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Browsing Toxins
Displaying toxin 3476 - 3500 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1550 | Triisobutylaluminum 100-99-2 | C12H27Al 198.324 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D1018 | Trimethacarb 2686-99-9 | C11H15NO2 193.242 g/mol |  |
| Trimethacarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sit...more Number of Targets: 2 |
| T3D2760 | Trimethadione 127-48-0 | C6H9NO3 143.141 g/mol |  |
| Dione anticonvulsants reduce T-type calcium currents in thalamic neurons, including thalamic relay neurons. It does so via the inhibition of voltage dependent T-type c...more Number of Targets: 1 |
| T3D1536 | Trimethylaluminium 75-24-1 | C3H9Al 72.085 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D4163 | Trimethylamine 75-50-3 | C3H9N 59.110 g/mol |  |
| Uremic toxins such as trimethylamine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can st...more Number of Targets: 3 |
| T3D4164 | Trimethylamine N-oxide 1184-78-7 | C3H9NO 75.110 g/mol |  |
| Uremic toxins such as TMAO are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimulate th...more Number of Targets: 3 |
| T3D1888 | Trimethylantimony bromide 5835-64-3 | C3H9Br2Sb 326.670 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 26 |
| T3D1889 | Trimethylantimony dichloride 13059-67-1 | C3H9Cl2Sb 237.770 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D1890 | Trimethylantimony diiodide 13077-53-7 | C3H9I2Sb 420.670 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D0305 | Trimethylarsine 593-88-4 | C3H9As 120.025 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D0318 | Trimethylarsine oxide 4964-14-1 | C3H9AsO 136.025 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D1891 | Trimethyloxonium hexachlorantimonate 54075-76-2 | C3H9Cl6OSb 395.580 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D0769 | Trimethylsilyl cyanide 7677-24-9 | C4H9NSi 99.207 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D1240 | Trimethyltin chloride 1066-45-1 | C3H9ClSn 199.270 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D3000 | Trimetrexate 52128-35-5 | C19H23N5O3 369.418 g/mol |  |
| In vitro studies have shown that trimetrexate is a competitive inhibitor of dihydrofolate reductase (DHFR) from bacterial, protozoan, and mammalian sources. DHFR catal...more Number of Targets: 2 |
| T3D2870 | Trimipramine 739-71-9 | C20H26N2 294.434 g/mol |  |
| Trimipramine's mechanism of action differs from other tricyclic antidepressants. Trimipramine acts by decreasing the reuptake of norepinephrine and serotonin (5-HT). Number of Targets: 17 |
| T3D1256 | Trioctyltin stannane 869-59-0 | C24H51Sn 458.370 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D1892 | Triphenylantimony 603-36-1 | C18H15Sb 353.070 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D1893 | Triphenylantimony diacetate 1538-62-1 | C22H21O4Sb 471.160 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D1894 | Triphenylantimony dibenzoate 57997-56-5 | C32H25O4Sb 595.300 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D1895 | Triphenylantimony dichloride 594-31-0 | C18H15Cl2Sb 423.980 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D1314 | Triphenylarsine 603-32-7 | C18H15As 306.233 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D1897 | Triphenylcarbenium hexachloroantimonate 52704-88-8 | C19H15Cl6Sb 577.800 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D0630 | Triphenylene 217-59-4 | C18H12 228.288 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 3 |
| T3D1896 | Triphenylthioantimonate 28609-58-7 | C18H15S3Sb 449.270 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |