Tmic
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Displaying toxins 201 - 225 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D0234Arsine
7784-42-1
AsH3
77.945 g/mol
Thumb
  • Arsenic Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Pollutant
  • Synthetic Compound
Arsine enters the bloodstream and crosses the alveolo-capillary membrane into red blood cells. Here it preferentially binds to hemoglobin and is oxidized to an arsenic...more
Number of Targets: 10
T3D2578Fluoroacetamide
640-19-7
C2H4FNO
77.058 g/mol
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  • Amide
  • Amine
  • Organic Compound
  • Organofluoride
  • Pesticide
  • Synthetic Compound
Fluoroacetate produces its toxin action by inhibiting the citric acid cycle. The fluorine substituted acetate becomes incorporated, as a normal acetate, into fluoroace...more
Number of Targets: 0
T3D4021Digitoxin
71-63-6
C41H64O13
764.939 g/mol
Thumb
  • Anti-Arrhythmia Agent
  • Cardiotonic Agent
  • Drug
  • Enzyme Inhibitor
  • Ester
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Digitoxin inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations. Increased intracellular concentrations o...more
Number of Targets: 2
T3D4916Fast green FCF
2353-45-9
C37H36N2O10S3
764.884 g/mol
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  • Amine
  • Dye
  • Ester
  • Food Additive
  • Food Toxin
  • Household Toxin
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Not Available
Number of Targets: 5
T3D1349Mercuric oleate
1191-80-6
C36H66HgO4
763.500 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Mercury Compound
  • Organic Compound
  • Organometallic
  • Pollutant
  • Synthetic Compound
High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more
Number of Targets: 50
T3D0696Nickel oxide
1313-99-1
H2NiO
76.709 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Natural Compound
  • Nickel Compound
  • Pollutant
Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more
Number of Targets: 68
T3D0176Carbon disulfide
75-15-0
CS2
76.141 g/mol
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  • Food Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Pollutant
  • Solvent
Carbon disulfide is a potent nerve toxin and also affect liver enzymes, particularly those related to lipid metabolism. The increases in serum cholesterol that are som...more
Number of Targets: 3
T3D4891Thiourea
62-56-6
CH4N2S
76.121 g/mol
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  • Amine
  • Food Toxin
  • Household Toxin
  • Indicator and Reagent
  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Not Available
Number of Targets: 1
T3D0760Ammonium thiocyanate
1762-95-4
CH4N2S
76.121 g/mol
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  • Cyanide Compound
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Nitrile
  • Organic Compound
  • Pollutant
  • Synthetic Compound
Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more
Number of Targets: 42
T3D3881Methyl cellusolve
9004-74-4
C3H8O2
76.094 g/mol
Thumb
  • Dye
  • Ether
  • Industrial/Workplace Toxin
  • Organic Compound
  • Solvent
  • Synthetic Compound
Not Available
Number of Targets: 7
T3D4778Propylene glycol
57-55-6
C3H8O2
76.094 g/mol
Thumb
  • Food Additive
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Solvent
  • Synthetic Compound
Not Available
Number of Targets: 2
T3D4767Hydroxyurea
127-07-1
CH4N2O2
76.055 g/mol
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  • Amine
  • Antineoplastic Agent
  • Antisickling Agent
  • Drug
  • Enzyme Inhibitor
  • Metabolite
  • Nucleic Acid Synthesis Inhibitor
  • Organic Compound
  • Synthetic Compound
Hydroxyurea is converted to a free radical nitroxide (NO) in vivo, and transported by diffusion into cells where it quenches the tyrosyl free radical at the active sit...more
Number of Targets: 2
T3D3660Glycolic acid
79-14-1
C2H4O3
76.051 g/mol
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  • Cosmetic Toxin
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Keratolytic Agent
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Glycolic acid's toxicity is due to its metabolism to oxalic acid. Glycolic and oxalic acid, along with excess lactic acid, are responsible for the anion gap metabolic ...more
Number of Targets: 1
T3D1137Mangafodipir
140678-14-4
C22H27MnN4Na3O14P2
757.323 g/mol
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  • Amine
  • Industrial/Workplace Toxin
  • Manganese Compound
  • Organic Compound
  • Organometallic
  • Pollutant
  • Synthetic Compound
Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particu...more
Number of Targets: 5
T3D2468Prophalloin
67739-84-8
C35H48N8O9S
756.869 g/mol
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  • Amide
  • Amine
  • Ether
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
  • Phallotoxin
Phallotoxins bind actin, preventing its depolymerization and poisoning the cell. They bind specifically at the interface between F-actin subunits, locking adjacent sub...more
Number of Targets: 6
T3D2479Vindesine
53643-48-4
C43H55N5O7
753.926 g/mol
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  • Amide
  • Amine
  • Antineoplastic Agent
  • Antineoplastic Agent, Phytogenic
  • Drug
  • Ester
  • Ether
  • Metabolite
  • Organic Compound
  • Synthetic Compound
  • Tubulin Modulator
Vindesine acts by causing the arrest of cells in metaphase mitosis through its inhibition tubulin mitotic funcitoning. The drug is cell-cycle specific for the S phase.
