Browsing Toxins
Displaying toxin 3251 - 3275 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0271 | Styrene 100-42-5 | C8H8 104.149 g/mol |  |
| Styrene 7,8-oxide, a metabolite of styrene, can form DNA adducts by binding to deoxyguanosine. It is also mutagenic and causes increased frequency of sister chromatid ...more Number of Targets: 1 |
| T3D4269 | 4-Hydroxybutyric acid 591-81-1 | C4H8O3 104.105 g/mol |  |
| GHB reaches much higher concentrations in the brain and activates GABAB receptors, which are primarily responsible for its sedative effects. GHB receptors are densely ...more Number of Targets: 2 |
| T3D0728 | Zinc fluoride 7783-49-5 | F2Zn 103.406 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |
| T3D4901 | Diethylenetriamine 111-40-0 | C4H13N3 103.166 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D1691 | Benzonitrile 100-47-0 | C7H5N 103.121 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D4250 | Gamma-Aminobutyric acid 56-12-2 | C4H9NO2 103.120 g/mol |  |
| Not Available Number of Targets: 10 |
| T3D1454 | Chromium trihydroxide 1308-14-1 | CrH3O3 103.018 g/mol |  |
| Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more Number of Targets: 5 |
| T3D1754 | Sodium bromide 7647-15-6 | BrNa 102.894 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 8 |
| T3D4900 | 1-Hexanol 111-27-3 | C6H14O 102.175 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4503 | Ethylenethiourea 96-45-7 | C3H6N2S 102.158 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D5001 | Succinic acid semialdehyde 692-29-5 | C4H6O3 102.089 g/mol |  | Not Available | Not Available Number of Targets: 0 |
| T3D1509 | Aluminium(III) oxide 1344-28-1 | Al2O3 101.961 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D1289 | Aluminium arsenide 22831-42-1 | AlAs 101.903 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 46 |
| T3D1191 | Copper(II) fluoride 7789-19-7 | CuF2 101.543 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 6 |
| T3D3572 | Potassium nitrate 7757-79-1 | KNO3 101.103 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 9 |
| T3D2410 | Gallium phosphide 12063-98-8 | GaP 100.697 g/mol |  |
| Phosphine inhibits cytochrome c oxidase, preventing mitochondrial oxidative phosphorylation. This non-competitive inhibition prevents cellular respiration and leads to...more Number of Targets: 20 |
| T3D3431 | N-Heptane 142-82-5 | C7H16 100.202 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D3432 | 2-Methylhexane 591-76-4 | C7H16 100.202 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D3433 | 3-Methylhexane 589-34-4 | C7H16 100.202 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D3434 | 2,2-Dimethylpentane 590-35-2 | C7H16 100.202 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D3435 | 2,3-Dimethylpentane 565-59-3 | C7H16 100.202 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D3436 | 2,4-Dimethylpentane 108-08-7 | C7H16 100.202 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D3437 | 3,3-Dimethylpentane 562-49-2 | C7H16 100.202 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D3438 | 3-Ethylpentane 617-78-7 | C7H16 100.202 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D3439 | 2,2,3-Trimethylbutane 464-06-2 | C7H16 100.202 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |