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Displaying toxin 3426 - 3450 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D4738Encainide
66778-36-7
C22H28N2O2
352.470 g/mol
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  • Amide
  • Amine
  • Anti-Arrhythmia Agent
  • Drug
  • Ester
  • Ether
  • Organic Compound
  • Sodium Channel Blocker
  • Synthetic Compound
  • Voltage-Gated Sodium Channel Blocker
Encainide is a sodium channel blocker, binding to voltage gated sodium channels. It stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the in...more
Number of Targets: 1
T3D4739Imipenem
74431-23-5
C12H17N3O4S
299.346 g/mol
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  • Amide
  • Amine
  • Anti-Bacterial Agent
  • Drug
  • Ester
  • Ether
  • Organic Compound
  • Synthetic Compound
Imipenem acts as an antimicrobial through the inhibition of cell wall synthesis of various gram-positive and gram-negative bacteria. This inhibition of cell wall synth...more
Number of Targets: 0
T3D4740Hexestrol
84-16-2
C18H22O2
270.366 g/mol
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  • Drug
  • Organic Compound
  • Synthetic Compound
Not Available
Number of Targets: 16
T3D4741Aminopterin
54-62-6
C19H20N8O5
440.413 g/mol
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  • Amide
  • Amine
  • Drug
  • Ester
  • Folic Acid Antagonist
  • Food Toxin
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Aminopterin is an amino derivative of folic acid which binds competitively to the dihydrofolate reductase enzyme to block tetrahydrofolate synthesis. Tetrahydrofolate ...more
Number of Targets: 2
T3D4742Sodium Tetradecyl Sulfate
1191-50-0
C14H30O4S
294.451 g/mol
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  • Drug
  • Ester
  • Metabolite
  • Organic Compound
  • Sclerosing Solution
  • Surface-Active Agent
  • Synthetic Compound
Sodium tetradecyl sulfate is a potent toxin for endothelial cells in that brief exposure to even low concentrations are effective in stripping endothelium over a consi...more
Number of Targets: 18
T3D4743Ethinyl Estradiol
57-63-6
C20H24O2
296.403 g/mol
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  • Drug
  • Estrogen
  • Food Toxin
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Estrogens diffuse into their target cells and interact with a protein receptor. Target cells include the female reproductive tract, the mammary gland, the hypothalamus...more
Number of Targets: 17
T3D4744Diethylstilbestrol
56-53-1
C18H20O2
268.350 g/mol
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  • Carcinogen
  • Drug
  • Estrogen, Non-Steroidal
  • Food Toxin
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Estrogens diffuse into their target cells and interact with a protein receptor, the estrogen receptor. Target cells include the female reproductive tract, the mammary ...more
Number of Targets: 9
T3D4745Norethindrone
68-22-4
C20H26O2
298.419 g/mol
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  • Contraceptive, Oral, Synthetic
  • Drug
  • Ester
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Progestins diffuse freely into target cells and bind to the progesterone receptor. Target cells include the female reproductive tract, the mammary gland, the hypothala...more
Number of Targets: 6
T3D4746Estrone
53-16-7
C18H22O2
270.366 g/mol
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  • Animal Toxin
  • Anti-Menopausal Agent
  • Drug
  • Estrogen
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
Estrogens enter the cells of responsive tissues (e.g. female organs, breasts, hypothalamus, pituitary) where they interact with estrogen receptors. Hormone-bound estro...more
Number of Targets: 5
T3D4747Cyproterone acetate
427-51-0
C24H29ClO4
416.938 g/mol
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  • Drug
  • Ester
  • Ether
  • Organic Compound
  • Organochloride
  • Synthetic Compound
The direct antiandrogenic effect of cyproterone is blockage of the binding of dihydrotestosterone to the specific receptors in the prostatic carcinoma cell. In additio...more
Number of Targets: 4
T3D4748Methyltestosterone
58-18-4
C20H30O2
302.451 g/mol
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  • Anabolic Agent
  • Antineoplastic Agent, Hormonal
  • Drug
  • Ester
  • Hormone Replacement Agent
  • Metabolite
  • Organic Compound
  • Synthetic Compound
The effects of testosterone in humans and other vertebrates occur by way of two main mechanisms: by activation of the androgen receptor (directly or as DHT), and by co...more
Number of Targets: 4
T3D4749Levonorgestrel
797-63-7
C21H28O2
312.446 g/mol
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  • Contraceptive Agent
  • Contraceptive Agent, Female
  • Contraceptive, Oral, Synthetic
  • Drug
