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Displaying toxin 3651 - 3675 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D4977Edetic Acid
62-33-9
C10H16N2O8
292.243 g/mol
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  • Anticoagulant
  • Chelating Agent
  • Drug
  • Food Additive
  • Metabolite
  • Synthetic Compound
The pharmacologic effects of edetate calcium disodium are due to the formation of chelates with divalent and trivalent metals. A stable chelate will form with any meta...more
Number of Targets: 3
T3D4978Cytarabine
147-94-4
C9H13N3O5
243.217 g/mol
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  • Antimetabolite, Antineoplastic
  • Antiviral Agent
  • Drug
  • Immunosuppressive Agent
  • Metabolite
  • Synthetic Compound
Cytarabine acts through direct DNA damage and incorporation into DNA. Cytarabine is cytotoxic to a wide variety of proliferating mammalian cells in culture. It exhibit...more
Number of Targets: 3
T3D4979Isoprenaline
7683-59-2
C11H17NO3
211.258 g/mol
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  • Adrenergic beta-Agonist
  • Bronchodilator Agent
  • Cardiotonic Agent
  • Drug
  • Metabolite
  • Sympathomimetic
  • Synthetic Compound
The pharmacologic effects of isoproterenol are at least in part attributable to stimulation through beta-adrenergic receptors of intracellular adenyl cyclase, the enzy...more
Number of Targets: 7
T3D4980Atorvastatin
134523-00-5
C33H34FN2O5
557.632 g/mol
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  • Anticholesteremic Agent
  • Drug
  • Hydroxymethylglutaryl-CoA Reductase Inhibitor
  • Metabolite
  • Synthetic Compound
Atorvastatin selectively and competitively inhibits the hepatic enzyme HMG-CoA reductase. As HMG-CoA reductase is responsible for converting HMG-CoA to mevalonate in t...more
Number of Targets: 3
T3D4981Pioglitazone
111025-46-8
C19H20N2O3S
356.439 g/mol
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  • Drug
  • Hypoglycemic Agent
  • Metabolite
  • Synthetic Compound
Pioglitazone acts as an agonist at peroxisome proliferator activated receptors (PPAR) in target tissues for insulin action such as adipose tissue, skeletal muscle, and...more
Number of Targets: 3
T3D4982Dexamethasone
50-02-2
C22H29FO5
392.461 g/mol
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  • Anti-Inflammatory Agent
  • Antiemetic
  • Antineoplastic Agent, Hormonal
  • Drug
  • Glucocorticoid
  • Metabolite
  • Synthetic Compound
Dexamethasone is a glucocorticoid agonist. Unbound dexamethasone crosses cell membranes and binds with high affinity to specific cytoplasmic glucocorticoid receptors. ...more
Number of Targets: 7
T3D4983Tiratricol
51-24-1
C14H9I3O4
621.932 g/mol
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  • Industrial/Workplace Toxin
  • Synthetic Compound
Tiratricol is a naturally occurring metabolite of T4 (thyroxine) and a structural analog of T3 (triiodothyronine). Low concentrations of tiratricol are found in plasma...more
Number of Targets: 1
T3D4984Aniline
62-53-3
C6H7N
93.127 g/mol
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  • Carcinogen
  • Dye
  • Industrial/Workplace Toxin
  • Metabolite
  • Synthetic Compound
Aniline induces lipid peroxidation and protein oxidation in the spleen and that oxidative stress plays a role in the splenic toxicity of aniline. The hematopoietic sys...more
Number of Targets: 2
T3D4985Cinnamaldehyde
104-55-2
C9H8O
132.159 g/mol
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  • Food Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Pesticide
Cinnamaldehyde is an allergen. The physiologic effect of cinnamaldehyde is by means of increased histamine release and cell-mediated immunity.
