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Displaying toxin 51 - 75 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D3588Amanullin
21803-57-6
C39H54N10O12S
886.971 g/mol
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  • Amide
  • Amine
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in the synthesis of messenger RNA (mRNA), microRNA, and small nuclear RNA...more
Number of Targets: 14
T3D0328Lead molybdenum chromate
12709-98-7
Cr2Mo2O11Pb2
886.300 g/mol
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  • Chromium Compound
  • Inorganic Compound
  • Lead Compound
  • Pollutant
  • Synthetic Compound
Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more
Number of Targets: 34
T3D1043Emamectin B1a
121124-29-6
C49H75NO13
886.119 g/mol
Thumb
  • Amine
  • Avermectin
  • Bacterial Toxin
  • Ester
  • Ether
  • Lachrymator
  • Natural Compound
  • Organic Compound
  • Pesticide
It has low solubility in water and extensive non-specific binding. It opens GABA-insensitive chloride channels, reducing membrane resistance and increasing conductance...more
Number of Targets: 11
T3D2645Brevetoxin
98112-41-5
C49H68O14
881.056 g/mol
Thumb
  • Aldehyde
  • Animal Toxin
  • Ester
  • Ether
  • Marine Toxin
  • Natural Compound
  • Organic Compound
Brevetoxins are neurotoxins that bind to voltage-gated sodium channels in nerve cells, leading to disruption of normal neurological processes. (L1112)
Number of Targets: 14
T3D2044Nonabromobiphenyl Ether
63936-56-1
C12HBr9O
880.272 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Bromide Compound
  • Ether
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
Like other halogenated aromatic hydrocarbons, polybrominated diphenyl ethers bind to the cellular aryl hydrocarbon receptor (AhR), which regulates the synthesis of a v...more
Number of Targets: 6
T3D4914Fd&c red no. 3
16423-68-0
C20H6I4Na2O5
879.856 g/mol
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  • Ester
  • Food Additive
  • Food Toxin
  • Household Toxin
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Not Available
Number of Targets: 2
T3D1556Aluminium octadecanoate
637-12-7
C54H105AlO6
877.389 g/mol
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  • Aluminum Compound
  • Food Toxin
  • Household Toxin
  • Metabolite
  • Organic Compound
  • Organometallic
  • Synthetic Compound
The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more
Number of Targets: 3
T3D3018Rifapentine
61379-65-5
C47H64N4O12
877.031 g/mol
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  • Amide
  • Amine
  • Antibiotic, Antitubercular
  • Antimycobacterial
  • Drug
  • Ester
  • Ether
  • Hydrazine
  • Leprostatic Agent
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Rifapentine has shown higher bacteriostatic and bactericidal activities especially against intracellular bacteria growing in human monocyte-derived macrophages. Rifape...more
Number of Targets: 0
T3D499522,23-dihydroavermectin b1a
71827-03-7
C48H74O14
875.093 g/mol
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  • Antiparasitic Agent
  • Avermectin
  • Drug
  • Lachrymator
  • Metabolite
  • Synthetic Compound
Ivermectin binds selectively and with high affinity to glutamate-gated chloride ion channels in invertebrate muscle and nerve cells of the microfilaria. This binding c...more
Number of Targets: 14
T3D1041Avermectin B1a
65195-55-3
C48H72O14
873.077 g/mol
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  • Avermectin
  • Bacterial Toxin
  • Ester
  • Ether
  • Household Toxin
  • Lachrymator
  • Natural Compound
  • Organic Compound
  • Pesticide
It has low solubility in water and extensive non-specific binding. It opens GABA-insensitive chloride channels, reducing membrane resistance and increasing conductance...more
Number of Targets: 11
T3D1044Emamectin B1b
121424-52-0
C48H73NO13
872.092 g/mol
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  • Amine
  • Avermectin
  • Bacterial Toxin
  • Ester
  • Ether
  • Lachrymator
  • Natural Compound
  • Organic Compound
  • Pesticide
It has low solubility in water and extensive non-specific binding. It opens GABA-insensitive chloride channels, reducing membrane resistance and increasing conductance...more
Number of Targets: 11
T3D1560Trieicosylaluminum
1529-57-3
C60H123Al
871.600 g/mol
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  • Aluminum Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organometallic
  • Synthetic Compound
The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more
