Tmic
You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on Toxin, Toxin Target Database.
Displaying toxins 76 - 100 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D0753Copper(I) cyanide
544-92-3
CCuN
89.563 g/mol
Thumb
  • Copper Compound
  • Cyanide Compound
  • Inorganic Compound
  • Nitrile
  • Organic Compound
  • Pesticide
  • Pollutant
  • Synthetic Compound
Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more
Number of Targets: 47
T3D4841Dimethylethanolamine
108-01-0
C4H11NO
89.136 g/mol
Thumb
  • Amine
  • Food Additive
  • Food Toxin
  • Household Toxin
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Not Available
Number of Targets: 1
T3D4320L-Alanine
56-41-7
C3H7NO2
89.093 g/mol
Thumb
  • Amine
  • Animal Toxin
  • Dietary Supplement
  • Drug
  • Food Toxin
  • Household Toxin
  • Metabolite
  • Micronutrient
  • Natural Compound
  • Non-Essential Amino Acid
  • Nutraceutical
  • Organic Compound
  • Supplement
L-Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar...more
Number of Targets: 13
T3D4583Ethyl carbamate
51-79-6
C3H7NO2
89.093 g/mol
Thumb
  • Amine
  • Anesthetic, Intravenous
  • Antineoplastic Agent
  • Carcinogen
  • Ester
  • Ether
  • Food Toxin
  • Lachrymator
  • Metabolite
  • Organic Compound
  • Pollutant
  • Synthetic Compound
Ethyl carbamate is genotoxic and a potent carcinogen. It exerts its effects through the formation of DNA adducts (via its vinyl carbamate epoxide metabolite) that ind...more
Number of Targets: 3
T3D4346Beta-Alanine
107-95-9
C3H7NO2
89.093 g/mol
Thumb
  • Amine
  • Animal Toxin
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
Not Available
Number of Targets: 3
T3D4458Sarcosine
107-97-1
C3H7NO2
89.093 g/mol
Thumb
  • Amine
  • Animal Toxin
  • Food Toxin
  • Industrial/Workplace Toxin
  • Lachrymator
  • Metabolite
  • Natural Compound
  • Organic Compound
Sarcosine is an oncometabolite. Sarcosine appears to upregulate the expression of the potent oncoprotein called human epidermal growth factor receptor 2 (HER2/neu) in ...more
Number of Targets: 2
T3D3589Amanullinic acid
54532-45-5
C39H53N9O13S
887.956 g/mol
Thumb
  • Amide
  • Amine
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in the synthesis of messenger RNA (mRNA), microRNA, and small nuclear RNA...more
Number of Targets: 14
T3D3588Amanullin
21803-57-6
C39H54N10O12S
886.971 g/mol
Thumb
  • Amide
  • Amine
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in the synthesis of messenger RNA (mRNA), microRNA, and small nuclear RNA...more
Number of Targets: 14
T3D0328Lead molybdenum chromate
12709-98-7
Cr2Mo2O11Pb2
886.300 g/mol
Thumb
  • Chromium Compound
  • Inorganic Compound
  • Lead Compound
  • Pollutant
  • Synthetic Compound
Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more
Number of Targets: 34
T3D1043Emamectin B1a
121124-29-6
C49H75NO13
886.119 g/mol
Thumb
  • Amine
  • Avermectin
  • Bacterial Toxin
  • Ester
  • Ether
  • Lachrymator
  • Natural Compound
  • Organic Compound
  • Pesticide
It has low solubility in water and extensive non-specific binding. It opens GABA-insensitive chloride channels, reducing membrane resistance and increasing conductance...more
Number of Targets: 11
T3D2645Brevetoxin
98112-41-5
C49H68O14
881.056 g/mol
Thumb
  • Aldehyde
  • Animal Toxin
  • Ester
  • Ether
  • Marine Toxin
  • Natural Compound
  • Organic Compound
Brevetoxins are neurotoxins that bind to voltage-gated sodium channels in nerve cells, leading to disruption of normal neurological processes. (L1112)
Number of Targets: 14
T3D2044Nonabromobiphenyl Ether
63936-56-1
C12HBr9O
880.272 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Bromide Compound
  • Ether
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
Like other halogenated aromatic hydrocarbons, polybrominated diphenyl ethers bind to the cellular aryl hydrocarbon receptor (AhR), which regulates the synthesis of a v...more
Number of Targets: 6
T3D4169Putrescine
110-60-1
C4H12N2
88.152 g/mol
Thumb
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Uremic Toxin
