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Displaying toxin 3226 - 3250 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D4166Spermine
71-44-3
C10H26N4
202.340 g/mol
Thumb
  • Amine
  • Dietary Supplement
  • Drug
  • Food Toxin
  • Metabolite
  • Micronutrient
  • Natural Compound
  • Nutraceutical
  • Organic Compound
  • Supplement
  • Uremic Toxin
Uremic toxins such as spermine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimulat...more
Number of Targets: 21
T3D2630Sphingomyelinase D (Loxosceles intermedia)
9031-54-3
Not Available
34158.125 g/mol
T3d2630
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Sphingomyelinase D catalyzes the hydrolysis of sphingomyelin, inducing complement-dependent haemolysis, dermonecrosis, blood vessel permeability and platelet aggregati...more
Number of Targets: 0
T3D0819Sphondin
483-66-9
C12H8O4
216.190 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Ester
  • Ether
  • Food Toxin
  • Furocoumarin
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Sphondin possesses an inhibitory effect on IL-1b-induced COX-2 protein expression and PGE2 release in human pulmonary epithelial cell line (A549). The mechanism of act...more
Number of Targets: 3
T3D4536Spirodiclofen
148477-71-8
C21H24Cl2O4
411.319 g/mol
Thumb
  • Acaricide
  • Ester
  • Ether
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Not Available
Number of Targets: 19
T3D4753Spironolactone
52-01-7
C24H32O4S
416.573 g/mol
Thumb
  • Diuretic
  • Drug
  • Ester
  • Ether
  • Metabolite
  • Mineralocorticoid Receptor Antagonist
  • Organic Compound
  • Synthetic Compound
Spironolactone is a specific pharmacologic antagonist of aldosterone, acting primarily through competitive binding of receptors at the aldosterone-dependent sodium-pot...more
Number of Targets: 15
T3D3923Spiroxamine
118134-30-8
C18H35NO2
297.476 g/mol
Thumb
  • Amine
  • Fungicide
  • Organic Compound
  • Pesticide
  • Synthetic Compound
Not Available
Number of Targets: 20
T3D3776Sporidesmin
1456-55-9
C18H20ClN3O6S2
473.951 g/mol
Thumb
  • Amide
  • Amine
  • Ether
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
  • Organochloride
Sporidesmin and its reduced (dithiol) form undergo cyclic reduction/autoxidation reactions with glutathione and other thiols, generating toxic superoxide radicals, hyd...more
Number of Targets: 0
T3D1265Stannane
2406-52-2
H4Sn
122.740 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Synthetic Compound
  • Tin Compound
Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183)
Number of Targets: 7
T3D4772Stavudine
3056-17-5
C10H12N2O4
224.213 g/mol
Thumb
  • Amide
  • Anti-HIV Agent
  • Antimetabolite
  • Drug
  • Ether
  • Metabolite
  • Organic Compound
  • Reverse Transcriptase Inhibitor
  • Synthetic Compound
Stavudine inhibits the activity of HIV-1 reverse transcriptase (RT) both by competing with the natural substrate dGTP and by its incorporation into viral DNA.
Number of Targets: 1
T3D4755Stearic acid
57-11-4
C18H36O2
284.477 g/mol
Thumb
  • Animal Toxin
  • Food Toxin
  • Household Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Pharmaceutic Aid
  • Plant Toxin
Not Available
Number of Targets: 7
T3D3663Sterigmatocystin
10048-13-2
C18H12O6
324.284 g/mol
Thumb
  • Ester
  • Ether
  • Food Toxin
  • Fungal Toxin
  • Metabolite
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Sterigmatocystin's carcinogenic properties are a result of its ability to form guanyl DNA adducts and bind to DNA. In addition, DNA adduct formation causes enhanced pr...more
Number of Targets: 3
T3D0877Stibine
7803-52-3
H3Sb
124.780 g/mol
Thumb
  • Antimony Compound
  • Food Toxin
  • Inorganic Compound
  • Pollutant
  • Synthetic Compound
The inhalation data suggest that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes ...more
Number of Targets: 20
T3D2552Sticholysin
269658-04-0; 183449-91-4
Not Available
19390.885 g/mol
T3d2552
  • Amide
  • Amine
  • Animal Toxin
  • Marine Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Sticholysin is a cardiac stimulatory and hemolytic pore-forming protein. Pore formation likely proceeds by membrane binding via a surface rich in aromatic residues, fo...more
Number of Targets: 0
T3D2647Stonustoxin
Not Available
Not Available
79523.640 g/mol
No structure small
  • Amide
  • Amine
  • Animal Toxin
  • Marine Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Stonustoxin induces hemolytic activities due to its ability to form pores in the cell membrane. It is also myotoxic and interferes irreversibly with neuromuscular func...more
Number of Targets: 0
T3D4727Streptokinase
9002-01-1
Not Available
50139.695 g/mol
T3d4727
  • Amide
  • Amine
  • Bacterial Toxin
  • Fibrinolytic Agent
  • Natural Compound
  • Organic Compound
  • Protein
  • Thrombolytic Agent
Plasminogen is an inactive molecule that becomes activated to plasmin when the Arg/Val bond is cleaved. Plasmin breaks down fibrin clots created by the blood clotting ...more
Number of Targets: 2
T3D2622Streptolysin O (Streptococcus pyogenes)
98072-47-0
Not Available
63637.990 g/mol
T3d2622
  • Amide
  • Amine
  • Bacterial Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Streptolysin O binds to cholesterol on eukaryotic cell membranes, then is able to lyse them. (T170)
Number of Targets: 1
T3D2788Streptozocin
18883-66-4
C8H15N3O7
265.221 g/mol
Thumb
  • Amine
  • Antibiotic
  • Antibiotic, Antineoplastic
  • Antineoplastic Agent
  • Drug
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Streptozotocin is a naturally occurring chemical that is particularly toxic to the insulin-producing beta cells of the pancreas. It is used in medical research to prod...more
Number of Targets: 3
T3D2502Stromatoxin
1262235-00-6
Not Available
3798.295 g/mol
No structure small
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Stromatoxin blocks the delayed-rectifier type potassium channels Kv2.1, Kv2.2, Kv2.1/9.3 and the A-type potassium channel Kv4.2, with affinity (IC50) of 12.7 nM, 21.4 ...more
Number of Targets: 4
T3D1540Strontium aluminate
12004-37-4
Al2O5Sr2
309.200 g/mol
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  • Aluminum Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Pollutant
  • Synthetic Compound
The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more
Number of Targets: 3
T3D1317Strontium arsenite tetrahydrate
10378-48-0
As2H8O8Sr
373.520 g/mol
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  • Arsenic Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Pollutant
  • Synthetic Compound
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more
Number of Targets: 44
T3D1719Strontium bromate
14519-18-7
BrO3Sr
215.520 g/mol
Thumb
  • Bromate Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Pollutant
  • Synthetic Compound
Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more
Number of Targets: 6
T3D1756Strontium bromide
10476-81-0
Br2Sr
247.430 g/mol
Thumb
  • Bromide Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Pollutant
  • Synthetic Compound
Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more
Number of Targets: 6
T3D0712Strontium chromate
7789-06-2
CrO4Sr
203.610 g/mol
Thumb
  • Chromium Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Pollutant
  • Synthetic Compound
Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more
Number of Targets: 5
T3D3575Strontium nitrate
10042-76-9
N2O6Sr
211.630 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Nitrate
  • Nitrite
  • Pollutant
  • Synthetic Compound
Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more
Number of Targets: 9
T3D0120Strontium-90
10098-97-2
Sr
89.908 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Natural Compound
  • Pollutant
  • Radioactive
  • Radioactive Isotope
  • Strontium Compound
The fact that strontium is chemically similar to calcium allows it to exchange for calcium in bone. It affects bone development and strength by binding directly to hyd...more
Number of Targets: 1
Displaying toxin 3226 - 3250 of 3678 in total