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Displaying toxin 1 - 25 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D0793Tremolite Asbestos
77536-68-6
(Na, K)0-1Ca2Mg5Si8O22(OH)2
Not Available
T3d0793
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Mineral
  • Natural Compound
  • Pollutant
When asbestos fibers are inhaled, many are deposited on the epithelial surface of the respiratory tree. Fibers that are retained in the lung or mesothelium for long pe...more
Number of Targets: 1
T3D0794Actinolite Asbestos
77536-66-4
(Na, K)0-1Ca2(Mg, Fe)5Si8O22(OH)2
Not Available
T3d0794
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Mineral
  • Natural Compound
  • Pollutant
When asbestos fibers are inhaled, many are deposited on the epithelial surface of the respiratory tree. Fibers that are retained in the lung or mesothelium for long pe...more
Number of Targets: 1
T3D0795Anthophyllite Asbestos
77536-67-5
(Na, K)0-1Mg2(Mg, Fe)5Si8O22(OH)2, Mg/(Mg + Fe) > 0.6
Not Available
T3d0795
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Mineral
  • Natural Compound
  • Pollutant
When asbestos fibers are inhaled, many are deposited on the epithelial surface of the respiratory tree. Fibers that are retained in the lung or mesothelium for long pe...more
Number of Targets: 1
T3D1374Cadmium(I) tetrachloroaluminate
79110-87-5
Cd2Al2Cl8
562.412 g/mol
T3d1374
  • Aluminum Compound
  • Cadmium Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Pollutant
  • Synthetic Compound
Cadmium initially binds to metallothionein and is transported to the kidney. Toxic effects are observed once the concentration of cadmium exceeds that of available met...more
Number of Targets: 21
T3D1518Aluminium oxynitride
12633-97-5
(AlN)x·(Al2O3)1-x, 0.30 ≤ x ≤ 0.37
Not Available
T3d1518
  • Aluminum Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Synthetic Compound
The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more
Number of Targets: 3
T3D1567Diaspore
14457-84-2
AlO(OH)
59.988 g/mol
T3d1567
  • Aluminum Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Natural Compound
The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more
Number of Targets: 3
T3D2477Insulin
11061-68-0
Not Available
11980.795 g/mol
T3d2477
  • Amide
  • Amine
  • Animal Toxin
  • Antidiabetic Agent
  • Hormone
  • Natural Compound
  • Organic Compound
  • Protein
Insulin has a direct inhibitory effect on the lipase concerned with the mobilization of fattty acids. Insulin binds to a receptor on the surface of the target cell and...more
Number of Targets: 56
T3D2481Ricin
9009-86-3
Not Available
64089.975 g/mol
T3d2481
  • Amide
  • Amine
  • Natural Compound
  • Organic Compound
  • Plant Toxin
  • Protein
Pure ricin consists of a neutral A chain and an acidic B chain connected by S--S bonds. The A chain is capable of inhibiting protein synthesis which results in its tox...more
Number of Targets: 1
T3D2490alpha-Pompilidotoxin
202075-91-0
Not Available
1530.850 g/mol
T3d2490
  • Amide
  • Amine
  • Animal Toxin
  • Insect Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Pompilidotoxin slows down inactivation of neuronal, but not heart sodium channels, potentiating synaptic transmission. This is believed to be done by binding to the n...more
Number of Targets: 10
T3D2491beta-Pompilidotoxin
216064-36-7
Not Available
1558.860 g/mol
T3d2491
  • Amide
  • Amine
  • Animal Toxin
  • Insect Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Pompilidotoxin slows down inactivation of neuronal, but not heart sodium channels, potentiating synaptic transmission. This is believed to be done by binding to the n...more
Number of Targets: 10
T3D2492Holocyclotoxin
88254-04-0
Not Available
7834.125 g/mol
T3d2492
  • Amide
  • Amine
  • Animal Toxin
  • Insect Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Holocyclotoxin produces paralysis by acting at the neuromuscular junction. (A2834)
Number of Targets: 0
T3D2493Poneratoxin
137084-94-7
Not Available
2757.330 g/mol
T3d2493
  • Amide
  • Amine
  • Animal Toxin
