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Browsing Toxins
Displaying toxin 3501 - 3525 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2205 | 1,3,6,8-Tetrachlorodibenzofuran 71998-72-6 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2086 | 1,3,6,8-Tetrachlorodibenzo-p-dioxin 33423-92-6 | C12H4Cl4O2 321.971 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2204 | 1,3,6,7-Tetrachlorodibenzofuran 57117-36-9 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D0103 | 1,3,5-Trinitrobenzene 99-35-4 | C6H3N3O6 213.105 g/mol |  |
| In the red blood cell, 1,3,5-TNB induces formation of methemoglobin, leading to cyanosis. Reduction of the nitrogroup(s) of 1,3,5-TNB produces reactive nitroaromatic r...more Number of Targets: 0 |
| T3D0784 | 1,3,5-Trichlorobenzene 108-70-3 | C6H3Cl3 181.447 g/mol |  |
| Trichlorobenzene may uncouple mitochondrial oxidative phosphorylation, inducing potassium ion release and inhibiting respiratory control. It's metabolites may covalent...more Number of Targets: 38 |
| T3D2428 | 1,3,4-Trichlorodibenzofuran 82911-61-3 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2445 | 1,3,4,9-Tetrachlorodibenzofuran 83704-28-3 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2201 | 1,3,4,8-Tetrachlorodibenzofuran 92341-04-3 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2185 | 1,3,4,8,9-Pentachlorodibenzofuran 70872-82-1 | C12H3Cl5O 340.417 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2200 | 1,3,4,7-Tetrachlorodibenzofuran 70648-16-7 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2199 | 1,3,4,7,9-Pentachlorodibenzofuran 70648-20-3 | C12H3Cl5O 340.417 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2198 | 1,3,4,7,8-Pentachlorodibenzofuran 58802-16-7 | C12H3Cl5O 340.417 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2197 | 1,3,4,6-Tetrachlorodibenzofuran 83704-27-2 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2196 | 1,3,4,6,9-Pentachlorodibenzofuran 70648-15-6 | C12H3Cl5O 340.417 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2195 | 1,3,4,6,8-Pentachlorodibenzofuran 83704-55-6 | C12H3Cl5O 340.417 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2194 | 1,3,4,6,7-Pentachlorodibenzofuran 83704-36-3 | C12H3Cl5O 340.417 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2193 | 1,3,4,6,7,9-Hexachlorodibenzofuran 92341-05-4 | C12H2Cl6O 374.862 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2192 | 1,3,4,6,7,8-Hexachlorodibenzofuran 71998-75-9 | C12H2Cl6O 374.862 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D4636 | 1,2-Naphthoquinone 524-42-5 | C10H6O2 158.153 g/mol |  |
| 1,2-Naphthoquinone is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylch...more Number of Targets: 10 |
| T3D0167 | 1,2-Diphenylhydrazine 122-66-7 | C12H12N2 184.237 g/mol |  |
| Two of the known metabolites, aniline and benzidine, may contribute to the toxicity and/or carcinogenicity of 1,2-diphenylhydrazine. Nonneoplastic liver lesions, hepat...more Number of Targets: 3 |
| T3D1909 | 1,2-Dichloropropene 563-54-2 | C3H4Cl2 110.970 g/mol |  |
| Metabolism of 1,2-D in the rat results in the formation of a mercapturic acid conjugate excreted largely in the urine. Proposed reactive intermediates include 1,2-epox...more Number of Targets: 3 |
| T3D0085 | 1,2-Dichloroethane 107-06-2 | C2H4Cl2 98.959 g/mol |  |
| 1,2-Dichloroethane is metabolized to 2-chloroacetaldehyde, S-(2-chloroethyl)glutathione by conjugation with glutathione, and to other putative reactive intermediates c...more Number of Targets: 39 |
| T3D2191 | 1,2-Dichlorodibenzofuran 64126-85-8 | C12H6Cl2O 237.081 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2054 | 1,2-Dichlorodibenzo-p-dioxin 54536-18-4 | C12H6Cl2O2 253.081 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D0172 | 1,2-Dichlorobenzene 95-50-1 | C6H4Cl2 147.002 g/mol |  |
| 1,2-DCB was found to covalently bind to DNA, RNA, and proteins of liver, kidney, lung, and stomach. (L395) Number of Targets: 42 |