Browsing Toxins
Displaying toxin 3451 - 3475 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0730 | Zinc hydride 14018-82-7 | H2Zn 67.425 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |
| T3D1624 | Vanadium carbide 12070-10-9 | CH4V 66.984 g/mol |  |
| Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impairing the cells' phagocytotic ability and viability. The pentavalent fo...more Number of Targets: 47 |
| T3D1630 | Vanadium(II) oxide 12035-98-2 | OV 66.941 g/mol |  |
| Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impairing the cells' phagocytotic ability and viability. The pentavalent fo...more Number of Targets: 47 |
| T3D1704 | Malononitrile 109-77-3 | C3H2N2 66.061 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D1434 | Chromium nitride 24094-93-7 | CrN 66.003 g/mol |  |
| Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more Number of Targets: 5 |
| T3D1538 | Lithium aluminate 12003-67-7 | AlLiO2 65.921 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D0074 | Zinc 7440-66-6 | Zn 65.408 g/mol |  |
| Excessive zinc intake alters copper and iron absorption, most likely through competitive binding in intestinal mucosal cells. Stomach acid dissolves metallic zinc, pro...more Number of Targets: 28 |
| T3D0761 | Potassium cyanide 151-50-8 | CKN 65.116 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 42 |
| T3D1626 | Vanadium nitride 24646-85-3 | NV 64.948 g/mol |  |
| Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impairing the cells' phagocytotic ability and viability. The pentavalent fo...more Number of Targets: 47 |
| T3D0183 | Chloroethane 75-00-3 | C2H5Cl 64.514 g/mol |  |
| Chloroethane targets the central nervous system and the heart. The lipophilicity of chloroethane suggests it acts upon the lipid layer of cellular membrane or the hydr...more Number of Targets: 2 |
| T3D3548 | Ammonium nitrite 13446-48-5 | H4N2O2 64.044 g/mol |  |
| Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and methemoglobin. This elevation of methemoglobin levels is a condition known as meth...more Number of Targets: 9 |
| T3D0128 | Copper 7440-50-8 | Cu 63.545 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 20 |
| T3D3571 | Nitric acid 7697-37-2 | HNO3 63.013 g/mol |  |
| Nitric acid is a corrosive acid and a powerful oxidizing agent. The major hazard posed by it is chemical burns as it carries out acid hydrolysis with proteins (amide) ...more Number of Targets: 16 |
| T3D0004 | Vinyl chloride 75-01-4 | C2H3Cl 62.498 g/mol |  |
| Vinyl chloride poisoning exhibits many of the characteristics of autoimmune diseases. This is believed to be the result of a reactive vinyl chloride intermediate metab...more Number of Targets: 43 |
| T3D1512 | Aluminium monochloride 13595-81-8 | AlCl 62.435 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D0772 | Ethylene glycol 107-21-1 | C2H6O2 62.068 g/mol |  |
| Ethylene glycol is metabolized by alcohol dehydrogenase to glycoaldehyde, which is then metabolized to glycolic, glyoxylic, and oxalic acids. These acids, along with e...more Number of Targets: 0 |
| T3D0216 | Nitrate 14797-55-8 | NO3 62.005 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 16 |
| T3D3799 | Boric acid (H3BO3) 10043-35-3 | BH3O3 61.833 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D0756 | Cyanogen chloride 506-77-4 | CClN 61.470 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D4769 | Ethanolamine 141-43-5 | C2H7NO 61.083 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D4202 | Carbamic acid 463-77-4 | CH3NO2 61.040 g/mol |  |
| Carbamic acid is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholine...more Number of Targets: 1 |
| T3D4699 | Isopropyl alcohol 67-63-0 | C3H8O 60.095 g/mol |  |
| Not Available Number of Targets: 16 |
| T3D1568 | gamma-Aluminum oxide hydroxide 1318-23-6 | AlHO2 59.988 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D4973 | Cobalt-60 10198-40-0 | Co 59.934 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 38 |
| T3D4163 | Trimethylamine 75-50-3 | C3H9N 59.110 g/mol |  |
| Uremic toxins such as trimethylamine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can st...more Number of Targets: 3 |