Tmic
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Displaying toxins 76 - 100 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D2699Vitamin A
68-26-8
C20H30O
286.452 g/mol
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  • Anti-Acne Preparation
  • Drug
  • Essential Vitamin
  • Food Toxin
  • Household Toxin
  • Metabolite
  • Natural Compound
  • Nutraceutical
  • Organic Compound
  • Selective Serotonin Reuptake Inhibitor
  • Vitamin
  • Vitamin A
Vision:Vitamin A (all-trans retinol) is converted in the retina to the 11-cis-isomer of retinaldehyde or 11-cis-retinal. 11-cis-retinal functions in the retina in the ...more
Number of Targets: 32
T3D2643Vipoxin
Not Available
Not Available
13827.665 g/mol
T3d2643
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
Vipoxin inhibits the binding of ligands to biogenic amine receptors including dopamine, serotonin and alpha1/alpha2 adrenergic receptors. Vipoxin also exhibits hemoly...more
Number of Targets: 28
T3D2642Viperotoxin
Not Available
Not Available
15554.775 g/mol
T3d2642
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
Viperotoxin is a presynaptic neurotoxin. (T170)
Number of Targets: 0
T3D0004Vinyl chloride
75-01-4
C2H3Cl
62.498 g/mol
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  • Cigarette Toxin
  • Household Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
Vinyl chloride poisoning exhibits many of the characteristics of autoimmune diseases. This is believed to be the result of a reactive vinyl chloride intermediate metab...more
Number of Targets: 43
T3D1806Vinyl bromide
593-60-2
C2H3Br
106.949 g/mol
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  • Bromide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Pollutant
  • Synthetic Compound
Organobromide compounds, especially alkylbromides are strong alkylating agents. Consequently they can randomly modify the surfaces of proteins and lipids, leading to ...more
Number of Targets: 2
T3D2479Vindesine
53643-48-4
C43H55N5O7
753.926 g/mol
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  • Amide
  • Amine
  • Antineoplastic Agent
  • Antineoplastic Agent, Phytogenic
  • Drug
  • Ester
  • Ether
  • Metabolite
  • Organic Compound
  • Synthetic Compound
  • Tubulin Modulator
Vindesine acts by causing the arrest of cells in metaphase mitosis through its inhibition tubulin mitotic funcitoning. The drug is cell-cycle specific for the S phase.
Number of Targets: 1
T3D4016Vincristine
57-22-7
C46H56N4O10
824.958 g/mol
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  • Amide
  • Amine
  • Antineoplastic Agent, Phytogenic
  • Drug
  • Ester
  • Ether
  • Metabolite
  • Organic Compound
  • Synthetic Compound
  • Tubulin Modulator
The antitumor activity of Vincristine is thought to be due primarily to inhibition of mitosis at metaphase through its interaction with tubulin. Like other vinca alkal...more
Number of Targets: 7
T3D3942Vinclozolin
50471-44-8
C12H9Cl2NO3
286.111 g/mol
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  • Amide
  • Amine
  • Carbamate
  • Ester
  • Ether
  • Fungicide
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Vinclozolin and some of its metabolites have antiandrogenic activity. Vinclozolin's main toxic effects are related to its antiandrogenic activity. They compete with an...more
Number of Targets: 11
T3D4017Vinblastine
865-21-4
C46H58N4O9
810.974 g/mol
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  • Amine
  • Antineoplastic Agent, Phytogenic
  • Drug
  • Ester
  • Ether
  • Metabolite
  • Organic Compound
  • Synthetic Compound
  • Tubulin Modulator
The antitumor activity of vinblastine is thought to be due primarily to inhibition of mitosis at metaphase through its interaction with tubulin. Vinblastine binds to t...more
Number of Targets: 6
T3D2977Vigabatrin
60643-86-9
C6H11NO2
129.157 g/mol
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  • Amine
  • Anticonvulsant
  • Drug
  • Enzyme Inhibitor
  • GABA Agent
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Vigabatrin increases brain concentrations of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the CNS, by irreversibly inhibiting enzymes that catabol...more
Number of Targets: 2
T3D2496Versutoxin
114264-83-4
Not Available
4855.645 g/mol
T3d2496
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Versutoxin inhibits both insect and mammalian voltage-gated sodium channels. It binds to site 3 in tetrodotoxin-sensitive sodium channels, which slows their inactivati...more
Number of Targets: 14
T3D3782Verruculogen
12771-72-1
C27H33N3O7
511.567 g/mol
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  • Amide
  • Amine
  • Ether
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more
Number of Targets: 28
T3D3781Verrucosidin
88389-71-3
C24H32O6
416.507 g/mol
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  • Ester
  • Ether
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more
Number of Targets: 23
T3D3723Verrucarol
2198-92-7
C15H22O4
266.333 g/mol
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  • Ether
  • Fungal Toxin
  • Lachrymator
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more
Number of Targets: 2
T3D3722Verrucarin J
4643-58-7
C27H32O8
484.538 g/mol
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  • Ester
  • Ether
  • Fungal Toxin
  • Lachrymator
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more
Number of Targets: 2
T3D3721Verrucarin B
2290-11-1
C27H32O9
500.538 g/mol
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  • Ester
  • Ether
  • Fungal Toxin
  • Lachrymator
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more
Number of Targets: 2
T3D3720Verrucarin A
3148-09-2
C27H34O9
502.554 g/mol
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  • Ester
  • Ether
  • Fungal Toxin
  • Lachrymator
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more
Number of Targets: 2
T3D1020Vernolate
1929-77-7
C10H21NOS
203.345 g/mol
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  • Carbamate
  • Ether
  • Herbicide
  • Organic Compound
  • Synthetic Compound
Some thiocarbamates (EPTC, Molinate, Pebulate, and Cycloate) share a common mechanism of toxicity, i.e. the inhibition of acetylcholinesterase. An acetylcholinesterase...more
Number of Targets: 4
T3D4061Veratridine
71-62-5
C36H51NO11
673.790 g/mol
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  • Amine
  • Ester
  • Ether
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Veratridine is a steroid-derived alkaloid from plants in the Liliaceae family that functions as a neurotoxin by abolishing inactivation of sodium ion channels. It bind...more
Number of Targets: 0
T3D4084Veratramine
60-70-8
C27H39NO2
409.604 g/mol
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  • Amine
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Veratramine produces a characteristic excitatory action on the central nervous system, producing both tremor and a characteristic "struggling" behavior. This behaviora...more
Number of Targets: 0
T3D3544Verapamil
52-53-9
C27H38N2O4
454.602 g/mol
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  • Amine
  • Anti-Arrhythmia Agent
  • Calcium Channel Blocker
  • Cyanide Compound
  • Drug
  • Ether
  • Food Toxin
  • Metabolite
  • Nitrile
  • Organic Compound
  • Synthetic Compound
  • Vasodilator Agent
Verapamil inhibits voltage-dependent calcium channels. Specifically, its effect on L-type calcium channels in the heart causes a reduction in ionotropy and chronotropy...more
Number of Targets: 21
T3D2736Venlafaxine
93413-69-5
C17H27NO2
277.402 g/mol
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  • Amine
  • Analgesic
  • Antidepressant
  • Antidepressant, Second-Generation
  • Antidepressive Agent
  • Drug
  • Ether
  • Food Toxin
  • Metabolite
  • Organic Compound
  • Serotonin Uptake Inhibitor
  • Synthetic Compound
The exact mechanism of action of venlafaxine is unknown, but appears to be associated with the its potentiation of neurotrasmitter activity in the CNS. Venlafaxine and...more
Number of Targets: 19
T3D2577Varenicline
249296-44-4
C13H13N3
211.262 g/mol
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  • Amine
  • Drug
  • Metabolite
  • Nicotinic Agonist
  • Organic Compound
  • Synthetic Compound
Varenicline is an alpha-4 beta-2 neuronal nicotinic acetylcholine receptor partial agonist. The drug shows high selectiviyty for this receptor subclass, relative to ot...more
Number of Targets: 4
T3D3067Vapreotide
103222-11-3
C57H70N12O9S2
1131.371 g/mol
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  • Amide
  • Amine
  • Analgesic
  • Antineoplastic Agent
  • Drug
  • Metabolite
  • Organic Compound
  • Synthetic Compound
The exact mechanism of action is unknown, although one study has provided in vitro and in vivo evidence for a tachykinin NK1 receptor antagonist effect in the analgesi...more
Number of Targets: 3
T3D4849Vanillin
121-33-5
C8H8O3
152.147 g/mol
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  • Ester
  • Ether
  • Flavouring Agent
  • Food Additive
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Synthetic Compound
Not Available
Number of Targets: 1
Displaying toxins 76 - 100 of 3678 in total