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Displaying toxin 3501 - 3525 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D3732Penitrem A
12627-35-9
C37H44ClNO6
634.201 g/mol
Thumb
  • Ether
  • Food Toxin
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
  • Organochloride
Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more
Number of Targets: 27
T3D3774Secalonic Acid D
35287-69-5
C32H30O14
638.572 g/mol
Thumb
  • Ester
  • Ether
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Secalonic acid D (SAD) is though to induce cleft palate by causing the formation of smaller palatal shelves that fail to elevate and fuse. This inhibited palatal shelf...more
Number of Targets: 4
T3D3758Enniatin B
917-13-5
C33H57N3O9
639.820 g/mol
Thumb
  • Amide
  • Amine
  • Ester
  • Ether
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Enniatins are toxic due to their ability to act as ionophores, changing ion transport across membranes and disrupting the ionic selectivity of cell walls. In the membr...more
Number of Targets: 5
T3D21371,2,3,4,6,7-Hexabromodibenzofuran
124388-78-9
C12H2Br6O
641.568 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Bromide Compound
  • Brominated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organobromide
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D21451,2,3,4,7,8-Hexabromodibenzofuran
129880-08-6
C12H2Br6O
641.568 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Bromide Compound
  • Brominated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organobromide
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D21541,2,3,6,7,8-Hexabromodibenzofuran
107555-94-2
C12H2Br6O
641.568 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Bromide Compound
  • Brominated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organobromide
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D21621,2,3,7,8,9-Hexabromodibenzofuran
161880-49-5
C12H2Br6O
641.568 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Bromide Compound
  • Brominated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organobromide
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D22282,3,4,6,7,8-Hexabromodibenzofuran
161880-50-8
C12H2Br6O
641.568 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Bromide Compound
  • Brominated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organobromide
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D1800Hexabromocyclododecane
25637-99-4
C12H18Br6
641.695 g/mol
Thumb
  • Bromide Compound
  • Household Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Pollutant
  • Synthetic Compound
Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more
Number of Targets: 3
T3D2041Hexabromobiphenyl Ether
36483-60-0
C12H4Br6O
643.584 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Bromide Compound
  • Ether
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
Like other halogenated aromatic hydrocarbons, polybrominated diphenyl ethers bind to the cellular aryl hydrocarbon receptor (AhR), which regulates the synthesis of a v...more
Number of Targets: 6
T3D4737Amiodarone
1951-25-3
C25H29I2NO3
645.312 g/mol
Thumb
  • Amine
  • Anti-Arrhythmia Agent
  • Drug
  • Enzyme Inhibitor
  • Ester
  • Ether
  • Organic Compound
  • Synthetic Compound
  • Vasodilator Agent
The antiarrhythmic effect of amiodarone may be due to at least two major actions. It prolongs the myocardial cell-action potential (phase 3) duration and refractory pe...more
Number of Targets: 4
T3D3078Aconitine
302-27-2
C34H47NO11
645.737 g/mol
Thumb
  • Amine
  • Ester
  • Ether
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Aconitine opens voltage-gated sodium channed in the heart and other tissues. (L1235)
Number of Targets: 14
T3D3765Janthitrem F
90986-52-0
C39H51NO7
645.825 g/mol
Thumb
  • Ester
  • Ether
  • Food Toxin
  • Fungal Toxin
  • Metabolite
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more
Number of Targets: 22
T3D4759Liothyronine
6893-02-3
C15H12I3NO4
