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Displaying toxin 3501 - 3525 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D22051,3,6,8-Tetrachlorodibenzofuran
71998-72-6
C12H4Cl4O
305.972 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D20861,3,6,8-Tetrachlorodibenzo-p-dioxin
33423-92-6
C12H4Cl4O2
321.971 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Chlorinated Dibenzo-p-dioxin
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more
Number of Targets: 4
T3D22041,3,6,7-Tetrachlorodibenzofuran
57117-36-9
C12H4Cl4O
305.972 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D01031,3,5-Trinitrobenzene
99-35-4
C6H3N3O6
213.105 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Explosive Agent
  • Industrial/Workplace Toxin
  • Nitrite
  • Organic Compound
  • Synthetic Compound
In the red blood cell, 1,3,5-TNB induces formation of methemoglobin, leading to cyanosis. Reduction of the nitrogroup(s) of 1,3,5-TNB produces reactive nitroaromatic r...more
Number of Targets: 0
T3D07841,3,5-Trichlorobenzene
108-70-3
C6H3Cl3
181.447 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pesticide
  • Solvent
  • Synthetic Compound
Trichlorobenzene may uncouple mitochondrial oxidative phosphorylation, inducing potassium ion release and inhibiting respiratory control. It's metabolites may covalent...more
Number of Targets: 38
T3D24281,3,4-Trichlorodibenzofuran
82911-61-3
C12H5Cl3O
271.527 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D24451,3,4,9-Tetrachlorodibenzofuran
83704-28-3
C12H4Cl4O
305.972 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D22011,3,4,8-Tetrachlorodibenzofuran
92341-04-3
C12H4Cl4O
305.972 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D21851,3,4,8,9-Pentachlorodibenzofuran
70872-82-1
C12H3Cl5O
340.417 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D22001,3,4,7-Tetrachlorodibenzofuran
70648-16-7
C12H4Cl4O
305.972 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D21991,3,4,7,9-Pentachlorodibenzofuran
70648-20-3
C12H3Cl5O
340.417 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D21981,3,4,7,8-Pentachlorodibenzofuran
58802-16-7
C12H3Cl5O
340.417 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D21971,3,4,6-Tetrachlorodibenzofuran
83704-27-2
C12H4Cl4O
305.972 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D21961,3,4,6,9-Pentachlorodibenzofuran
70648-15-6
C12H3Cl5O
340.417 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D21951,3,4,6,8-Pentachlorodibenzofuran
83704-55-6
C12H3Cl5O
340.417 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D21941,3,4,6,7-Pentachlorodibenzofuran
83704-36-3
C12H3Cl5O
340.417 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D21931,3,4,6,7,9-Hexachlorodibenzofuran
92341-05-4
C12H2Cl6O
374.862 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D21921,3,4,6,7,8-Hexachlorodibenzofuran
71998-75-9
C12H2Cl6O
374.862 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D46361,2-Naphthoquinone
524-42-5
C10H6O2
158.153 g/mol
Thumb
  • Cigarette Toxin
  • Ester
  • Fuel
  • Organic Compound
  • Pollutant
  • Synthetic Compound
1,2-Naphthoquinone is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylch...more
Number of Targets: 10
T3D01671,2-Diphenylhydrazine
122-66-7
C12H12N2
184.237 g/mol
Thumb
  • Amine
  • Aromatic Hydrocarbon
  • Hydrazine
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
Two of the known metabolites, aniline and benzidine, may contribute to the toxicity and/or carcinogenicity of 1,2-diphenylhydrazine. Nonneoplastic liver lesions, hepat...more
Number of Targets: 3
T3D19091,2-Dichloropropene
563-54-2
C3H4Cl2
110.970 g/mol
Thumb
  • Chloropropene
  • Food Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Metabolism of 1,2-D in the rat results in the formation of a mercapturic acid conjugate excreted largely in the urine. Proposed reactive intermediates include 1,2-epox...more
Number of Targets: 3
T3D00851,2-Dichloroethane
107-06-2
C2H4Cl2
98.959 g/mol
Thumb
  • Food Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Organochloride
  • Pollutant
  • Solvent
  • Synthetic Compound
1,2-Dichloroethane is metabolized to 2-chloroacetaldehyde, S-(2-chloroethyl)glutathione by conjugation with glutathione, and to other putative reactive intermediates c...more
Number of Targets: 39
T3D21911,2-Dichlorodibenzofuran
64126-85-8
C12H6Cl2O
237.081 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D20541,2-Dichlorodibenzo-p-dioxin
54536-18-4
C12H6Cl2O2
253.081 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Chlorinated Dibenzo-p-dioxin
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more
Number of Targets: 4
T3D01721,2-Dichlorobenzene
95-50-1
C6H4Cl2
147.002 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Food Toxin
  • Household Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Solvent
  • Synthetic Compound
1,2-DCB was found to covalently bind to DNA, RNA, and proteins of liver, kidney, lung, and stomach. (L395)
Number of Targets: 42
Displaying toxin 3501 - 3525 of 3678 in total