Browsing Toxins
Displaying toxin 3376 - 3400 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1638 | Vanadium(IV) oxide 12036-21-4 | O2V 82.940 g/mol |  |
| Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impairing the cells' phagocytotic ability and viability. The pentavalent fo...more Number of Targets: 47 |
| T3D1190 | Copper(I) fluoride 13478-41-6 | CuF 82.544 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 6 |
| T3D1539 | Sodium aluminate 1302-42-7 | AlNaO2 81.970 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D0736 | Zinc oxide 1314-13-2 | OZn 81.408 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |
| T3D0776 | Potassium cyanate 590-28-3 | CKNO 81.115 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D1504 | Aluminium hydroxide 21645-51-2 | AlH6O3 81.027 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D1834 | Hydrogen selenide 7783-07-5 | H2Se 80.980 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 0 |
| T3D1732 | Hydrogen bromide 10035-10-6 | BrH 80.912 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D4685 | Chloromethyl methyl ether 107-30-2 | C2H5ClO 80.514 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D1486 | Aluminium chlorohydrate 1327-41-9 | AlClH2O 80.450 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D1710 | Succinonitrile 110-61-2 | C4H4N2 80.088 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D4466 | Sulfite 14265-45-3 | O3S 80.064 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D3552 | Ammonium nitrate 6484-52-2 | H4N2O3 80.043 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 9 |
| T3D0642 | Beryllium chloride 7787-47-5 | BeCl2 79.918 g/mol |  |
| Once in the body, beryllium acts as a hapten and interacts with human leucocyte antigen (HLA) DP presenting cells in the lungs, becoming physically associated with a m...more Number of Targets: 3 |
| T3D4971 | Bromide ion 24959-67-9 | Br 79.905 g/mol |  |
| The bromide ion is also known to affect the central nervous system, causing bromism. This is believed to be a result of bromide ions substituting for chloride ions in ...more Number of Targets: 23 |
| T3D1195 | Copper(II) oxide 1317-38-0 | CuO 79.545 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 6 |
| T3D0147 | Selenium 7782-49-2 | Se 78.960 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 0 |
| T3D2414 | Titanium(III) phosphide 12037-65-9 | PTi 78.841 g/mol |  |
| Phosphine inhibits cytochrome c oxidase, preventing mitochondrial oxidative phosphorylation. This non-competitive inhibition prevents cellular respiration and leads to...more Number of Targets: 20 |
| T3D4898 | Chloroacetaldehyde 107-20-0 | C2H3ClO 78.498 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D2982 | Dimethyl sulfoxide 67-68-5 | C2H6OS 78.133 g/mol |  |
| The mechanism of dimethyl sulfoxide's actions is not well understood. Dimethyl sulfoxide has demonstrated antioxidant activity in certain biological settings. For exam...more Number of Targets: 14 |
| T3D0006 | Benzene 71-43-2 | C6H6 78.112 g/mol |  |
| The toxic agents of benzene are its metabolites. Benzene is able increase its toxicity by inducing cytochrome P450 2E1, its main metabolic enzyme. Benzene's primary to...more Number of Targets: 101 |
| T3D3504 | Fluoroacetic acid 144-49-0 | C2H3FO2 78.042 g/mol |  |
| Fluoroacetate is similar to acetate, which has a pivotal role in cellular metabolism. Fluoroacetate disrupts the citric acid cycle by combining with coenzyme A to form...more Number of Targets: 2 |
| T3D0234 | Arsine 7784-42-1 | AsH3 77.945 g/mol |  |
| Arsine enters the bloodstream and crosses the alveolo-capillary membrane into red blood cells. Here it preferentially binds to hemoglobin and is oxidized to an arsenic...more Number of Targets: 10 |
| T3D2578 | Fluoroacetamide 640-19-7 | C2H4FNO 77.058 g/mol |  |
| Fluoroacetate produces its toxin action by inhibiting the citric acid cycle. The fluorine substituted acetate becomes incorporated, as a normal acetate, into fluoroace...more Number of Targets: 0 |
| T3D0696 | Nickel oxide 1313-99-1 | H2NiO 76.709 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 68 |