650.974 g/mol
Thumb
  • Amine
  • Animal Toxin
  • Drug
  • Ether
  • Food Toxin
  • Hormone Replacement Agent
  • Metabolite
  • Natural Compound
  • Organic Compound
The hormones, T4 and T3, are tyrosine-based hormones produced by the thyroid gland. Iodine is an important component in their synthesis. The major form of thyroid horm...more
Number of Targets: 10
T3D3759Enniatin B1
19914-20-6
C34H59N3O9
653.847 g/mol
Thumb
  • Amide
  • Amine
  • Ester
  • Ether
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Enniatins are toxic due to their ability to act as ionophores, changing ion transport across membranes and disrupting the ionic selectivity of cell walls. In the membr...more
Number of Targets: 5
T3D3017Bromocriptine
25614-03-3
C32H40BrN5O5
654.595 g/mol
Thumb
  • Amide
  • Amine
  • Antidyskinetic
  • Antiparkinson Agent
  • Bromide Compound
  • Dopamine Agonist
  • Drug
  • Ether
  • Hormone Antagonist
  • Metabolite
  • Organic Compound
  • Organobromide
  • Synthetic Compound
The dopamine D2 receptor is a 7-transmembrane G-protein coupled receptor associated with Gi proteins. In lactotrophs, stimulation of dopamine D2 receptor causes inhibi...more
Number of Targets: 25
T3D4323Coproporphyrin III
14643-66-4
C36H38N4O8
654.709 g/mol
Thumb
  • Animal Toxin
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Not Available
Number of Targets: 1
T3D0351Mercury(I) iodide
15385-57-6
Hg2I2
654.990 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Mercury Compound
  • Pollutant
  • Synthetic Compound
High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more
Number of Targets: 50
T3D4715Teniposide
29767-20-2
C32H32O13S
656.654 g/mol
Thumb
  • Antineoplastic Agent
  • Drug
  • Enzyme Inhibitor
  • Ester
  • Ether
  • Metabolite
  • Nucleic Acid Synthesis Inhibitor
  • Organic Compound
  • Synthetic Compound
The mechanism of action appears to be related to the inhibition of type II topoisomerase activity since teniposide does not intercalate into DNA or bind strongly to DN...more
Number of Targets: 1
T3D4438Coproporphyrinogen III
2624-63-7
C36H44N4O8
660.757 g/mol
Thumb
  • Animal Toxin
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
Not Available
Number of Targets: 1
T3D1852Tralomethrin
66841-25-6
C22H19Br4NO3
665.007 g/mol
Thumb
  • Bromide Compound
  • Ester
  • Ether
  • Household Toxin
  • Nitrile
  • Organic Compound
  • Organobromide
  • Pesticide
  • Pyrethroid
  • Synthetic Compound
Pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase i...more
Number of Targets: 20
T3D0873Antimony potassium tartrate
28300-74-5
C8H10K2O15Sb2
667.870 g/mol
Thumb
  • Antimony Compound
  • Food Toxin
  • Inorganic Compound
  • Organic Compound
  • Pollutant
  • Synthetic Compound
The inhalation data suggest that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes ...more
Number of Targets: 23
T3D3757Enniatin A1
4530-21-6
C35H61N3O9
667.874 g/mol
Thumb
  • Amide
  • Amine
  • Ester
  • Ether
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Enniatins are toxic due to their ability to act as ionophores, changing ion transport across membranes and disrupting the ionic selectivity of cell walls. In the membr...more
Number of Targets: 5
T3D4235Aplysiatoxin
52659-57-1
C32H47BrO10
671.614 g/mol
Thumb
  • Bacterial Toxin
  • Bromide Compound
  • Ester
  • Ether
  • Marine Toxin
  • Natural Compound
  • Organic Compound
  • Organobromide
Aplysiatoxin is a 12-O-tetradecanoylphorbol-13-acetate (TPA)-type tumor promoter that activates protein kinase C (PKC) (A15358). In cancer cells, PKC isozymes are invo...more
Number of Targets: 1
T3D4061Veratridine
71-62-5
C36H51NO11
673.790 g/mol
Thumb
  • Amine
  • Ester
  • Ether
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Veratridine is a steroid-derived alkaloid from plants in the Liliaceae family that functions as a neurotoxin by abolishing inactivation of sodium ion channels. It bind...more
Number of Targets: 0
Displaying toxin 3501 - 3525 of 3678 in total