You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on Toxin, Toxin Target Database.
Displaying toxin 3651 - 3675 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D3614Microcystin-LW
157622-02-1
C54H72N8O12
1025.196 g/mol
Thumb
  • Amide
  • Amine
  • Bacterial Toxin
  • Ether
  • Microcystin
  • Natural Compound
  • Organic Compound
The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more
Number of Targets: 23
T3D3609Microcystin-RR
111755-37-4
C49H75N13O12
1038.200 g/mol
Thumb
  • Amide
  • Amine
  • Bacterial Toxin
  • Ether
  • Microcystin
  • Natural Compound
  • Organic Compound
The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more
Number of Targets: 23
T3D2566Heparin
9005-49-6
C26H41NO34S4
1039.850 g/mol
Thumb
  • Animal Toxin
  • Anticoagulant
  • Drug
  • Ester
  • Fibrinolytic Agent
  • Food Toxin
  • Heparin
  • Metabolite
  • Natural Compound
  • Organic Compound
Heparin-induced thrombocytopenia (HIT) is caused by the formation of abnormal antibodies that activate platelets. Heparin occurs naturally in the human body, but the d...more
Number of Targets: 14
T3D3608Microcystin-YR
101064-48-6
C52H72N10O13
1045.187 g/mol
Thumb
  • Amide
  • Amine
  • Bacterial Toxin
  • Ether
  • Microcystin
  • Natural Compound
  • Organic Compound
The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more
Number of Targets: 23
T3D1286Hexakis(2-methyl-2-phenylpropyl)distannoxane
13356-08-6
C60H80OSn2
1054.700 g/mol
Thumb
  • Food Toxin
  • Household Toxin
  • Metabolite
  • Organic Compound
  • Organometallic
  • Pesticide
  • Synthetic Compound
  • Tin Compound
Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more
Number of Targets: 12
T3D2466Ciguatoxin 4B
123676-76-6
C60H84O16
1061.299 g/mol
Thumb
  • Animal Toxin
  • Ether
  • Marine Toxin
  • Natural Compound
  • Organic Compound
Ciguatoxin lowers the threshold for opening voltage-gated sodium channels in synapses of the nervous system. The effect of opening a sodium channel will cause depolari...more
Number of Targets: 14
T3D2464Ciguatoxin 2
142185-85-1
C60H86O18
1095.314 g/mol
Thumb
  • Animal Toxin
  • Ether
  • Food Toxin
  • Marine Toxin
  • Natural Compound
  • Organic Compound
Ciguatoxin lowers the threshold for opening voltage-gated sodium channels in synapses of the nervous system. The effect of opening a sodium channel will cause depolari...more
Number of Targets: 14
T3D246554-Deoxyciguatoxin
139341-09-6
C60H86O18
1095.314 g/mol
Thumb
  • Animal Toxin
  • Ether
  • Food Toxin
  • Marine Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
Ciguatoxin lowers the threshold for opening voltage-gated sodium channels in synapses of the nervous system. The effect of opening a sodium channel will cause depolari...more
Number of Targets: 14
T3D2463Ciguatoxin 1
11050-21-8
C60H86O19
1111.313 g/mol
Thumb
  • Animal Toxin
  • Ether
  • Food Toxin
  • Marine Toxin
  • Natural Compound
  • Organic Compound
Ciguatoxin lowers the threshold for opening voltage-gated sodium channels in synapses of the nervous system. The effect of opening a sodium channel will cause depolari...more
Number of Targets: 14
T3D3067Vapreotide
103222-11-3
C57H70N12O9S2
1131.371 g/mol
Thumb
  • Amide
  • Amine
  • Analgesic
  • Antineoplastic Agent
  • Drug
  • Metabolite
  • Organic Compound
  • Synthetic Compound
The exact mechanism of action is unknown, although one study has provided in vitro and in vivo evidence for a tachykinin NK1 receptor antagonist effect in the analgesi...more
Number of Targets: 3
T3D2763Anidulafungin
166663-25-8
C58H73N7O17
1140.237 g/mol
Thumb
  • Amide
  • Amine
  • Antibiotic, Antifungal
  • Antifungal Agent
  • Drug
  • Ester
  • Ether
  • Food Toxin
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Anidulafungin is a semi-synthetic echinocandin with antifungal activity. Anidulafungin inhibits glucan synthase, an enzyme present in fungal, but not mammalian cells. ...more
Number of Targets: 6
T3D1579Tetrakis(triphenylphosphine)palladium(0)
14221-01-3
C72H64P4Pd
1159.590 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organometallic
  • Palladium Compound
  • Synthetic Compound
Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more
Number of Targets: 6
T3D3498Cyclosporin
59865-13-3
C62H111N11O12
1202.611 g/mol
Thumb
  • Amide
  • Amine
  • Antifungal Agent
  • Antirheumatic Agent
  • Dermatologic Agent
  • Drug
  • Enzyme Inhibitor
  • Fungal Toxin
  • Immunomodulatory Agent
  • Immunosuppressive Agent
  • Natural Compound
  • Organic Compound
Cyclosporine binds to cyclophilin. The complex then inhibits calcineurin which is normally responsible for activating transcription of interleukin 2. Cyclosporine also...more
Number of Targets: 7
T3D3529Polymyxin B Sulfate
1405-20-5
C56H98N16O13
1203.477 g/mol
Thumb
  • Amide
  • Amine
  • Anti-Bacterial Agent
  • Drug
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Polymyxin B sulfate has a bactericidal action against almost all gram-negative bacilli except the Proteus group. Polymyxin B sulfate interacts with the lipopolysacchar...more
Number of Targets: 0
T3D4915gamma-Cyclodextrin
17465-86-0
C48H80O40
1297.125 g/mol
Thumb
  • Food Toxin
  • Household Toxin
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Not Available
Number of Targets: 1
T3D1097Barium cadmium stearate
1191-79-3
C72H148BaCaO8
1319.346 g/mol
Thumb
  • Barium Compound
  • Cadmium Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Pollutant
  • Synthetic Compound
Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to...more
Number of Targets: 40
T3D2855Nafarelin
76932-56-4
C66H83N17O13
1322.471 g/mol
Thumb
  • Amide
  • Amine
  • Antiendometriotic Agent
  • Drug
  • Fertility Agent, Female
  • Gonadotropin-Releasing Hormone
  • Gonadotropin-releasing hormone agonist
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Like GnRH, initial or intermittent administration of nafarelin stimulates release of the gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH) ...more
Number of Targets: 2
T3D0679Methylcobalamin
13422-55-4
C63H91CoN13O14P
1344.382 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Cobalt Compound
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Organometallic
  • Pollutant
Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more
Number of Targets: 35
T3D0677Hydroxocobalamin
13422-51-0
C62H89CoN13O15P
1346.355 g/mol
Thumb
  • Amide
  • Amine
  • Anti-Anemic Agent
  • Cobalt Compound
  • Drug
  • Ether
  • Food Toxin
  • Hematinic
  • Metabolite
  • Natural Compound
  • Nutritional Supplement
  • Nutritional Support
  • Organic Compound
  • Pollutant
  • Vitamin B Complex
Vitamin B12 exists in four major forms referred to collectively as cobalamins; deoxyadenosylcobalamin, methylcobalamin, hydroxocobalamin, and cyanocobalamin. Two of th...more
Number of Targets: 45
T3D0673Cyanocobalamin
68-19-9
C63H88CoN14O14P
1355.365 g/mol
Thumb
  • Anti-Anemic Agent
  • Cobalt Compound
  • Drug
  • Essential Vitamin
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Nutraceutical
  • Pollutant
  • Vitamin
  • Vitamin B Complex
Vitamin B12 is used in the body in two forms: Methylcobalamin and 5-deoxyadenosyl cobalamin. The enzyme methionine synthase needs methylcobalamin as a cofactor. This e...more
Number of Targets: 46
T3D2738Bleomycin
11056-06-7
C55H84N17O21S3
1415.551 g/mol
Thumb
  • Amide
  • Amine
  • Antibiotic, Antineoplastic
  • Antimetabolite
  • Drug
  • Ester
  • Lachrymator
  • Metabolite
  • Organic Compound
  • Synthetic Compound
It has been suggested that bleomycin induces sensitivity to oxygen toxicity and recent studies support the role of the proinflammatory cytokines IL-18 and IL-1beta in ...more
Number of Targets: 4
T3D3543Vancomycin
1404-90-6
C66H75Cl2N9O24
1449.254 g/mol
Thumb
  • Amine
  • Anti-Bacterial Agent
  • Drug
  • Ether
  • Glycopeptide Antibacterial
  • Metabolite
  • Organic Compound
  • Organochloride
  • Synthetic Compound
The bactericidal action of vancomycin results primarily from inhibition of cell-wall biosynthesis. Specifically, vancomycin prevents incorporation of N-acetylmuramic a...more
Number of Targets: 1
T3D0672Adenosylcobalamin
13870-90-1
C72H100CoN18O17P
1579.582 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Cobalt Compound
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Organometallic
  • Pollutant
Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more
Number of Targets: 35
T3D1184Stryker's reagent
33636-93-0
C108H96Cu6P6
1961.036 g/mol
Thumb
  • Copper Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Synthetic Compound
Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more
Number of Targets: 6
T3D2487Apamin (Apis mellifera)
24345-16-2
Not Available
5223.305 g/mol
T3d2487
  • Amide
  • Amine
  • Animal Toxin
  • Insect Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Apamin binds to the SK channels (small conductance Ca2+-activated K+ channels) in the brain and spinal cord and inhibits them, likely by acting as a pore blocker. Inhi...more
Number of Targets: 3
Displaying toxin 3651 - 3675 of 3678 in total