Browsing Toxins
Displaying toxin 3201 - 3225 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3580 | Sodium fluoroacetate 62-74-8 | C2H2FNaO2 100.024 g/mol |  |
| Fluoroacetate is similar to acetate, which has a pivotal role in cellular metabolism. Fluoroacetate disrupts the citric acid cycle by combining with coenzyme A to form...more Number of Targets: 0 |
| T3D1533 | Sodium hexafluoroaluminate 13775-53-6 | AlF6Na3 209.941 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D1882 | Sodium hexafluoroantimonate 16925-25-0 | F6NaSb 258.740 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D4970 | Sodium hypochlorite 7681-52-9 | ClNaO 74.442 g/mol |  |
| Sodium hypochlorite is a strong oxidizer. Oxidation reactions are corrosive, solutions burn skin and cause eye damage, especially when used in concentrated forms. In p...more Number of Targets: 0 |
| T3D3630 | Sodium laureth sulfate 9004-82-4 | C14H29NaO5S 332.432 g/mol |  |
| While sodium laureth sulfate itself is not toxic, it is a nitrosating agent. Nitrosating agents may decompose and/or react to cause nitrosamine contamination. Nitrosam...more Number of Targets: 3 |
| T3D3624 | Sodium lauroyl sarcosinate 137-16-6 | C15H28NNaO3 293.378 g/mol |  |
| While acyl sarcosines themselves are not toxic, they are nitrosating agents. Nitrosating agents may decompose and/or react to cause nitrosamine contamination. Nitrosam...more Number of Targets: 2 |
| T3D3629 | Sodium lauryl sulfate 151-21-3 | C12H25NaO4S 288.379 g/mol |  |
| While sodium lauryl sulfate itself is not toxic, it is a nitrosating agent. Nitrosating agents may decompose and/or react to cause nitrosamine contamination. Nitrosami...more Number of Targets: 13 |
| T3D1646 | Sodium metavanadate 13718-26-8 | NaO3V 121.930 g/mol |  |
| Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impairing the cells' phagocytotic ability and viability. The pentavalent fo...more Number of Targets: 47 |
| T3D3574 | Sodium nitrate 7631-99-4 | NNaO3 84.995 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 11 |
| T3D3551 | Sodium nitrite 7632-00-0 | NNaO2 68.995 g/mol |  |
| Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and methemoglobin. This elevation of methemoglobin levels is a condition known as meth...more Number of Targets: 9 |
| T3D0768 | Sodium nitroprusside 14402-89-2 | C5FeN6Na2O 261.918 g/mol |  |
| Sodium nitroprusside is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetyl...more Number of Targets: 40 |
| T3D1647 | Sodium orthovanadate 13721-39-6 | Na3O4V 183.908 g/mol |  |
| Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impairing the cells' phagocytotic ability and viability. The pentavalent fo...more Number of Targets: 47 |
| T3D1915 | Sodium perchlorate 7601-89-0 | ClNaO4 122.440 g/mol |  |
| The primary and most sensitive target of the perchlorate anion (perchlorate) is the thyroid gland. Perchlorate inhibits the transport of iodide (I-) from the blood int...more Number of Targets: 12 |
| T3D1155 | Sodium permanganate 10101-50-5 | MnNaO4 141.925 g/mol |  |
| Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particu...more Number of Targets: 5 |
| T3D2413 | Sodium phosphide 12058-85-4 | Na3P 99.943 g/mol |  |
| Phosphine inhibits cytochrome c oxidase, preventing mitochondrial oxidative phosphorylation. This non-competitive inhibition prevents cellular respiration and leads to...more Number of Targets: 20 |
| T3D1816 | Sodium selenate 13410-01-0 | Na2O4Se 188.940 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 4 |
| T3D1839 | Sodium selenite 10102-18-8 | Na2O3Se 172.940 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 0 |
| T3D1594 | Sodium tetrachloro-palladate(II) 13820-53-6 | Cl4Na2Pd 294.210 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D4742 | Sodium Tetradecyl Sulfate 1191-50-0 | C14H30O4S 294.451 g/mol |  |
| Sodium tetradecyl sulfate is a potent toxin for endothelial cells in that brief exposure to even low concentrations are effective in stripping endothelium over a consi...more Number of Targets: 18 |
| T3D1883 | Sodium thioantimonate(V) 13776-84-6 | Na3S4Sb 318.990 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D1161 | Sodium uranate 13721-34-1 | Na2O7U2 634.033 g/mol |  |
| Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and prot...more Number of Targets: 1 |
| T3D1469 | Sodium zincate 12179-14-5 | H4Na2O4Zn 179.418 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |
| T3D3533 | Sorafenib 284461-73-0 | C21H16ClF3N4O3 464.825 g/mol |  |
| Sorafenib interacts with multiple intracellular (CRAF, BRAF and mutant BRAF) and cell surface kinases (KIT, FLT-3, VEGFR-2, VEGFR-3, and PDGFR-ß). Several of these kin...more Number of Targets: 18 |
| T3D4854 | Sorbitan oleate 1338-43-8 | C24H44O6 428.603 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D4167 | Spermidine 124-20-9 | C7H19N3 145.246 g/mol |  |
| Uremic toxins such as spermidine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimul...more Number of Targets: 17 |