Number of Targets: 3
T3D1548Aluminum oleate
688-37-9
C54H99AlO6
871.342 g/mol
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  • Aluminum Compound
  • Food Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organometallic
  • Synthetic Compound
The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more
Number of Targets: 3
T3D3592Proamanullin
54532-46-6
C39H54N10O11S
870.971 g/mol
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  • Amide
  • Amine
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in the synthesis of messenger RNA (mRNA), microRNA, and small nuclear RNA...more
Number of Targets: 14
T3D4042alpha-Solanine
20562-02-1
C45H73NO15
868.059 g/mol
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  • Amine
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Solanum glycoalkaloids can inhibit cholinesterase, disrupt cell membranes, and be teratogenic (cause birth defects). One study suggests that the toxic mechanism of sol...more
Number of Targets: 0
T3D19922,2',3,3',4,4',5,5',6-Nonabromobiphenyl
69278-62-2
C12HBr9
864.272 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Bromide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more
Number of Targets: 1
T3D19362,2',3,3',4,5,5',6,6'-Nonabromobiphenyl
119264-63-0
C12HBr9
864.272 g/mol
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  • Aromatic Hydrocarbon
  • Bromide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more
Number of Targets: 1
T3D19352,2',3,3',4,4',5,6,6'-Nonabromobiphenyl
60586-57-4
C12HBr9
864.272 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Bromide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more
Number of Targets: 1
T3D2473Phallisacin
58286-46-7
C37H50N8O14S
862.903 g/mol
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  • Amide
  • Amine
  • Ether
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
  • Phallotoxin
Phallotoxins bind actin, preventing its depolymerization and poisoning the cell. They bind specifically at the interface between F-actin subunits, locking adjacent sub...more
Number of Targets: 6
T3D499622,23-dihydroavermectin b1b
70209-81-3
C47H72O14
861.066 g/mol
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  • Antiparasitic Agent
  • Avermectin
  • Drug
  • Lachrymator
  • Metabolite
  • Synthetic Compound
Ivermectin binds selectively and with high affinity to glutamate-gated chloride ion channels in invertebrate muscle and nerve cells of the microfilaria. This binding c...more
Number of Targets: 14
T3D1684Ferric hexacyanoferrate
14038-43-8
C18Fe7N18
859.228 g/mol
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  • Cyanide Compound
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Synthetic Compound
Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more
Number of Targets: 39
T3D1042Avermectin B1b
65195-56-4
C47H70O14
859.050 g/mol
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  • Avermectin
  • Bacterial Toxin
  • Ester
  • Ether
  • Lachrymator
  • Natural Compound
  • Organic Compound
  • Pesticide
It has low solubility in water and extensive non-specific binding. It opens GABA-insensitive chloride channels, reducing membrane resistance and increasing conductance...more
Number of Targets: 11
T3D4019Paclitaxel
33069-62-4
C47H51NO14
853.906 g/mol
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  • Amine
  • Antineoplastic Agent, Phytogenic
  • Drug
  • Ester
  • Ether
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
  • Tubulin Modulator
Paclitaxel interferes with the normal function of microtubule growth. Whereas drugs like colchicine cause the depolymerization of microtubules in vivo, paclitaxel arre...more
Number of Targets: 6
T3D4050alpha-Chaconine
20562-03-2
C45H73NO14
852.059 g/mol
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  • Amine
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Alpha-Chaconine has inhibitory effect on lung adenocarcinoma cell metastasis in vitro. Alpha-chaconine could inhibit phosphorylation of c-Jun N-terminal kinase (JNK) a...more
Number of Targets: 0
T3D2838Rifabutin
72559-06-9
C46H62N4O11
847.005 g/mol
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  • Amide
  • Amine
  • Anti-Bacterial Agent
  • Antibiotic, Antitubercular
  • Drug
  • Ester
  • Ether
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Rifabutin acts via the inhibition of DNA-dependent RNA polymerase in gram-positive and some gram-negative bacteria, leading to a suppression of RNA synthesis and cell ...more
Number of Targets: 2
Displaying toxin 51 - 75 of 3678 in total