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Displaying toxin 3576 - 3600 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D19932,2',3,3',4,5',6,6'-Octabromobiphenyl
69887-11-2
C12H2Br8
785.376 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Bromide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more
Number of Targets: 1
T3D0362Mercuric potassium iodide
7783-33-7
HgI4K2
786.400 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Mercury Compound
  • Pollutant
  • Synthetic Compound
High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more
Number of Targets: 50
T3D2467Phalloidin
17466-45-4
Not Available
3301.700 g/mol
T3d2467
  • Amide
  • Amine
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
  • Phallotoxin
  • Protein
It binds actin, preventing its depolymerization and poisoning the cell. Phalloidin binds specifically at the interface between F-actin subunits, locking adjacent subun...more
Number of Targets: 6
T3D4864Erioglaucine A disodium salt
3844-45-9
C37H34N2Na2O9S3
792.848 g/mol
Thumb
  • Amine
  • Food Additive
  • Food Toxin
  • Household Toxin
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Not Available
Number of Targets: 5
T3D1547Aluminum palmitate
555-35-1
C48H93AlO6
793.230 g/mol
Thumb
  • Aluminum Compound
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organometallic
  • Synthetic Compound
The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more
Number of Targets: 3
T3D20432,3,3',4,4',5,5',6'-Octabromobiphenyl Ether
32536-52-0
C12H2Br8O
801.376 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Bromide Compound
  • Ether
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
Like other halogenated aromatic hydrocarbons, polybrominated diphenyl ethers bind to the cellular aryl hydrocarbon receptor (AhR), which regulates the synthesis of a v...more
Number of Targets: 6
T3D4732Tacrolimus
104987-11-3
C44H69NO12
804.018 g/mol
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  • Amide
  • Amine
  • Drug
  • Ester
  • Ether
  • Organic Compound
  • Synthetic Compound
The mechanism of action of tacrolimus in atopic dermatitis is not known. While the following have been observed, the clinical significance of these observations in ato...more
Number of Targets: 1
T3D2470Phallisin
19774-69-7
C35H48N8O12S
804.867 g/mol
Thumb
  • Amide
  • Amine
  • Ether
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
  • Phallotoxin
Phallotoxins bind actin, preventing its depolymerization and poisoning the cell. They bind specifically at the interface between F-actin subunits, locking adjacent sub...more
Number of Targets: 6
T3D4029Okadaic acid
78111-17-8
C44H68O13
805.003 g/mol
Thumb
  • Animal Toxin
  • Ether
  • Food Toxin
  • Ionophore
  • Marine Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
Okadaic acid (OA) dramatically increases both nerve growth factor (NGF) mRNA content (50-fold) and NGF secretion (100-fold) in astrocytes. Okadaic acid also activated ...more
Number of Targets: 1
T3D1331Lead subacetate
1335-32-6
C4H10O8Pb3
807.700 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Lead Compound
  • Organic Compound
  • Organometallic
  • Pollutant
  • Synthetic Compound
Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more
Number of Targets: 29
T3D3501Docetaxel
114977-28-5
C43H53NO14
807.879 g/mol
Thumb
  • Amine
  • Antimalarial
  • Antineoplastic Agent
  • Antineoplastic Agent, Phytogenic
  • Drug
  • Ester
  • Ether
  • Metabolite
  • Organic Compound
  • Radiation-Sensitizing Agent
  • Synthetic Compound
Docetaxel interferes with the normal function of microtubule growth. Whereas drugs like colchicine cause the depolymerization of microtubules in vivo, docetaxel arrest...more
Number of Targets: 9
T3D4017Vinblastine
865-21-4
C46H58N4O9
810.974 g/mol
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  • Amine
  • Antineoplastic Agent, Phytogenic
  • Drug
  • Ester
  • Ether
  • Metabolite
  • Organic Compound
  • Synthetic Compound
  • Tubulin Modulator
The antitumor activity of vinblastine is thought to be due primarily to inhibition of mitosis at metaphase through its interaction with tubulin. Vinblastine binds to t...more
Number of Targets: 6
T3D0333Lead phosphate
7446-27-7
O8P2Pb3