  • Insect Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Poneratoxin affects voltage-dependent sodium ion channels and is known to block nicotinic synaptic transmission in the insect central nervous system. (L1019)
Number of Targets: 14
T3D2494omega-Agatoxin
145017-83-0
Not Available
12807.575 g/mol
T3d2494
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
omega-Agatoxins block the calcium channels in the presynaptic terminals of the neuromuscular junction in insects and vertebrates. This reduces calcium influx, resultin...more
Number of Targets: 1
T3D2495Atracotoxin, omega- (Hadronyche versuta)
193981-10-1
Not Available
4055.410 g/mol
T3d2495
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
omega-Atracotoxins inhibit invertebrate voltage-gated calcium channel currents. (T170, L1812)
Number of Targets: 0
T3D2496Versutoxin
114264-83-4
Not Available
4855.645 g/mol
T3d2496
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Versutoxin inhibits both insect and mammalian voltage-gated sodium channels. It binds to site 3 in tetrodotoxin-sensitive sodium channels, which slows their inactivati...more
Number of Targets: 14
T3D2497Robustoxin
91728-12-0
Not Available
4856.685 g/mol
T3d2497
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Robustoxin inhibits both insect and mammalian voltage-gated sodium channels. It binds to site 3 in tetrodotoxin-sensitive sodium channels, which slows their inactivati...more
Number of Targets: 14
T3D2498Grammotoxin
152617-90-8
Not Available
9600.980 g/mol
T3d2498
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Grammotoxin inhibits P-, Q- and N-type voltage-gated calcium channels in neurons. Binding to the calcium channels modifies their voltage-dependent gating. This makes i...more
Number of Targets: 3
T3D2499Huwentoxin
526224-73-7
Not Available
9318.830 g/mol
T3d2499
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Huwentoxin blocks neuromuscular transmission by binding to the nicotinic acetylcholine receptor, which affects the release of neurotransmitters from autonomic nerve en...more
Number of Targets: 17
T3D2500alpha-Latrotoxin
65988-34-3
Not Available
156855.500 g/mol
T3d2500
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
alpha-Latrotoxin acts presynaptically to release neurotransmitters from sensory and motor neurons, as well as on endocrine cells. alpha-Latrotoxin tetramers can form i...more
Number of Targets: 10
T3D2501Phrixotoxin
880886-00-0 or 221872-97-5
Not Available
3555.310 g/mol
T3d2501
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Phrixotoxin blocks A-type potassium channels by altering the gating properties of these channels. (T170)
Number of Targets: 2
T3D2502Stromatoxin
1262235-00-6
Not Available
3798.295 g/mol
No structure small
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Stromatoxin blocks the delayed-rectifier type potassium channels Kv2.1, Kv2.2, Kv2.1/9.3 and the A-type potassium channel Kv4.2, with affinity (IC50) of 12.7 nM, 21.4 ...more
Number of Targets: 4
T3D2503Phoneutriatoxin
Not Available
Not Available
12677.715 g/mol
No structure small
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Phoneutriatoxin acts as an antagonist at certain calcium channels. (T170)
Number of Targets: 3
T3D2505Heteropodatoxin
189120-72-7
Not Available
3917.380 g/mol
T3d2505
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Heteropodatoxin blocks A-type, transient voltage-gated potassium channels by acting as a gating modifier. As a result, a larger depolarization is needed to open the ch...more
Number of Targets: 3
T3D2506Agitoxin
155646-21-2
Not Available
4020.835 g/mol
T3d2506
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Scorpion Toxin
Agitoxin binds to and blocks the Shaker potassium channel in Drosophila as well as to its mammalian homologue. (A157)
Number of Targets: 8
T3D2507Charybdotoxin
95751-30-7
Not Available
6673.890 g/mol
T3d2507
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Scorpion Toxin
Charybdotoxin is a neurotoxin that blocks calcium-activated and voltage gated potassium channels by binding to one of four independent, overlapping binding sites. This...more
Number of Targets: 10
Displaying toxin 1 - 25 of 3678 in total