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Displaying toxin 3351 - 3375 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D3999Perfluorodecanoic acid
335-76-2
C10HF19O2
514.083 g/mol
Thumb
  • Food Toxin
  • Organic Compound
  • Organofluoride
  • Pollutant
  • Synthetic Compound
Not Available
Number of Targets: 5
T3D3711Roridin E
16891-85-3
C29H38O8
514.607 g/mol
Thumb
  • Ester
  • Ether
  • Fungal Toxin
  • Lachrymator
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more
Number of Targets: 2
T3D1747Platinum(IV) bromide
68936-92-1
Br4Pt
514.700 g/mol
Thumb
  • Bromide Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Synthetic Compound
Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more
Number of Targets: 6
T3D3778Paspalitrem B
63764-58-9
C32H39NO5
517.656 g/mol
Thumb
  • Ester
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more
Number of Targets: 27
T3D3730Rubratoxin B
21794-01-4
C26H30O11
518.510 g/mol
Thumb
  • Ester
  • Ether
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Rubratoxin B is cytotoxic, hinders cell proliferation, and induces apoptosis. It also inhibits the activity of matrix metalloproteinase-2 and -9. Rubratoxin B causes d...more
Number of Targets: 20
T3D3081(-)-Gossypol
90141-22-3
C30H30O8
518.554 g/mol
Thumb
  • Ester
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Gossypol may cause apoptosis via the regulation of Bax and Bcl-2 proteins. It is also an inhibitor of calcineurin and protein kinases C, and has been shown to bind cal...more
Number of Targets: 23
T3D3731Rubratoxin A
22467-31-8
C26H32O11
520.526 g/mol
Thumb
  • Ester
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Rubratoxin A is a potent inhibitor of protein phosphatase 2A, exerting antitumor and antimetastatic effects. Inhibition may cause the phosphorylation of CREB and subse...more
Number of Targets: 12
T3D3101Brodifacoum
56073-10-0
C31H23BrO3
523.417 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Bromide Compound
  • Ester
  • Household Toxin
  • Organic Compound
  • Organobromide
  • Pesticide
  • Synthetic Compound
Brodifacoum inhibits the enzyme Vitamin K epoxide reductase. This enzyme is needed for the reconstitution of the vitamin K in its cycle from vitamin K-epoxide, and so ...more
Number of Targets: 1
T3D1767Tungsten(VI) oxytetrabromide
13520-77-9
Br4H4OW
523.490 g/mol
Thumb
  • Bromide Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Synthetic Compound
Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more
Number of Targets: 6
T3D3745Territrem B
70407-20-4
C29H34O9
526.575 g/mol
Thumb
  • Ester
  • Ether
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Territrem B is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinest...more
Number of Targets: 2
T3D0381Cadmium phosphate
13477-17-3
Cd3O8P2
527.176 g/mol
Thumb
  • Amine
  • Cadmium Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
Cadmium initially binds to metallothionein and is transported to the kidney. Toxic effects are observed once the concentration of cadmium exceeds that of available met...more
Number of Targets: 19
T3D3102Bromadiolone
28772-56-7
C30H23BrO4
527.405 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Bromide Compound
  • Ester
  • Organic Compound
  • Organobromide
  • Pesticide
  • Synthetic Compound
Bromadiolone inhibits the enzyme Vitamin K epoxide reductase. This enzyme is needed for the reconstitution of the vitamin K in its cycle from vitamin K-epoxide, and so...more
Number of Targets: 1
T3D2861Daunorubicin
20830-81-3
C27H29NO10
527.520 g/mol
Thumb
  • Amine
  • Antibiotic
  • Antibiotic, Antineoplastic
  • Antineoplastic Agent
  • Drug
  • Ester
  • Ether
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Daunorubicin has antimitotic and cytotoxic activity through a number of proposed mechanisms of action: Daunorubicin forms complexes with DNA by intercalation between b...more
Number of Targets: 7
T3D3864Indoxacarb
173584-44-6
C22H17ClF3N3O7
527.834 g/mol
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  • Amine
  • Carbamate
  • Ester
  • Ether
  • Household Toxin
  • Insecticide
  • Organic Compound
  • Organochloride
  • Organofluoride
  • Pesticide
  • Synthetic Compound
It is thought that indoxacarb's aromatic metabolites biotransform to active intermediates that produce methemoglobin (A15207). The mechanism of indoxacarb-induced rena...more
Number of Targets: 30
T3D3712Satratoxin H
53126-64-0
C29H36O9
528.591 g/mol
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  • Ester
  • Ether
  • Fungal Toxin
  • Lachrymator
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more
Number of Targets: 2
T3D3865Iodosulfuron-methyl-sodium
144550-36-7
C14H13IN5NaO6S
529.242 g/mol
Thumb
  • Amide
  • Amine
  • Ester
  • Ether
  • Herbicide
  • Organic Compound
  • Pesticide
  • Synthetic Compound
Not Available
Number of Targets: 2
T3D3710Roridin D
14682-29-2
C29H38O9
530.607 g/mol
Thumb
  • Ester
  • Ether
  • Fungal Toxin
  • Lachrymator
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more
Number of Targets: 2
T3D3650Diisotridecyl phthalate
68515-47-9
C34H58O4
530.822 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Cosmetic Toxin
  • Ester
  • Ether
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Phthalate
  • Plasticizer
  • Synthetic Compound
Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more
Number of Targets: 0
T3D3656Ditridecyl phthalate
119-06-2
C34H58O4
530.822 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Cosmetic Toxin
  • Ester
  • Ether
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Phthalate
  • Plasticizer
  • Synthetic Compound
Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more
Number of Targets: 0
T3D2961Ketoconazole
65277-42-1
C26H28Cl2N4O4
531.431 g/mol
Thumb
  • 14-alpha Demethylase Inhibitor
  • Amide
  • Amine
  • Antifungal Agent
  • Cosmetic Toxin
  • Drug
  • Ether
  • Food Toxin
  • Household Toxin
  • Metabolite
  • Organic Compound
  • Organochloride
  • Synthetic Compound
Ketoconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary for the conversion of lanosterol to ergosterol. This results in inhibition of ergoste...more
Number of Targets: 26
T3D3709Roridin A
14729-29-4
C29H40O9
532.623 g/mol
Thumb
  • Ester
  • Ether
  • Fungal Toxin
  • Lachrymator
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more
Number of Targets: 2
T3D3691Ergovaline
2873-38-3
C29H35N5O5
533.619 g/mol
Thumb
  • Amide
  • Amine
  • Ether
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agonism or antagonism at adrenergic, dopaminergic, and serotonergic recept...more
Number of Targets: 7
T3D4858Acid yellow 23
1934-21-0
C16H9N4Na3O9S2
534.363 g/mol
Thumb
  • Ester
  • Food Additive
  • Food Toxin
  • Household Toxin
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Not Available
Number of Targets: 2
T3D1562Tris(dodecyl)aluminum
1529-59-5
C36H75Al
534.962 g/mol
Thumb
  • Aluminum Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organometallic
  • Synthetic Compound
The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more
Number of Targets: 3
T3D1840Thallium selenide
12039-52-0
O3SeTl2
535.720 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Pollutant
  • Selenium Compound
  • Synthetic Compound
Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more
Number of Targets: 0
Displaying toxin 3351 - 3375 of 3678 in total