Browsing Toxins
Displaying toxin 3326 - 3350 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1711 | Tetracyanoquinodimethane 1518-16-7 | C12H4N4 204.187 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D3955 | Tetracycline 60-54-8 | C22H24N2O8 444.435 g/mol |  |
| Tetracyclines target the 28S small subunit of the mitochondrial ribosome thereby deactivation mitochondrial protein synthesis. As a result tetracyclines are cytotoxic ...more Number of Targets: 7 |
| T3D0338 | Tetraethyl lead 78-00-2 | C8H20Pb 323.400 g/mol |  |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 29 |
| T3D4801 | Tetraethylene Glycol 112-60-7 | C8H18O5 194.226 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D1261 | Tetraethyltin 597-64-8 | C8H20Sn 234.950 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D1579 | Tetrakis(triphenylphosphine)palladium(0) 14221-01-3 | C72H64P4Pd 1159.590 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D1028 | Tetramethrin 7696-12-0 | C19H25NO4 331.406 g/mol |  |
| Both type I and type II pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to th...more Number of Targets: 28 |
| T3D0337 | Tetramethyl lead 75-74-1 | C4H12Pb 267.300 g/mol |  |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 29 |
| T3D1713 | Tetramethylsuccinonitrile 3333-52-6 | C8H12N2 136.194 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D1262 | Tetramethyltin 594-27-4 | C4H12Sn 178.850 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D1220 | Tetramminecopper(II) sulfate 10380-29-7 | CuH12N4O4S 227.731 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 6 |
| T3D1885 | Tetraphenylantimony bromide 16894-69-2 | C24H20BrSb 510.080 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D4587 | Tetrazepam 10379-14-3 | C16H17ClN2O 288.772 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 18 |
| T3D2484 | Tetrodotoxin 4368-28-9 | C11H17N3O8 319.268 g/mol |  |
| Tetrodotoxin binds to what is known as site 1 of the fast voltage-gated sodium channel. Site 1 is located at the extracellular pore opening of the ion channel. The bin...more Number of Targets: 14 |
| T3D3539 | Thalidomide 50-35-1 | C13H10N2O4 258.230 g/mol |  |
| In patients with erythema nodosum leprosum (ENL) the mechanism of action is not fully understood. Available data from in vitro studies and preliminary clinical trials ...more Number of Targets: 10 |
| T3D3975 | Thallium 7440-28-0 | Tl 204.383 g/mol |  |
| Thallium(I) compounds have a high aqueous solubility and are readily absorbed through the skin. Part of the reason for thallium's high toxicity is that, when present i...more Number of Targets: 22 |
| T3D1840 | Thallium selenide 12039-52-0 | O3SeTl2 535.720 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 0 |
| T3D1763 | Thallium(I) bromide 7789-40-4 | BrTl 284.287 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D4780 | Theophylline 58-55-9 | C7H8N4O2 180.164 g/mol |  |
| Theophylline relaxes the smooth muscle of the bronchial airways and pulmonary blood vessels and reduces airway responsiveness to histamine, methacholine, adenosine, an...more Number of Targets: 9 |
| T3D3931 | Thiabendazole 148-79-8 | C10H7N3S 201.248 g/mol |  |
| The precise mode of action of thiabendazole on the parasite is unknown, but it most likely inhibits the helminth-specific enzyme fumarate reductase. Number of Targets: 17 |
| T3D4540 | Thiacloprid 111988-49-9 | C10H9ClN4S 252.723 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 5 |
| T3D3932 | Thiamethoxam 153719-23-4 | C8H10ClN5O3S 291.715 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D2696 | Thiamine 59-43-8 | C12H17N4OS 265.354 g/mol |  |
| It is thought that the mechanism of action of thiamine on endothelial cells is related to a reduction in intracellular protein glycation by redirecting the glycolytic ...more Number of Targets: 4 |
| T3D1053 | Thiazolidine, 2-(nitromethylene) 94662-61-0 | C4H6N2O2S 146.168 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Number of Targets: 5 |
| T3D3933 | Thiazopyr 117718-60-2 | C16H17F5N2O2S 396.375 g/mol |  |
| Not Available Number of Targets: 12 |