811.500 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Lead Compound
  • Pollutant
  • Synthetic Compound
Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more
Number of Targets: 29
T3D3536Telithromycin
191114-48-4
C43H65N5O10
812.004 g/mol
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  • Amine
  • Anti-Bacterial Agent
  • Drug
  • Ester
  • Ether
  • Ketolide
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Telithromycin acts by binding to domains II and V of 23S rRNA of the 50S ribosomal subunit. By binding at domain II, telithromycin retains activity against gram-positi...more
Number of Targets: 6
T3D1900Tris(4-bromophenyl)aminium hexachloroantimonate
24964-91-8
C18H12Br3Cl6NSb
816.480 g/mol
Thumb
  • Amine
  • Antimony Compound
  • Aromatic Hydrocarbon
  • Bromide Compound
  • Food Toxin
  • Organic Compound
  • Organobromide
  • Organometallic
  • Pollutant
  • Synthetic Compound
The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more
Number of Targets: 20
T3D4030Dinophysistoxin 1
81720-10-7
C45H70O13
819.030 g/mol
Thumb
  • Animal Toxin
  • Ether
  • Food Toxin
  • Marine Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
Dinophysistoxin 1 (DTX1) is the analogue of okadaic acid causing diarrheic shellfish poisoning (DSP) in humans shortly after the ingestion of contaminated seafood. DTX...more
Number of Targets: 0
T3D2969Rifampin
13292-46-1
C43H58N4O12
822.940 g/mol
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  • Amide
  • Amine
  • Antibiotic
  • Antibiotic, Antitubercular
  • Antitubercular Agent
  • Antituberculosis Agent
  • Drug
  • Enzyme Inhibitor
  • Ester
  • Ether
  • Hydrazine
  • Leprostatic Agent
  • Metabolite
  • Nucleic Acid Synthesis Inhibitor
  • Organic Compound
  • Synthetic Compound
Rifampin acts via the inhibition of DNA-dependent RNA polymerase, leading to a suppression of RNA synthesis and cell death.
Number of Targets: 10
T3D4447Propionyl-CoA
317-66-8
C24H40N7O17P3S
823.597 g/mol
Thumb
  • Amine
  • Animal Toxin
  • Ester
  • Ether
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
In propionic aciduria, propionyl CoA accumulates within the mitochondria in massive quantities; free carnitine is then esterified, creating propionyl carnitine, which ...more
Number of Targets: 0
T3D4016Vincristine
57-22-7
C46H56N4O10
824.958 g/mol
Thumb
  • Amide
  • Amine
  • Antineoplastic Agent, Phytogenic
  • Drug
  • Ester
  • Ether
  • Metabolite
  • Organic Compound
  • Synthetic Compound
  • Tubulin Modulator
The antitumor activity of Vincristine is thought to be due primarily to inhibition of mitosis at metaphase through its interaction with tubulin. Like other vinca alkal...more
Number of Targets: 7
T3D3616Nodularin-R
118399-22-7
C41H60N8O10
824.963 g/mol
Thumb
  • Amide
  • Amine
  • Bacterial Toxin
  • Ester
  • Ether
  • Microcystin
  • Natural Compound
  • Organic Compound
The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more
Number of Targets: 23
T3D3098Alcuronium
23214-96-2
C44H50Br2N4O2
826.701 g/mol
Thumb
  • Amine
  • Bromide Compound
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotinic acetylcholine receptors. (L1256)
Number of Targets: 17
T3D4322Uroporphyrin III
18273-06-8
C40H38N4O16
830.747 g/mol
Thumb
  • Animal Toxin
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
Not Available
Number of Targets: 1
T3D4324Uroporphyrin I
607-14-7
C40H38N4O16
830.747 g/mol
Thumb
  • Animal Toxin
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
Not Available
Number of Targets: 0
T3D2472Phallacin
53568-40-4
C37H50N8O12S
830.904 g/mol
Thumb
  • Amide
  • Amine
  • Ether
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
  • Phallotoxin
Phallotoxins bind actin, preventing its depolymerization and poisoning the cell. They bind specifically at the interface between F-actin subunits, locking adjacent sub...more
Number of Targets: 6
T3D2672Azaspiracid
214899-21-5
C47H71NO12
842.066 g/mol
Thumb
  • Amine
  • Animal Toxin
  • Ether
  • Food Toxin
  • Marine Toxin
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Azaspiracid-4 dose-dependent inhibits the increase in cytosolic Ca2+ levels induced by thapsigargin (Tg) (A330). Azaspiracid-2 and Azaspiracid-3 clearly increase cytos...more
Number of Targets: 1
Displaying toxin 3576 - 3600 of 3678 in total