Uremic toxins such as putrescine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimul...more
Number of Targets: 7
T3D4592Butyric acid
107-92-6
C4H8O2
88.105 g/mol
Thumb
  • Animal Toxin
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
Butyric acid is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholines...more
Number of Targets: 10
T3D02101,4-Dioxane
123-91-1
C4H8O2
88.105 g/mol
Thumb
  • Cosmetic Toxin
  • Ether
  • Household Toxin
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Pollutant
  • Solvent
  • Synthetic Compound
Though the mechanism of toxicity of 1,4-dioxane has not yet been elucidated, it is known that its carcinogenic effects are caused by a non-genotoxic mechanism that is ...more
Number of Targets: 4
T3D1525Methylaluminoxane
120144-90-3
C3H9AlO
88.085 g/mol
Thumb
  • Aluminum Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organometallic
  • Synthetic Compound
The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more
Number of Targets: 3
T3D4325Pyruvic acid
127-17-3
C3H4O3
88.062 g/mol
Thumb
  • Animal Toxin
  • Dietary Supplement
  • Drug
  • Food Toxin
  • Metabolite
  • Micronutrient
  • Natural Compound
  • Nutraceutical
  • Organic Compound
  • Supplement
Pyruvate serves as a biological fuel by being converted to acetyl coenzyme A, which enters the tricarboxylic acid or Krebs cycle where it is metabolized to produce ATP...more
Number of Targets: 16
T3D4914Fd&c red no. 3
16423-68-0
C20H6I4Na2O5
879.856 g/mol
Thumb
  • Ester
  • Food Additive
  • Food Toxin
  • Household Toxin
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Not Available
Number of Targets: 2
T3D1556Aluminium octadecanoate
637-12-7
C54H105AlO6
877.389 g/mol
Thumb
  • Aluminum Compound
  • Food Toxin
  • Household Toxin
  • Metabolite
  • Organic Compound
  • Organometallic
  • Synthetic Compound
The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more
Number of Targets: 3
T3D3018Rifapentine
61379-65-5
C47H64N4O12
877.031 g/mol
Thumb
  • Amide
  • Amine
  • Antibiotic, Antitubercular
  • Antimycobacterial
  • Drug
  • Ester
  • Ether
  • Hydrazine
  • Leprostatic Agent
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Rifapentine has shown higher bacteriostatic and bactericidal activities especially against intracellular bacteria growing in human monocyte-derived macrophages. Rifape...more
Number of Targets: 0
T3D499522,23-dihydroavermectin b1a
71827-03-7
C48H74O14
875.093 g/mol
Thumb
  • Antiparasitic Agent
  • Avermectin
  • Drug
  • Lachrymator
  • Metabolite
  • Synthetic Compound
Ivermectin binds selectively and with high affinity to glutamate-gated chloride ion channels in invertebrate muscle and nerve cells of the microfilaria. This binding c...more
Number of Targets: 14
T3D1041Avermectin B1a
65195-55-3
C48H72O14
873.077 g/mol
Thumb
  • Avermectin
  • Bacterial Toxin
  • Ester
  • Ether
  • Household Toxin
  • Lachrymator
  • Natural Compound
  • Organic Compound
  • Pesticide
It has low solubility in water and extensive non-specific binding. It opens GABA-insensitive chloride channels, reducing membrane resistance and increasing conductance...more
Number of Targets: 11
T3D1044Emamectin B1b
121424-52-0
C48H73NO13
872.092 g/mol
Thumb
  • Amine
  • Avermectin
  • Bacterial Toxin
  • Ester
  • Ether
  • Lachrymator
  • Natural Compound
  • Organic Compound
  • Pesticide
It has low solubility in water and extensive non-specific binding. It opens GABA-insensitive chloride channels, reducing membrane resistance and increasing conductance...more
Number of Targets: 11
T3D1560Trieicosylaluminum
1529-57-3
C60H123Al
871.600 g/mol
Thumb
  • Aluminum Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organometallic
  • Synthetic Compound
The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more
Number of Targets: 3
T3D1548Aluminum oleate
688-37-9
C54H99AlO6
871.342 g/mol
Thumb
  • Aluminum Compound
  • Food Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organometallic
  • Synthetic Compound
The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more
Number of Targets: 3
Displaying toxins 76 - 100 of 3678 in total