Browsing Toxins
Displaying toxin 276 - 300 of 3678 in total
T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
---|---|---|---|---|---|
T3D0071 | Toluene 108-88-3 | C7H8 92.138 g/mol |
| Toluene is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinesteras...more Number of Targets: 39 | |
T3D2751 | Tolcapone 134308-13-7 | C14H11NO5 273.241 g/mol |
| Tolcapone hepatoxicity can be attributed to elevated levels of transminases, but studies have shown that minimal risk exists for those without preexisting liver condit...more Number of Targets: 1 | |
T3D4765 | Tolazamide 1156-19-0 | C14H21N3O3S 311.400 g/mol |
| Sulfonylureas likely bind to ATP-sensitive potassium-channel receptors on the pancreatic cell surface, reducing potassium conductance and causing depolarization of the...more Number of Targets: 3 | |
T3D4572 | Tofisopam 22345-47-7 | C22H26N2O4 382.453 g/mol |
| Tofisopam does not bind to the benzodiazepine binding site of the gamma-aminobutyric acid receptor. One study (Rundfeldt C. et al.) has shown that tofisopam acts as an...more Number of Targets: 22 | |
T3D2862 | Tizanidine 51322-75-9 | C9H8ClN5S 253.711 g/mol |
| Tizanidine reduces spasticity by increasing presynaptic inhibition of motor neurons through agonist action at a2-adrenergic receptor sites. Number of Targets: 4 | |
T3D2526 | Tityustoxin (Tityus serrulatus ) 39465-37-7 | Not Available 6997.935 g/mol |
| Tityustoxin binds to voltage-dependent sodium and potassium channels. alpha-Type tityustoxin inhibits the inactivation of the activated sodium channels by binding to s...more Number of Targets: 14 | |
T3D2414 | Titanium(III) phosphide 12037-65-9 | PTi 78.841 g/mol |
| Phosphine inhibits cytochrome c oxidase, preventing mitochondrial oxidative phosphorylation. This non-competitive inhibition prevents cellular respiration and leads to...more Number of Targets: 20 | |
T3D1765 | Titanium tetrabromide 7789-68-6 | Br4Ti 367.483 g/mol |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 | |
T3D1543 | Titanium aluminide 12003-96-2 | AlTi 74.849 g/mol |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 | |
T3D4983 | Tiratricol 51-24-1 | C14H9I3O4 621.932 g/mol |
| Tiratricol is a naturally occurring metabolite of T4 (thyroxine) and a structural analog of T3 (triiodothyronine). Low concentrations of tiratricol are found in plasma...more Number of Targets: 1 | |
T3D4770 | Tioguanine 154-42-7 | C5H5N5S 167.192 g/mol |
| Thioguanine competes with hypoxanthine and guanine for the enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRTase) and is itself converted to 6-thioguanilyic ...more Number of Targets: 6 | |
T3D2956 | Tioconazole 65899-73-2 | C16H13Cl3N2OS 387.711 g/mol |
| Tioconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In this wa...more Number of Targets: 2 | |
T3D1016 | Tiocarbazil 36756-79-3 | C16H25NOS 279.441 g/mol |
| Some thiocarbamates (EPTC, Molinate, Pebulate, and Cycloate) share a common mechanism of toxicity, i.e. the inhibition of acetylcholinesterase. An acetylcholinesterase...more Number of Targets: 2 | |
T3D1279 | Tin(IV) sulfide 1315-01-1 | S2Sn 182.840 g/mol |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 | |
T3D1234 | Tin(IV) oxide 18282-10-5 | O2Sn 150.710 g/mol |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 | |
T3D1278 | Tin(IV) iodide 7790-47-8 | I4Sn 626.330 g/mol |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 | |
T3D1277 | Tin(IV) fluoride 7783-62-2 | F4Sn 194.700 g/mol |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 | |
T3D1274 | Tin(IV) bromide 7789-67-5 | Br4Sn 438.330 g/mol |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 13 | |
T3D1273 | Tin(II) sulfide 1314-95-0 | SSn 150.770 g/mol |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 | |
T3D1272 | Tin(II) sulfate 7488-55-3 | O4SSn 214.770 g/mol |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 | |
T3D1271 | Tin(II) oxide 21651-19-4 | OSn 134.710 g/mol |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 | |
T3D1270 | Tin(II) iodide 10294-70-9 | I2Sn 372.520 g/mol |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 | |
T3D1269 | Tin(II) hydroxide 12026-24-3 | H2O2Sn 152.720 g/mol |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 | |
T3D1236 | Tin(II) fluoroborate 13814-97-6 | B2F8Sn 292.320 g/mol |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 | |
T3D1237 | Tin(II) fluoride 7783-47-3 | F2Sn 156.710 g/mol |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 |