Browsing Toxins
Displaying toxin 3326 - 3350 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4360 | Glycerol 56-81-5 | C3H8O3 92.094 g/mol |  |
| Not Available Number of Targets: 12 |
| T3D3559 | Dinitrogen tetroxide 10544-72-6 | N2O4 92.011 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 9 |
| T3D0303 | Methylarsine 593-52-2 | CH5As 91.972 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D1387 | Cobalt sulfide 1317-42-6 | CoS 90.998 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D1412 | Nickel sulfide 11113-75-0 | NiS 90.758 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 68 |
| T3D4943 | 2-Ethoxyethanol 110-80-5 | C4H10O2 90.121 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4762 | 1,3-Butanediol 107-88-0 | C4H10O2 90.121 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4304 | Hydroxypropionic acid 503-66-2 | C3H6O3 90.078 g/mol |  |
| 3-hydroxypropionic acid (3HP) toxicity is mediated by 3-hydroxypropionic aldehyde (reuterin). 3HP toxicity is also proposed to be related to inhibition of the chorisma...more Number of Targets: 0 |
| T3D4307 | D-Lactic acid 10326-41-7 | C3H6O3 90.078 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D4964 | Glyceraldehyde 56-82-6 | C3H6O3 90.078 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4253 | L-Lactic acid 79-33-4 | C3H6O3 90.078 g/mol |  |
| Accumulation of L-lactic acid in the body has been shown to be toxic. At times of lactic acidosis, when excess intracellular lactate is released into the blood, mainte...more Number of Targets: 1 |
| T3D0856 | Oxalic acid 144-62-7 | C2H2O4 90.035 g/mol |  |
| The affinity of divalent metal ions is sometimes reflected in their tendency to form insoluble precipitates. Thus in the body, oxalic acid also combines with metals io...more Number of Targets: 6 |
| T3D0120 | Strontium-90 10098-97-2 | Sr 89.908 g/mol |  |
| The fact that strontium is chemically similar to calcium allows it to exchange for calcium in bone. It affects bone development and strength by binding directly to hyd...more Number of Targets: 1 |
| T3D0753 | Copper(I) cyanide 544-92-3 | CCuN 89.563 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 47 |
| T3D4841 | Dimethylethanolamine 108-01-0 | C4H11NO 89.136 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4320 | L-Alanine 56-41-7 | C3H7NO2 89.093 g/mol |  |
| L-Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar...more Number of Targets: 13 |
| T3D4583 | Ethyl carbamate 51-79-6 | C3H7NO2 89.093 g/mol |  |
| Ethyl carbamate is genotoxic and a potent carcinogen. It exerts its effects through the formation of DNA adducts (via its vinyl carbamate epoxide metabolite) that ind...more Number of Targets: 3 |
| T3D4346 | Beta-Alanine 107-95-9 | C3H7NO2 89.093 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D4458 | Sarcosine 107-97-1 | C3H7NO2 89.093 g/mol |  |
| Sarcosine is an oncometabolite. Sarcosine appears to upregulate the expression of the potent oncoprotein called human epidermal growth factor receptor 2 (HER2/neu) in ...more Number of Targets: 2 |
| T3D4169 | Putrescine 110-60-1 | C4H12N2 88.152 g/mol |  |
| Uremic toxins such as putrescine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimul...more Number of Targets: 7 |
| T3D4592 | Butyric acid 107-92-6 | C4H8O2 88.105 g/mol |  |
| Butyric acid is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholines...more Number of Targets: 10 |
| T3D0210 | 1,4-Dioxane 123-91-1 | C4H8O2 88.105 g/mol |  |
| Though the mechanism of toxicity of 1,4-dioxane has not yet been elucidated, it is known that its carcinogenic effects are caused by a non-genotoxic mechanism that is ...more Number of Targets: 4 |
| T3D1525 | Methylaluminoxane 120144-90-3 | C3H9AlO 88.085 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D4325 | Pyruvic acid 127-17-3 | C3H4O3 88.062 g/mol |  |
| Pyruvate serves as a biological fuel by being converted to acetyl coenzyme A, which enters the tricarboxylic acid or Krebs cycle where it is metabolized to produce ATP...more Number of Targets: 16 |
| T3D1675 | Ethyl thiocyanate 542-90-5 | C3H5NS 87.143 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |