Browsing Toxins
Displaying toxin 3651 - 3675 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2492 | Holocyclotoxin 88254-04-0 | Not Available 7834.125 g/mol |  |
| Holocyclotoxin produces paralysis by acting at the neuromuscular junction. (A2834) Number of Targets: 0 |
| T3D2493 | Poneratoxin 137084-94-7 | Not Available 2757.330 g/mol |  |
| Poneratoxin affects voltage-dependent sodium ion channels and is known to block nicotinic synaptic transmission in the insect central nervous system. (L1019) Number of Targets: 14 |
| T3D2494 | omega-Agatoxin 145017-83-0 | Not Available 12807.575 g/mol |  |
| omega-Agatoxins block the calcium channels in the presynaptic terminals of the neuromuscular junction in insects and vertebrates. This reduces calcium influx, resultin...more Number of Targets: 1 |
| T3D2495 | Atracotoxin, omega- (Hadronyche versuta) 193981-10-1 | Not Available 4055.410 g/mol |  |
| omega-Atracotoxins inhibit invertebrate voltage-gated calcium channel currents. (T170, L1812) Number of Targets: 0 |
| T3D2496 | Versutoxin 114264-83-4 | Not Available 4855.645 g/mol |  |
| Versutoxin inhibits both insect and mammalian voltage-gated sodium channels. It binds to site 3 in tetrodotoxin-sensitive sodium channels, which slows their inactivati...more Number of Targets: 14 |
| T3D2497 | Robustoxin 91728-12-0 | Not Available 4856.685 g/mol |  |
| Robustoxin inhibits both insect and mammalian voltage-gated sodium channels. It binds to site 3 in tetrodotoxin-sensitive sodium channels, which slows their inactivati...more Number of Targets: 14 |
| T3D2498 | Grammotoxin 152617-90-8 | Not Available 9600.980 g/mol |  |
| Grammotoxin inhibits P-, Q- and N-type voltage-gated calcium channels in neurons. Binding to the calcium channels modifies their voltage-dependent gating. This makes i...more Number of Targets: 3 |
| T3D2499 | Huwentoxin 526224-73-7 | Not Available 9318.830 g/mol |  |
| Huwentoxin blocks neuromuscular transmission by binding to the nicotinic acetylcholine receptor, which affects the release of neurotransmitters from autonomic nerve en...more Number of Targets: 17 |
| T3D2500 | alpha-Latrotoxin 65988-34-3 | Not Available 156855.500 g/mol |  |
| alpha-Latrotoxin acts presynaptically to release neurotransmitters from sensory and motor neurons, as well as on endocrine cells. alpha-Latrotoxin tetramers can form i...more Number of Targets: 10 |
| T3D2501 | Phrixotoxin 880886-00-0 or 221872-97-5 | Not Available 3555.310 g/mol |  |
| Phrixotoxin blocks A-type potassium channels by altering the gating properties of these channels. (T170) Number of Targets: 2 |
| T3D2502 | Stromatoxin 1262235-00-6 | Not Available 3798.295 g/mol |  |
| Stromatoxin blocks the delayed-rectifier type potassium channels Kv2.1, Kv2.2, Kv2.1/9.3 and the A-type potassium channel Kv4.2, with affinity (IC50) of 12.7 nM, 21.4 ...more Number of Targets: 4 |
| T3D2503 | Phoneutriatoxin Not Available | Not Available 12677.715 g/mol | |
| Phoneutriatoxin acts as an antagonist at certain calcium channels. (T170) Number of Targets: 3 |
| T3D3771 | Restrictocin (Aspergillus restrictus) 1406-72-0 | Not Available 19595.005 g/mol |  |
| Restrictocin is a highly specific ribotoxin that inhibits protein synthesis by cleaving a single phosphodiester bond in the sarcin/ricin loop (SRL) of the 23S−28S rRNA...more Number of Targets: 1 |
| T3D1518 | Aluminium oxynitride 12633-97-5 | (AlN)x·(Al2O3)1-x, 0.30 ≤ x ≤ 0.37 Not Available |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D2505 | Heteropodatoxin 189120-72-7 | Not Available 3917.380 g/mol |  |
| Heteropodatoxin blocks A-type, transient voltage-gated potassium channels by acting as a gating modifier. As a result, a larger depolarization is needed to open the ch...more Number of Targets: 3 |
| T3D2506 | Agitoxin 155646-21-2 | Not Available 4020.835 g/mol |  |
| Agitoxin binds to and blocks the Shaker potassium channel in Drosophila as well as to its mammalian homologue. (A157) Number of Targets: 8 |
| T3D3773 | alpha-Sarcin (Aspergillus giganteus) 86243-64-3 | Not Available 19724.200 g/mol |  |
| alpha-Sarcin is a highly specific ribotoxin that inhibits protein synthesis by cleaving a single phosphodiester bond in the sarcin/ricin loop (SRL) of the 23S−28S rRNA...more Number of Targets: 1 |
| T3D2507 | Charybdotoxin 95751-30-7 | Not Available 6673.890 g/mol |  |
| Charybdotoxin is a neurotoxin that blocks calcium-activated and voltage gated potassium channels by binding to one of four independent, overlapping binding sites. This...more Number of Targets: 10 |
| T3D2508 | Chlorotoxin 163515-35-3 | Not Available 4004.725 g/mol |  |
| Chlorotoxin blocks small conductance chloride channels. (L1043) Number of Targets: 15 |
| T3D2509 | Cobatoxin 211688-17-4 | Not Available 7131.365 g/mol |  |
| Cobatoxin blocks calcium-activated and voltage-gated potassium channels. (L1045) Number of Targets: 7 |
| T3D2510 | alpha-Cobratoxin 769933-79-1 | Not Available 7830.960 g/mol |  |
| alpha-Cobratoxin is a muscle-type nicotinic acetylcholine receptor (nAChR) antagonist. It causes paralysis by preventing the binding of acetylcholine to the nAChR, as ...more Number of Targets: 6 |
| T3D2511 | kappa-Hefutoxin 478621-50-0 | Not Available 2659.865 g/mol |  |
| kappa-Hefutoxin blocks voltage-gated potassium channels and also slows down their activation kinetics. (L1048) Number of Targets: 2 |
| T3D2513 | Imperatoxin-A 172451-37-5 | Not Available 3764.370 g/mol |  |
| Imperatoxin-A is an activator which enhances the influx of Ca2+ from the sarcoplasmatic reticulum into the cell. Imperatoxin-A acts on the Ryanodine receptors (RyR), w...more Number of Targets: 3 |
| T3D2514 | Imperatoxin-1 Not Available | Not Available 18663.670 g/mol | |
| Imperatoxin-I is an inhibitor which decreases the influx of Ca2+ from the sarcoplasmatic reticulum into the cell. Imperatoxin-I acts on the Ryanodine receptors (RyR), ...more Number of Targets: 3 |
| T3D2515 | Kaliotoxin 145199-73-1 | Not Available 6461.905 g/mol |  |
| Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. It binds to the extracellular surface and blocks the channel, affectin...more Number of Targets: 6 |