Number of Targets: 1
T3D1361Merbromin
129-16-8
C20H8Br2HgNa2O6
750.650 g/mol
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  • Aromatic Hydrocarbon
  • Bromide Compound
  • Ester
  • Industrial/Workplace Toxin
  • Mercury Compound
  • Organic Compound
  • Organobromide
  • Organometallic
  • Pollutant
  • Synthetic Compound
High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more
Number of Targets: 56
T3D4164Trimethylamine N-oxide
1184-78-7
C3H9NO
75.110 g/mol
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  • Food Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Uremic Toxin
Uremic toxins such as TMAO are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimulate th...more
Number of Targets: 3
T3D4318Glycine
56-40-6
C2H5NO2
75.067 g/mol
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  • Amine
  • Animal Toxin
  • Dietary Supplement
  • Drug
  • Food Toxin
  • Glycine Agent
  • Household Toxin
  • Metabolite
  • Micronutrient
  • Natural Compound
  • Non-Essential Amino Acid
  • Nutraceutical
  • Organic Compound
  • Supplement
In the CNS, there exist strychnine-sensitive glycine binding sites as well as strychnine-insensitive glycine binding sites. The strychnine-insensitive glycine-binding ...more
Number of Targets: 31
T3D1280Monomethyltin tris(isooctyl mercaptoacetate)
54849-38-6
C31H60O6S3Sn
743.710 g/mol
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  • Ester
  • Ether
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organometallic
  • Synthetic Compound
  • Tin Compound
Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more
Number of Targets: 12
T3D0666Cobalt(II) oxide
1307-96-6
CoO
74.933 g/mol
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  • Cobalt Compound
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Pollutant
  • Synthetic Compound
Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more
Number of Targets: 35
T3D0001Arsenic
7440-38-2
As
74.920 g/mol
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  • Arsenic Compound
  • Cigarette Toxin
  • Food Toxin
  • Household Toxin
  • Inorganic Compound
  • Metabolite
  • Metal
  • Metalloid
  • Natural Compound
  • Pesticide
  • Pollutant
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more
Number of Targets: 46
T3D1543Titanium aluminide
12003-96-2
AlTi
74.849 g/mol
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  • Aluminum Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Synthetic Compound
The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more
Number of Targets: 3
T3D1417Nickel trioxide
1314-06-3
NiO
74.693 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Nickel Compound
  • Pollutant
  • Synthetic Compound
Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more
Number of Targets: 68
T3D4731Potassium Chloride
7447-40-7
ClK
74.551 g/mol
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  • Drug
  • Food Toxin
  • Household Toxin
  • Inorganic Compound
  • Natural Compound
Supplemental potassium in the form of high potassium food or potassium chloride may be able to restore normal potassium levels.
Number of Targets: 6
Displaying toxins 201 - 225 of 3678 in total