Number of Targets: 2
T3D4986p-Anisidine
104-94-9
C7H9NO
123.153 g/mol
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  • Food Toxin
  • Metabolite
  • Natural Compound
  • Plant Toxin
p-Anisidine reacts with secondary oxidation products such as aldehydes and ketones in fats and oils. (Wikipedia)
Number of Targets: 0
T3D4987Dihydro-5-propyl-2(3H)-furanone
57129-71-2
C7H12O2
128.169 g/mol
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  • Food Toxin
  • Metabolite
  • Natural Compound
  • Plant Toxin
Not Available
Number of Targets: 0
T3D49889-(2-Carboxyphenyl)-3,6-bis(diethylamino)xanthylium(1+)
14899-08-2
C28H31N2O3
443.557 g/mol
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  • Dye
  • Food Additive
  • Food Toxin
  • Metabolite
  • Synthetic Compound
Not Available
Number of Targets: 0
T3D49893-Acetyl-4-hydroxy-6-methyl-2H-pyran-2-one
771-03-9
C8H8O4
168.147 g/mol
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  • Metabolite
  • Pesticide
  • Synthetic Compound
Not Available
Number of Targets: 0
T3D49902,2,4-Trimethyl-1,3-pentadienol diisobutyrate
6846-50-0
C16H30O4
286.407 g/mol
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  • Animal Toxin
  • Metabolite
  • Natural Compound
Not Available
Number of Targets: 0
T3D49919-Hydroxyphenanthrene
484-17-3
C14H10O
194.229 g/mol
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  • Animal Toxin
  • Metabolite
  • Natural Compound
9-phenanthrol is a recently identified inhibitor of the transient receptor potential melastatin (TRPM) 4 channel, a Ca(2+) -activated non-selective cation channel whos...more
Number of Targets: 0
T3D4992m-Dichlorobenzene
541-73-1
C6H4Cl2
147.002 g/mol
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  • Industrial/Workplace Toxin
  • Metabolite
  • Synthetic Compound
The liver damage caused in rats by 1,3-dichlorobenzene is accompanied by induction of xenobiotic metabolizing enzymes of the phenobarbital type. In rats, a disturbance...more
Number of Targets: 0
T3D49932-hydroxyflutamide
52806-53-8
C11H11F3N2O4
292.211 g/mol
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  • Animal Toxin
  • Metabolite
  • Natural Compound
Hydroxyflutamide is an antiandrogen. Antiandrogens alter the androgen pathway by blocking the appropriate receptors, competing for binding sites on the cell's surface,...more
Number of Targets: 0
T3D4994Dibenzylideneacetone
538-58-9
C17H14O
234.293 g/mol
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  • Cosmetic Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Synthetic Compound
Not Available
Number of Targets: 0
T3D499522,23-dihydroavermectin b1a
71827-03-7
C48H74O14
875.093 g/mol
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  • Antiparasitic Agent
  • Avermectin
  • Drug
  • Lachrymator
  • Metabolite
  • Synthetic Compound
Ivermectin binds selectively and with high affinity to glutamate-gated chloride ion channels in invertebrate muscle and nerve cells of the microfilaria. This binding c...more
Number of Targets: 14
T3D499622,23-dihydroavermectin b1b
70209-81-3
C47H72O14
861.066 g/mol
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  • Antiparasitic Agent
  • Avermectin
  • Drug
  • Lachrymator
  • Metabolite
  • Synthetic Compound
Ivermectin binds selectively and with high affinity to glutamate-gated chloride ion channels in invertebrate muscle and nerve cells of the microfilaria. This binding c...more
Number of Targets: 14
T3D4997Carbon-14
14762-75-5
CH4
18.035 g/mol
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  • Industrial/Workplace Toxin
  • Natural Compound
  • Organic Compound
  • Radioactive
Not Available
Number of Targets: 1
T3D4998Sulfur-35
15117-53-0
H2S
36.985 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Natural Compound
  • Non-Metal
  • Radioactive
Not Available
Number of Targets: 1
T3D4999Succinyl acetoacetate
65115-74-4
C8H10O6
202.161 g/mol
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  • Animal Toxin
  • Metabolite
  • Natural Compound
Not Available
Number of Targets: 0
T3D5000Sulfuric acid
7664-93-9
H2O4S
98.078 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Natural Compound
  • Non-Metal
Many strong acids cause tissue burns through the denaturation of proteins and partial hydrolysis of proteins. Most proteins denature at pH values of less than 3-4. T...more
Number of Targets: 0
T3D5001Succinic acid semialdehyde
692-29-5
C4H6O3
102.089 g/mol
ThumbNot AvailableNot Available
Number of Targets: 0
Displaying toxin 3651 - 3675 of 3678 in total