You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on Toxin, Toxin Target Database.
Browsing Toxins
Displaying toxin 3526 - 3550 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1796 | 1,2-Dibromopropane 78-75-1 | C3H6Br2 201.888 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 0 |
| T3D0035 | 1,2-Dibromoethane 106-93-4 | C2H4Br2 187.861 g/mol |  |
| The metabolite 2-bromoacetaldehyde produces liver damage by binding to cellular proteins. S-(2-bromoethyl)glutathione, another metabolite, exerts genotoxic and carcino...more Number of Targets: 5 |
| T3D0044 | 1,2-Dibromo-3-chloropropane 96-12-8 | C3H5Br2Cl 236.333 g/mol |  |
| The initial metabolism of 1,2-dibromo-3-chloropropane to reactive epoxide metabolites that bind to DNA and other macromolecules may be responsible for its hepatotoxici...more Number of Targets: 54 |
| T3D1304 | 1,2-Bis(dimethylarsino)benzene 13246-32-7 | C10H16As2 286.077 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D4861 | 1,2-Benzisothiazol-3(2H)-one 2634-33-5 | C7H5NOS 151.186 g/mol |  |
| Not Available Number of Targets: 6 |
| T3D2427 | 1,2,9-Trichlorodibenzofuran 83704-38-5 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2067 | 1,2,9-Trichlorodibenzo-p-dioxin 82291-32-5 | C12H5Cl3O2 287.526 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2426 | 1,2,8-Trichlorodibenzofuran 83704-34-1 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2068 | 1,2,8-Trichlorodibenzo-p-dioxin 82291-31-4 | C12H5Cl3O2 287.526 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2444 | 1,2,8,9-Tetrachlorodibenzofuran 70648-22-5 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2085 | 1,2,8,9-Tetrachlorodibenzo-p-dioxin 62470-54-6 | C12H4Cl4O2 321.971 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2425 | 1,2,7-Trichlorodibenzofuran 83704-37-4 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2069 | 1,2,7-Trichlorodibenzo-p-dioxin 82291-30-3 | C12H5Cl3O2 287.526 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2190 | 1,2,7,9-Tetrachlorodibenzofuran 83704-26-1 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2189 | 1,2,7,8-Tetrachlorodibenzofuran 58802-20-3 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2188 | 1,2,7,8-Tetrabromodibenzofuran 84761-80-8 | C12H4Br4O 483.776 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2424 | 1,2,6-Trichlorodibenzofuran 64560-15-2 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2070 | 1,2,6-Trichlorodibenzo-p-dioxin 69760-96-9 | C12H5Cl3O2 287.526 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2443 | 1,2,6,9-Tetrachlorodibenzofuran 70648-18-9 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2083 | 1,2,6,9-Tetrachlorodibenzo-p-dioxin 40581-91-7 | C12H4Cl4O2 321.971 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2187 | 1,2,6,8-Tetrachlorodibenzofuran 83710-07-0 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2082 | 1,2,6,8-Tetrachlorodibenzo-p-dioxin 67323-56-2 | C12H4Cl4O2 321.971 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2186 | 1,2,6,7-Tetrachlorodibenzofuran 83704-25-0 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2081 | 1,2,6,7-Tetrachlorodibenzo-p-dioxin 40581-90-6 | C12H4Cl4O2 321.971 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D4877 | 1,2,4-Trimethylbenzene 95-63-6 | C9H12 120.192 g/mol |  |
| Not Available Number of Targets: 1 |