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Displaying toxin 3426 - 3450 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D1258Tetra-n-octylstannane
3590-84-9
C32H68Sn
571.590 g/mol
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  • Industrial/Workplace Toxin
  • Organic Compound
  • Organometallic
  • Synthetic Compound
  • Tin Compound
Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more
Number of Targets: 12
T3D1183Uranyl zinc acetate
10138-94-0
C8H12O10UZn
571.613 g/mol
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  • Industrial/Workplace Toxin
  • Organic Compound
  • Organometallic
  • Pollutant
  • Radioactive
  • Synthetic Compound
  • Uranium Compound
  • Zinc Compound
Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and prot...more
Number of Targets: 2
T3D1388Tetracobalt dodecacarbonyl
17786-31-1
C12Co4O12
571.854 g/mol
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  • Cobalt Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Organic Compound
  • Organometallic
  • Pollutant
  • Synthetic Compound
Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more
Number of Targets: 35
T3D4032Cyclochlorotine
12663-46-6
C24H31Cl2N5O7
572.438 g/mol
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  • Amide
  • Amine
  • Food Toxin
  • Fungal Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Organochloride
Cyclochlorotine (CC) causes hepatic necrosis and has carcinogenic properties. The in vitro application of CC on myocytes induced disruption of myofibrils and large acc...more
Number of Targets: 0
T3D0871Antimony pentasulfide
1315-04-4
C30H40N2O7S
572.713 g/mol
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  • Amide
  • Amine
  • Antimony Compound
  • Ether
  • Food Toxin
  • Inorganic Compound
  • Organic Compound
  • Pollutant
  • Synthetic Compound
The inhalation data suggest that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes ...more
Number of Targets: 20
T3D1147Manganese phthalocyanine
14325-24-7
C32H22MnN8
573.509 g/mol
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  • Cyanide Compound
  • Food Toxin
  • Inorganic Compound
  • Manganese Compound
  • Organic Compound
  • Pollutant
  • Synthetic Compound
Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particu...more
Number of Targets: 44
T3D3693Xanthomegnin
1685-91-2
C30H22O12
574.489 g/mol
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  • Ester
  • Ether
  • Food Toxin
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Not Available
Number of Targets: 0
T3D3768Luteoskyrin
21884-44-6
C30H22O12
574.489 g/mol
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  • Ester
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Luteoskyrin is hepatotoxic. It is thought that this is a result of its metabolic reduction to the semiquinone radical catalyzed by NADPH-dependent cytochrome reductase...more
Number of Targets: 26
T3D3690Ergocryptine
511-09-1
C32H41N5O5
575.698 g/mol
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  • Amide
  • Amine
  • Ether
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agonism or antagonism at adrenergic, dopaminergic, and serotonergic recept...more
Number of Targets: 4
T3D1313Thorin
3688-92-4
C16H11AsN2Na2O10S2
576.297 g/mol
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  • Aromatic Hydrocarbon
  • Arsenic Compound
  • Ester
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organometallic
  • Synthetic Compound
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more
Number of Targets: 44
T3D3094Oleandrin
465-16-7
C32H48O9
576.718 g/mol
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  • Ester
  • Ether
  • Lachrymator
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Oleandrin likely exerts its toxic effects by inhibiting Na+,K+-ATPase. (A2831)
Number of Targets: 9
T3D1583Bis(1,5-diphenyl-1,4-pentadien-3-one) palladium(0)
32005-36-0
C34H30O2Pd
577.020 g/mol
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  • Aromatic Hydrocarbon
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organometallic
  • Palladium Compound
  • Synthetic Compound
Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more
Number of Targets: 6
T3D1897Triphenylcarbenium hexachloroantimonate
52704-88-8
C19H15Cl6Sb
577.800 g/mol
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  • Antimony Compound
  • Aromatic Hydrocarbon
  • Food Toxin
  • Organic Compound
  • Organometallic
  • Pollutant
  • Synthetic Compound
The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more
Number of Targets: 20
T3D21321,2,3,4,6,7,8,9,10,10,11,11-Dodecachloro-1,4,4a,5a,6,9,9a,9b-octahydro-1,4:6,9- dimethanodibenzofuran
31107-44-5
C14H5Cl11O
579.172 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D3742Fumitremorgin A
12626-18-5
C32H41N3O7
579.684 g/mol
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  • Amide
  • Amine
  • Ether
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more
Number of Targets: 22
T3D1758Tantalum(V) bromide
13451-11-1
Br5Ta
580.468 g/mol
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  • Bromide Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Synthetic Compound
Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more
Number of Targets: 6
T3D2460Ergotamine
113-15-5
C33H35N5O5
581.662 g/mol
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  • Adrenergic alpha-Agonist
  • Amide
  • Amine
  • Analgesic, Non-Narcotic
  • Drug
  • Ether
  • Fungal Toxin
  • Metabolite
  • Mycotoxin
  • Natural Compound
  • Organic Compound
  • Sympatholytic
  • Vasoconstrictor Agent
Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agonism or antagonism at adrenergic, dopaminergic, and serotonergic recept...more
Number of Targets: 16
T3D1766Tungsten(V) bromide
13470-11-6
Br5W
583.360 g/mol
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  • Bromide Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Synthetic Compound
Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more
Number of Targets: 6
T3D2750Dihydroergotamine
6190-39-2
C33H37N5O5
583.677 g/mol
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  • Amide
  • Amine
  • Analgesic
  • Analgesic, Non-Narcotic
  • Anti-Migraine Agent
  • Dopamine Agonist
  • Drug
  • Ether
  • Metabolite
  • Organic Compound
  • Sympatholytic
  • Synthetic Compound
  • Vasoconstrictor Agent
Two theories have been proposed to explain the efficacy of 5-HT1D receptor agonists in migraine: 1) activation of 5-HT1D receptors located on intracranial blood vessel...more
Number of Targets: 12
T3D3733Penitrem B
11076-67-8
C37H45NO5
583.757 g/mol
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  • Ether
  • Food Toxin
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more
Number of Targets: 27
T3D4018Ouabain
630-60-4
C29H44O12
584.653 g/mol
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  • Cardiotonic Agent
  • Drug
  • Enzyme Inhibitor
  • Ester
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Ouabain inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations. Increased intracellular concentrations of ...more
Number of Targets: 6
T3D4350Bilirubin
635-65-4
C33H36N4O6
584.662 g/mol
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  • Animal Toxin
  • Food Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
Not Available
Number of Targets: 2
T3D3762Janthitrem B
73561-90-7
C37H47NO5
585.773 g/mol
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  • Ether
  • Food Toxin
  • Fungal Toxin
  • Metabolite
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more
Number of Targets: 22
T3D4695Etoposide
33419-42-0
C29H32O13
588.557 g/mol
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  • Antineoplastic Agent, Phytogenic
  • Drug
  • Ester
  • Ether
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Etoposide inhibits DNA topoisomerase II, thereby inhibiting DNA re-ligation. This causes critical errors in DNA synthesis at the premitotic stage of cell division and ...more
Number of Targets: 2
T3D1901Tris(4-bromophenyl)antimony
17946-45-1
C18H12Br3Sb
589.760 g/mol
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  • Antimony Compound
  • Aromatic Hydrocarbon
  • Bromide Compound
  • Food Toxin
  • Organic Compound
  • Organobromide
  • Organometallic
  • Pollutant
  • Synthetic Compound
The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more
Number of Targets: 20
Displaying toxin 3426 - 3450 of 3678 in total