
105135
C49H68O14
867.0723
White powder.
Injection (sting/bite) (L1815)
Brevetoxins are neurotoxins that bind to voltage-gated sodium channels in nerve cells, leading to disruption of normal neurological processes. (L1112)
No indication of carcinogenicity to humans (not listed by IARC).
Brevetoxins are cyclic polyether compounds produced naturally by a species of dinoflagellates (Karenia brevis). (L1112)
Brevetoxins are neurotoxins that cause the illness clinically described as neurotoxic shellfish poisoning. (L1112)
Brevetoxins are neurotoxins that cause the illness clinically described as neurotoxic shellfish poisoning. Symptoms include vomiting and nausea and a variety of neurologic symptoms such as slurred speech. (L1112)
2009-07-06T21:35:50Z
2014-12-24T20:25:48Z
C16839
Brevetoxin
true
[H]\C1=C([H])\[C@@]2([H])O[C@@]3([H])C[C@@]4([H])O[C@]([H])(CC(=C)C=O)C[C@]([H])(O)[C@]4(C)O[C@]3([H])C[C@]2([H])O[C@]2([H])C[C@]3(C)O[C@]4(C)CC[C@]5([H])O[C@]6([H])C[C@]7(C)O[C@]8([H])C(C)=CC(=O)O[C@@]8([H])C[C@@]7([H])O[C@@]6([H])C[C@@]([H])(C)[C@@]5([H])O[C@@]4([H])C[C@@]3([H])O[C@@]2([H])C1
C49H68O14
InChI=1S/C49H68O14/c1-24(23-50)13-27-16-38(51)49(7)42(53-27)18-33-34(61-49)17-32-28(54-33)9-8-10-29-36(56-32)22-48(6)41(57-29)20-40-46(4,63-48)12-11-30-44(60-40)25(2)14-31-37(55-30)21-47(5)39(58-31)19-35-45(62-47)26(3)15-43(52)59-35/h8-9,15,23,25,27-42,44-45,51H,1,10-14,16-22H2,2-7H3/b9-8-/t25-,27-,28-,29+,30+,31+,32+,33+,34-,35+,36-,37-,38+,39-,40+,41-,42-,44-,45-,46-,47+,48+,49+/m1/s1
InChIKey=WTXGTTBOKVQBGS-ZOTXBKINSA-N
881.0558
880.460906884
Exogenous
Solid
CHEMBL1077122
24684127