Browsing Toxins
Displaying toxin 3426 - 3450 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4738 | Encainide 66778-36-7 | C22H28N2O2 352.470 g/mol |  |
| Encainide is a sodium channel blocker, binding to voltage gated sodium channels. It stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the in...more Number of Targets: 1 |
| T3D4739 | Imipenem 74431-23-5 | C12H17N3O4S 299.346 g/mol |  |
| Imipenem acts as an antimicrobial through the inhibition of cell wall synthesis of various gram-positive and gram-negative bacteria. This inhibition of cell wall synth...more Number of Targets: 0 |
| T3D4740 | Hexestrol 84-16-2 | C18H22O2 270.366 g/mol |  |
| Not Available Number of Targets: 16 |
| T3D4741 | Aminopterin 54-62-6 | C19H20N8O5 440.413 g/mol |  |
| Aminopterin is an amino derivative of folic acid which binds competitively to the dihydrofolate reductase enzyme to block tetrahydrofolate synthesis. Tetrahydrofolate ...more Number of Targets: 2 |
| T3D4742 | Sodium Tetradecyl Sulfate 1191-50-0 | C14H30O4S 294.451 g/mol |  |
| Sodium tetradecyl sulfate is a potent toxin for endothelial cells in that brief exposure to even low concentrations are effective in stripping endothelium over a consi...more Number of Targets: 18 |
| T3D4743 | Ethinyl Estradiol 57-63-6 | C20H24O2 296.403 g/mol |  |
| Estrogens diffuse into their target cells and interact with a protein receptor. Target cells include the female reproductive tract, the mammary gland, the hypothalamus...more Number of Targets: 17 |
| T3D4744 | Diethylstilbestrol 56-53-1 | C18H20O2 268.350 g/mol |  |
| Estrogens diffuse into their target cells and interact with a protein receptor, the estrogen receptor. Target cells include the female reproductive tract, the mammary ...more Number of Targets: 9 |
| T3D4745 | Norethindrone 68-22-4 | C20H26O2 298.419 g/mol |  |
| Progestins diffuse freely into target cells and bind to the progesterone receptor. Target cells include the female reproductive tract, the mammary gland, the hypothala...more Number of Targets: 6 |
| T3D4746 | Estrone 53-16-7 | C18H22O2 270.366 g/mol |  |
| Estrogens enter the cells of responsive tissues (e.g. female organs, breasts, hypothalamus, pituitary) where they interact with estrogen receptors. Hormone-bound estro...more Number of Targets: 5 |
| T3D4747 | Cyproterone acetate 427-51-0 | C24H29ClO4 416.938 g/mol |  |
| The direct antiandrogenic effect of cyproterone is blockage of the binding of dihydrotestosterone to the specific receptors in the prostatic carcinoma cell. In additio...more Number of Targets: 4 |
| T3D4748 | Methyltestosterone 58-18-4 | C20H30O2 302.451 g/mol |  |
| The effects of testosterone in humans and other vertebrates occur by way of two main mechanisms: by activation of the androgen receptor (directly or as DHT), and by co...more Number of Targets: 4 |
| T3D4749 | Levonorgestrel 797-63-7 | C21H28O2 312.446 g/mol |  |
| Binds to the progesterone and estrogen receptors. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Once boun...more Number of Targets: 7 |
| T3D4750 | Busulfan 55-98-1 | C6H14O6S2 246.302 g/mol |  |
| Busulfan is an alkylating agent that contains 2 labile methanesulfonate groups attached to opposite ends of a 4-carbon alkyl chain. Once busulfan is hydrolyzed, the me...more Number of Targets: 2 |
| T3D4751 | Dihydrotestosterone 521-18-6 | C19H30O2 290.440 g/mol |  |
| Not Available Number of Targets: 7 |
| T3D4752 | Nitrofural 59-87-0 | C6H6N4O4 198.136 g/mol |  |
| The exact mechanism of action is unknown. Nitrofurazone inhibits several bacterial enzymes, especially those involved in the aerobic and anaerobic degradation of gluco...more Number of Targets: 1 |
| T3D4753 | Spironolactone 52-01-7 | C24H32O4S 416.573 g/mol |  |
| Spironolactone is a specific pharmacologic antagonist of aldosterone, acting primarily through competitive binding of receptors at the aldosterone-dependent sodium-pot...more Number of Targets: 15 |
| T3D4754 | Testosterone Propionate 57-85-2 | C22H32O3 344.488 g/mol |  |
| The effects of testosterone in humans and other vertebrates occur by way of two main mechanisms: by activation of the androgen receptor (directly or as DHT), and by co...more Number of Targets: 6 |
| T3D4755 | Stearic acid 57-11-4 | C18H36O2 284.477 g/mol |  |
| Not Available Number of Targets: 7 |
| T3D4756 | Triamcinolone 124-94-7 | C21H27FO6 394.434 g/mol |  |
| The antiinflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibition of arachidonic acid,...more Number of Targets: 5 |
| T3D4757 | Fulvestrant 129453-61-8 | C32H47F5O3S 606.771 g/mol |  |
| Fulvestrant competitively and reversibly binds to estrogen receptors present in cancer cells and achieves its anti-estrogen effects through two separate mechanisms. Fi...more Number of Targets: 7 |
| T3D4758 | Quercetin 117-39-5 | C15H10O7 302.236 g/mol |  |
| Quercetin is a specific quinone reductase 2 (QR2) inhibitor, an enzyme (along with the human QR1 homolog) which catalyzes metabolism of toxic quinolines. Inhibition of...more Number of Targets: 12 |
| T3D4759 | Liothyronine 6893-02-3 | C15H12I3NO4 650.974 g/mol |  |
| The hormones, T4 and T3, are tyrosine-based hormones produced by the thyroid gland. Iodine is an important component in their synthesis. The major form of thyroid horm...more Number of Targets: 10 |
| T3D4760 | Alpha-Cyclodextrin (Cyclohexa-Amylose) 10016-20-3 | C36H60O30 972.844 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D4761 | Butylbenzene 104-51-8 | C10H14 134.218 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4762 | 1,3-Butanediol 107-88-0 | C4H10O2 90.121 g/mol |  |
| Not Available Number of Targets: 1 |