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Displaying toxin 3476 - 3500 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D4172Guanidine
113-00-8
CH5N3
59.071 g/mol
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  • Amide
  • Amine
  • Drug
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Uremic Toxin
Uremic toxins such as guaniidine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimul...more
Number of Targets: 8
T3D4209Acetamide
60-35-5
C2H5NO
59.067 g/mol
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  • Cigarette Toxin
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
  • Pollutant
Not Available
Number of Targets: 1
T3D3268Acetic acid
64-19-7
C2H3O2
59.045 g/mol
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  • Anti-Bacterial Agent
  • Bacterial Toxin
  • Cigarette Toxin
  • Cosmetic Toxin
  • Drug
  • Food Toxin
  • Fragrance Toxin
  • Household Toxin
  • Indicator and Reagent
  • Industrial/Workplace Toxin
  • Lachrymator
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Pesticide
Acetic acid is toxic due to its corrosive nature. In addition to causing skin burns and irritation to the mucous membranes, ingestion can result in severe damage to th...more
Number of Targets: 4
T3D0049Cobalt
7440-48-4
Co
58.932 g/mol
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  • Cigarette Toxin
  • Cobalt Compound
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Metal
  • Natural Compound
  • Pollutant
Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more
Number of Targets: 38
T3D0053Nickel
7440-02-0
Ni
58.692 g/mol
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  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Metal
  • Natural Compound
  • Nickel Compound
  • Pollutant
Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more
Number of Targets: 73
T3D4666Sodium chloride
7647-14-5
ClNa
58.443 g/mol
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  • Flavouring Agent
  • Food Additive
  • Inorganic Compound
A high salt diet disrupts the natural sodium balance in the body. This causes fluid retention which increases the pressure exerted by the blood against blood vessel wa...more
Number of Targets: 22
T3D3426n-Butane
106-97-8
C4H10
58.122 g/mol
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  • Food Toxin
  • Gasoline Additive/Component
  • Household Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Synthetic Compound
  • Vapour
Butane is a simple asphyxiant and causes toxicity by displacing oxygen. It also affects the central nervous system by enhancing glycine receptors and inhibiting N-meth...more
Number of Targets: 0
T3D3427Isobutane
75-28-5
C4H10
58.122 g/mol
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  • Cosmetic Toxin
  • Food Toxin
  • Gasoline Additive/Component
  • Household Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Synthetic Compound
  • Vapour
Butane is a simple asphyxiant and causes toxicity by displacing oxygen. It also affects the central nervous system by enhancing glycine receptors and inhibiting nicoti...more
Number of Targets: 28
T3D0089Thiocyanate
302-04-5
CNS
58.083 g/mol
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  • Cyanide Compound
  • Food Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Nitrile
  • Organic Compound
  • Plant Toxin
  • Pollutant
Thiocyanate (sulphocyanate or SCN) is believed to be a goitrogenic compound. It is a competitive inhibitor of the human thyroid sodium/iodide symporter NIS. Thus, the ...more
Number of Targets: 8
T3D0184Acetone
67-64-1
C3H6O
58.079 g/mol
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  • Food Toxin
  • Household Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Ketone
  • Lachrymator
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Solvent
Since acetone is highly water soluble, it is readily taken up by the blood and widely distributed to body tissues. Acetone may interfere with the composition of the me...more
Number of Targets: 1
T3D1520Aluminium phosphide
20859-73-8
AlP
57.955 g/mol
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  • Aluminum Compound
  • Inorganic Compound
  • Pesticide
  • Phosphide
  • Synthetic Compound
The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more
Number of Targets: 23
T3D1663Methyl isocyanate
624-83-9
C2H3NO
57.051 g/mol
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  • Cyanide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Pesticide
  • Pollutant
  • Synthetic Compound
Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more
Number of Targets: 40
T3D0037Acrolein
107-02-8
C3H4O
56.063 g/mol
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  • Aldehyde
  • Food Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Lachrymator
  • Metabolite
  • Organic Compound
  • Pesticide
  • Pollutant
  • Synthetic Compound
Acrolein rapidly and irreversibly binds to lysine moieties and sulfhydryl groups found on many cellular molecules forming thiol ethers. By this mechanism acrolein can ...more
Number of Targets: 29
T3D4697Iron
7439-89-6
Fe
55.845 g/mol
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  • Anti-Anemic Agent
  • Drug
  • Food Toxin
  • Household Toxin
  • Inorganic Compound
  • Metabolite
  • Metal
  • Supplement
  • Synthetic Compound
  • Trace Element
Iron is necessary for the production of hemoglobin. Iron-deficiency can lead to decreased production of hemoglobin and a microcytic, hypochromic anemia.
Number of Targets: 0
T3D1708Propionitrile
107-12-0
C3H5N
55.079 g/mol
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  • Cyanide Compound
  • Industrial/Workplace Toxin
  • Nitrile
  • Organic Compound
  • Synthetic Compound
Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more
Number of Targets: 39
T3D0117Manganese
7439-96-5
Mn
54.937 g/mol
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  • Cosmetic Toxin
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Manganese Compound
  • Metabolite
  • Metal
  • Natural Compound
  • Pollutant
Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particu...more
Number of Targets: 10
T3D01561,3-Butadiene
106-99-0
C4H6
54.090 g/mol
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  • Cigarette Toxin
  • Household Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Lachrymator
  • Metabolite
  • Organic Compound
  • Pollutant
  • Synthetic Compound
Certain metabolites of 1,3-butadiene have been shown to bind to DNA and nucleoproteins, forming protein-DNA and DNA-DNA crosslinks. Specifically, 1,2-epoxybutene-3 and...more
Number of Targets: 2
T3D1532Sodium aluminium hydride
13770-96-2
AlH4Na
54.003 g/mol
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  • Aluminum Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Synthetic Compound
The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more
Number of Targets: 3
T3D1688Acrylonitrile
107-13-1
C3H3N
53.063 g/mol
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  • Cigarette Toxin
  • Cyanide Compound
  • Household Toxin
  • Nitrile
  • Organic Compound
  • Pollutant
  • Synthetic Compound
Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more
Number of Targets: 39
T3D0754Cyanogen
460-19-5
C2N2
52.035 g/mol
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  • Cyanide Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Nitrile
  • Organic Compound
  • Synthetic Compound
Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more
Number of Targets: 39
T3D0018Hexavalent chromium
18540-29-9
Cr
51.996 g/mol
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  • Chromium Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Natural Compound
  • Pollutant
Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more
Number of Targets: 5
T3D0077Chromium
7440-47-3
Cr
51.993 g/mol
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  • Chromium Compound
  • Cigarette Toxin
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Metal
  • Natural Compound
  • Pollutant
Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more
Number of Targets: 6
T3D0198Vanadium
7440-62-2
V
50.940 g/mol
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  • Food Toxin
  • Inorganic Compound
  • Metabolite
  • Metal
  • Natural Compound
  • Vanadium Compound
Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impairing the cell's phagocytotic ability and viability. The pentavalent fo...more
Number of Targets: 47
T3D0766Sodium cyanide
143-33-9
CNNa
49.007 g/mol
Thumb
  • Cyanide Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Nitrile
  • Organic Compound
  • Pollutant
  • Synthetic Compound
Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more
Number of Targets: 42
T3D4725Ozone
10028-15-6
O3
47.998 g/mol
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  • Food Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Lachrymator
  • Metabolite
  • Natural Compound
Ozone is a strong oxidant and reacts directly with organic double bonds. When ozone breaks down to dioxygen it gives rise to oxygen free radicals, which are highly rea...more
Number of Targets: 1
Displaying toxin 3476 - 3500 of 3678 in total