  • Ester
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Binds to the progesterone and estrogen receptors. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Once boun...more
Number of Targets: 7
T3D4750Busulfan
55-98-1
C6H14O6S2
246.302 g/mol
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  • Alkylating Agent
  • Antineoplastic Agent, Alkylating
  • Drug
  • Immunosuppressive Agent
  • Metabolite
  • Myeloablative Agonist
  • Organic Compound
  • Synthetic Compound
Busulfan is an alkylating agent that contains 2 labile methanesulfonate groups attached to opposite ends of a 4-carbon alkyl chain. Once busulfan is hydrolyzed, the me...more
Number of Targets: 2
T3D4751Dihydrotestosterone
521-18-6
C19H30O2
290.440 g/mol
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  • Androgen
  • Animal Toxin
  • Drug
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Steroid
Not Available
Number of Targets: 7
T3D4752Nitrofural
59-87-0
C6H6N4O4
198.136 g/mol
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  • Amine
  • Anti-Infective Agent
  • Drug
  • Household Toxin
  • Metabolite
  • Organic Compound
  • Synthetic Compound
The exact mechanism of action is unknown. Nitrofurazone inhibits several bacterial enzymes, especially those involved in the aerobic and anaerobic degradation of gluco...more
Number of Targets: 1
T3D4753Spironolactone
52-01-7
C24H32O4S
416.573 g/mol
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  • Diuretic
  • Drug
  • Ester
  • Ether
  • Metabolite
  • Mineralocorticoid Receptor Antagonist
  • Organic Compound
  • Synthetic Compound
Spironolactone is a specific pharmacologic antagonist of aldosterone, acting primarily through competitive binding of receptors at the aldosterone-dependent sodium-pot...more
Number of Targets: 15
T3D4754Testosterone Propionate
57-85-2
C22H32O3
344.488 g/mol
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  • Drug
  • Ester
  • Ether
  • Metabolite
  • Organic Compound
  • Synthetic Compound
The effects of testosterone in humans and other vertebrates occur by way of two main mechanisms: by activation of the androgen receptor (directly or as DHT), and by co...more
Number of Targets: 6
T3D4755Stearic acid
57-11-4
C18H36O2
284.477 g/mol
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  • Animal Toxin
  • Food Toxin
  • Household Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Pharmaceutic Aid
  • Plant Toxin
Not Available
Number of Targets: 7
T3D4756Triamcinolone
124-94-7
C21H27FO6
394.434 g/mol
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  • Anti-Inflammatory Agent
  • Drug
  • Ester
  • Glucocorticoid
  • Metabolite
  • Organic Compound
  • Organofluoride
  • Synthetic Compound
The antiinflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibition of arachidonic acid,...more
Number of Targets: 5
T3D4757Fulvestrant
129453-61-8
C32H47F5O3S
606.771 g/mol
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  • Antineoplastic Agent
  • Antineoplastic Agent, Hormonal
  • Drug
  • Estrogen Antagonist
  • Metabolite
  • Organic Compound
  • Organofluoride
  • Synthetic Compound
Fulvestrant competitively and reversibly binds to estrogen receptors present in cancer cells and achieves its anti-estrogen effects through two separate mechanisms. Fi...more
Number of Targets: 7
T3D4758Quercetin
117-39-5
C15H10O7
302.236 g/mol
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  • Antioxidant
  • Ester
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Quercetin is a specific quinone reductase 2 (QR2) inhibitor, an enzyme (along with the human QR1 homolog) which catalyzes metabolism of toxic quinolines. Inhibition of...more
Number of Targets: 12
T3D4759Liothyronine
6893-02-3
C15H12I3NO4
650.974 g/mol
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  • Amine
  • Animal Toxin
  • Drug
  • Ether
  • Food Toxin
  • Hormone Replacement Agent
  • Metabolite
  • Natural Compound
  • Organic Compound
The hormones, T4 and T3, are tyrosine-based hormones produced by the thyroid gland. Iodine is an important component in their synthesis. The major form of thyroid horm...more
Number of Targets: 10
T3D4760Alpha-Cyclodextrin (Cyclohexa-Amylose)
10016-20-3
C36H60O30
972.844 g/mol
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  • Food Toxin
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Not Available
Number of Targets: 2
T3D4761Butylbenzene
104-51-8
C10H14
134.218 g/mol
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  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Not Available
Number of Targets: 1
T3D47621,3-Butanediol
107-88-0
C4H10O2
90.121 g/mol
Thumb
  • Flavouring Agent
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
  • Solvent
Not Available
Number of Targets: 1
Displaying toxin 3426 - 3450 of 3678 in total