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Browsing Toxins
Displaying toxin 3251 - 3275 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3681 | Cytochalasin J 56144-22-0 | C28H35NO5 465.581 g/mol |  |
| Cytochalasins are known to bind to the barbed, fast growing plus ends of microfilaments, which then blocks both the assembly and disassembly of individual actin monome...more Number of Targets: 6 |
| T3D2836 | Cisapride 81098-60-4 | C23H29ClFN3O4 465.945 g/mol |  |
| Cisapride acts through the stimulation of the serotonin 5-HT4 receptors which increases acetylcholine release in the enteric nervous system (specifically the myenteric...more Number of Targets: 11 |
| T3D1869 | Dichlorotribenzylantimony 19493-17-5 | C21H21Cl2Sb 466.060 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D1835 | Indium(III) selenide 12056-07-4 | In2Se3 466.520 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 0 |
| T3D3664 | T2 Toxin 21259-20-1 | C24H34O9 466.521 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 6 |
| T3D1320 | Iron cacodylate 5968-84-3 | C6H18As3FeO6 466.813 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D1416 | Nickel bis(dibutyldithiocarbamate) 13927-77-0 | C18H36N2NiS4 467.445 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 68 |
| T3D3682 | Dihydrocytochalasin B 39156-67-7 | C28H37NO5 467.597 g/mol |  |
| Cytochalasins are known to bind to the barbed, fast growing plus ends of microfilaments, which then blocks both the assembly and disassembly of individual actin monome...more Number of Targets: 6 |
| T3D2932 | Buprenorphine 52485-79-7 | C29H41NO4 467.640 g/mol |  |
| Buprenorphine's analgesic effect is due to partial agonist activity at mu-opioid receptors. Buprenorphine is also a kappa-opioid receptor antagonist. The partial agoni...more Number of Targets: 4 |
| T3D4430 | Deoxyuridine triphosphate 1173-82-6 | C9H15N2O14P3 468.142 g/mol |  |
| Deoxyuridine triphosphate (dUTP) can be misincorporated into DNA and cause DNA damage. The extent of DNA damage caused by dUTP is dependent on the levels of the pyroph...more Number of Targets: 3 |
| T3D3902 | Primisulfuron-methyl 86209-51-0 | C15H12F4N4O7S 468.337 g/mol |  |
| Not Available Number of Targets: 7 |
| T3D0288 | Copper arsenate 10103-61-4 | As2Cu3O8 468.476 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 49 |
| T3D1921 | 2,3,4,5-Tetrabromobiphenyl 115245-09-5 | C12H6Br4 469.792 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1922 | 2,3,4,6-Tetrabromobiphenyl 115245-10-8 | C12H6Br4 469.792 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1942 | 3,3',5,5'-Tetrabromobiphenyl 16400-50-3 | C12H6Br4 469.792 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1953 | Tetrabromobiphenyl 40088-45-7 | C12H6Br4 469.792 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1967 | 2,2',5,5'-Tetrabromobiphenyl 59080-37-4 | C12H6Br4 469.792 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1968 | 2,3',4',5-Tetrabromobiphenyl 59080-38-5 | C12H6Br4 469.792 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1973 | 3,4,4',5-Tetrabromobiphenyl 59589-92-3 | C12H6Br4 469.792 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1974 | 2,2',4,5'-Tetrabromobiphenyl 60044-24-8 | C12H6Br4 469.792 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1975 | 2,2',5,6'-Tetrabromobiphenyl 60044-25-9 | C12H6Br4 469.792 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1978 | 2,4,4',6-Tetrabromobiphenyl 64258-02-2 | C12H6Br4 469.792 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1981 | 2,2',4,4'-Tetrabromobiphenyl 66115-57-9 | C12H6Br4 469.792 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1996 | 3,3',4,4'-Tetrabromobiphenyl 77102-82-0 | C12H6Br4 469.792 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D2009 | 2,3',4,4'-Tetrabromobiphenyl 84303-45-7 | C12H6Br4 469.792 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |